ModelCat AI, formerly the low-power chip pioneer Eta Compute, builds an agentic, hardware-aware platform that automatically designs, trains, optimizes and validates machine-learning models for embedded, edge and IoT devices. Its patented AI-in-the-Loop workflow, backed by a physical hardware farm that calibrates results against real silicon, compresses a model-development cycle that once took 12 to 24 months down to a matter of days. The Sunnyvale company works with chipmakers including NXP and Alif Semiconductor to hand developers ready-to-run models tuned to the exact constraints of the hardware they will run on.
Ability Biotherapeutics (also known as Ability Biologics) is a Montreal-based biotech founded in 2023 that engineers highly selective, immune-cell-modulating antibody therapeutics for cancer and autoimmune disease. Its AbiLeap discovery engine pairs continuously learning AI with one of the largest antibody-antigen interaction databases ever assembled to generate fully human, IgG-based multispecific antibodies that sense their environment and act only where intended - so-called logic-gated therapeutics. Backed by US$18M in seed capital led by Amplitude Ventures, the company is advancing a pipeline of immuno-oncology and autoimmune candidates toward preclinical readiness.
Consilient is a New York- and Washington, D.C.-based financial technology company that applies federated machine learning to anti-money laundering and financial crime detection. Its models learn from behavioral patterns across multiple banks and share the algorithms - not the underlying customer data - so institutions can collaborate on catching illicit activity while preserving privacy. Founded in 2020 as a joint venture between K2 Integrity and Giant Oak, the company's Dozer platform has demonstrated in bank trials that it can sharply cut false positives while improving true-positive detection.
HarvestAi is a Potsdam-based agritech company that builds AI software for high-tech greenhouses. Its web platform combines computer vision, machine learning and plant-physiology modeling to predict crop growth, harvest dates and yields, giving greenhouse operators forecasts that its team says exceed 90% accuracy. Growers use it to negotiate sales earlier, plan labor and logistics, and cut waste and energy costs. Founded in 2020 and led by CEO Dr. Georg Caspary, the company has raised roughly EUR 2.97M in seed funding and won first prize in Food/Agritech at Slush.
Integrated Projects is a New York-based building-intelligence company that turns any physical building into accurate as-built digital plans. Through its IPX platform, it pairs LiDAR reality-capture (SCANIT) with machine-learning-driven point-cloud-to-BIM conversion (BIMIT) to produce standardized LOD200-LOD300 BIM and CAD files that owners, architects, engineers and contractors can view, query, measure and share in a browser. The company's pitch is simple: before you can renovate what a building should be, you have to accurately document what it is.
Latent Knowledge is a New York-based AI company building LitView, a semantic search and literature-visualization tool that helps R&D teams and academic researchers discover, cluster, and map scientific literature beyond simple keyword matching. Founded in 2019 by James Reilly, the company uses applied natural language processing to surface hidden links between technical articles and speed up the research process across public and private data sources.
Nervio is an Israeli-American digital health company building AIM, an AI-powered intraoperative neuromonitoring (IONM) system that turns raw surgical signal data into real-time alerts and recommendations. Founded in 2020 by brothers Dr. Omer Zarchi and Nir Zarchi, the company aims to prevent avoidable paralysis and nerve injury during spine and neurosurgery at a time when the number of surgeries is climbing and the pool of expert neurophysiologists is shrinking. Nervio operates from Nashville, Tennessee with an R&D center in Israel, and its technology has been developed with input from dozens of neurophysiologists across more than 1,000 surgical cases.
Rentana is an AI-powered revenue intelligence platform for multifamily real estate owners and operators. It replaces spreadsheet-driven pricing with real-time, unit-level recommendations - optimizing rents, amenity values, marketing specials, and lease renewals in one platform. Founded in 2023 by a team out of Stripe, Airtable, Airbnb, and AppFolio and led by ex-Two Sigma investor Julie Blanc, Rentana raised a $5M seed round in 2025 and reports outcomes like millions in added property value and roughly 10 hours saved per property each week.
Talus Bio is a Seattle drug-discovery company going after transcription factors and other regulatory proteins long written off as 'undruggable.' Its MARMOT platform measures the human regulome directly in living cells using functional proteomics and high-throughput mass spectrometry, then feeds tens of millions of compound-target interactions into a lab-in-the-loop AI system to design small molecules that switch disease-driving genes on or off. Founded in 2020 by Alex Federation and Lindsay Pino, the company runs preclinical programs in chordoma, non-small cell lung cancer, and prostate cancer.

Jon Carr-Harris is the Founder & CEO of CRED, a San Francisco-based AI-powered predictive intelligence platform that raised $15M in seed funding in June 2025. CRED unifies data from 200+ integrations and 10,000+ external sources to deliver business predictions 60-90 days in advance with 92% claimed accuracy - giving enterprises the kind of forward-looking intelligence once reserved for hedge funds. A serial entrepreneur who advised Airbnb, Kik, and Khan Academy early in their growth, Carr-Harris built and exited Swish Labs (a global tech consulting ecosystem spanning 30+ countries) before founding CRED in 2023, which emerged from stealth with 25 enterprise clients and $100M+ in documented customer revenue impact.
Joe Chin is the Co-Founder and CEO of Sparrow, a New York-based sports AI startup using edge AI and computer vision to analyze athletic motion in real time. A 4x serial entrepreneur with 22+ years of leadership experience and three prior exits, Joe built Sparrow around a simple observation: golfers forget lessons the moment they leave the range. Sparrow's flagship golf app has helped 250,000+ golfers analyze their swing against a dataset of 1 million pro golf data points, delivering instant, personalized feedback via smartphone. The company has raised $8.27M in total funding and is expanding into soccer, basketball, and other major sports.
Jorge Heraud is a Peruvian-born engineer and serial agtech founder who co-founded Blue River Technology — sold to John Deere for $305 million in 2017 — and is now CEO of TerraBlaster, a Redwood City startup using NASA-pioneered laser spectroscopy to give farmers real-time soil nutrient data, aiming to cut fertilizer waste and transform how agriculture feeds the world.

Swyx (Shawn Wang) and Alessio Fanelli are the co-hosts of Latent Space, the #1 AI Engineering podcast and newsletter with 200,000+ subscribers and 10M+ total readers. Swyx — a former Singapore hedge fund trader turned developer advocate who coined the term 'AI Engineer' — and Alessio — a Forbes 30 Under 30 VC partner and Rome-born dropout-turned-engineer — together define the curriculum and culture of a generation of engineers building with AI.
Abalone Bio is an Emeryville-based preclinical biotech building target-activating antibodies for diseases other drugs can't reach. Its FAST platform pairs engineered yeast cells with AI/ML to screen ~100 million antibodies per experiment for functional activity, not just binding, with an initial focus on G-protein coupled receptors (GPCRs) and metabolic disease.
Atlas AI is a Palo Alto-based Public Benefit Corporation building GeoAI software that turns planetary-scale satellite imagery, ground-truth surveys, and predictive models into decision-support tools for enterprises, governments, and development institutions investing in emerging markets.
Avenue Biosciences is a transatlantic biotech building the first platform to measure and modulate the cellular secretory pathway at scale. Spun out of the University of Helsinki and headquartered between Helsinki and Palo Alto, the company pairs high-throughput chemistry with machine learning to design signal peptides and boost yields of therapeutic proteins - biologics, biosimilars, and mRNA-encoded medicines - so that production bottlenecks stop limiting which therapies reach patients.
Bifrost AI builds simulation and evaluation infrastructure for physical AI. Its platform generates photorealistic 3D synthetic data and stress-tests robotics and computer-vision systems across thousands of simulated scenarios - weather, sensor noise, rare edge cases - so teams can train and validate models in minutes instead of months. Used across maritime, geospatial, aerial, off-road, industrial, and off-world domains, with collaborators including NASA JPL and the U.S. Air Force. Founded in 2020 and backed by an $8M Series A led by Carbide Ventures with participation from Airbus Ventures and Peak XV's Surge.
Gordian Biotechnology is a South San Francisco in vivo drug discovery company building a high-throughput screening platform that tests hundreds of gene therapies simultaneously inside animals that naturally develop age-related diseases. By pairing 'patient avatar' models with single-cell transcriptomics and machine learning (a stack the company calls Mosaic Screening + Pythia), Gordian aims to predict human clinical outcomes earlier and cure complex diseases of aging.
identifeye HEALTH (formerly Tesseract Health) builds an AI-powered retinal imaging platform that turns a quick eye scan in a primary-care clinic into a window onto whole-body health, helping clinicians screen for diabetic retinopathy, glaucoma and macular degeneration without dilation or specialty equipment.
Inception builds diffusion-based large language models (dLLMs) that generate text in parallel instead of one token at a time. Its flagship Mercury family is positioned as the first commercial-scale diffusion LLM, reporting 5–10x faster throughput than traditional autoregressive models at competitive quality, with Mercury Coder targeting code generation and Mercury 2 reasoning workloads.
Kimia Therapeutics is a Berkeley-based biotech building ATLAS, a drug-discovery platform that pairs nanoliter-scale high-throughput precision chemistry with machine learning and genome editing to map the druggable space at single-atom resolution. Spun out of Carmot Therapeutics in 2023 and backed by $55M in Series A funding, Kimia is using its chemical atlas to advance therapeutic programs in cancer and immunology.
Mindee is a Paris- and San Francisco-based AI company building an API-first platform that turns any document - invoices, receipts, passports, bank statements - into clean structured JSON. Founded in 2018 and backed by GGV Capital, Alven and Y Combinator, it gives developers pre-trained OCR endpoints plus a no-training-required custom builder called docTI.
MindsDB is an open-source AI data platform that lets developers connect, unify, and query structured and unstructured data across 200+ sources using SQL and natural language - turning any database into an AI-ready system without moving data.
Prophia is a San Francisco-based AI platform that turns the messy stack of commercial real estate lease documents into structured, searchable, decision-ready data. Founded in 2018 by Cameron Steele and Chris Hsu, the company combines machine learning with human quality control to deliver lease abstracts, rent rolls, and portfolio insights for CRE owners and asset managers.
Qnovo is a Milpitas, California software company that makes lithium-ion batteries smarter. Its intelligent battery management platform - powering SpectralX adaptive fast charging and SentinelX safety diagnostics - is embedded in more than 150 million smartphones and increasingly in EVs from the world's top automakers, helping prevent fires, extend range, and stretch battery life.
RIOS Intelligent Machines was a Menlo Park robotics company building AI-powered dexterous robots for factories, warehouses, and supply chains. Founded in 2018 by former Xerox PARC engineers, RIOS pioneered haptic intelligence and tactile sensing for industrial robots, deploying systems across e-commerce, manufacturing, food processing, and wood products before archiving the company in 2026.
PDF Solutions is a Santa Clara semiconductor analytics company that turns the firehose of chip-manufacturing and test data into decisions. Its Exensio platform connects fabs, foundries, OSATs and fabless designers, normalizing data across silos so customers can ramp yield faster, catch defects earlier and run AI/ML models on the factory floor. Founded in 1991 and public since 2001 (Nasdaq: PDFS), it serves 130+ semiconductor companies including TSMC, Intel, Qualcomm, Analog Devices and DENSO.
Prodigal is a Mountain View-based AI company building the only intelligence platform purpose-built for consumer finance. Trained on more than a billion real U.S. lending and collections interactions, its AI agents and applications - proAgent, proCollect, proPay, proScore, proNotes, proAssist and the PIE intelligence engine - help banks, lenders, auto-finance firms, collections agencies and healthcare revenue teams collect more payments, cut costs and stay compliant. More than 100 companies run on Prodigal, which has processed over a billion consumer interactions to date.
Atomic AI is a South San Francisco biotechnology company fusing machine learning with structural biology to unlock RNA drug discovery. Its platform pairs in-house wet-lab chemical-mapping data with deep learning models - including ATOM-1, a foundation model for RNA structure, and PARSE, its RNA structure exploration platform - to find structured, ligandable RNA motifs and design selective small molecules and RNA-based medicines for targets long considered undruggable.
Biorce is a Barcelona-based healthtech company building AI-native infrastructure for clinical trials. Its core product, Aika, helps pharmaceutical companies, biotechs and CROs design regulator-ready trial protocols in roughly 90 seconds, drawing on a corpus of more than one million clinical studies and 260,000+ protocols. By cutting protocol design time by at least 50% and flagging regulatory and feasibility risks early, Biorce aims to compress the years and billions of dollars it takes to bring a drug to market - so treatments reach patients sooner. In February 2026 it closed a USD $52.5M Series A led by DST Global, the largest Series A to date in the Iberian healthtech and AI ecosystem.