ammune.ai (formerly L7 Defense) is a cybersecurity company that builds ammune™, a fully autonomous, AI-based platform for protecting APIs - and, increasingly, AI systems and data centers - from cyberattacks. Using unsupervised machine learning, ammune auto-discovers APIs and builds a tailored protection layer for each one inline from the first request, blocking dozens of attack types (bots, DDoS, business-logic abuse, injection) in real time without pre-training or rule-writing. The platform is platform-agnostic, running on-premises, in the cloud, in Kubernetes clusters, and offloaded onto DPUs such as NVIDIA BlueField-2, and it recently expanded toward offline, air-gapped protection for AI workloads.
First Access is a New York-based fintech company that gives lenders in emerging markets a configurable software platform to originate loans and make credit decisions. Founded in 2011, it began by scoring the creditworthiness of people outside the formal financial system using mobile phone and alternative data, then grew into a full loan-origination and decision-engine platform that lets microfinance institutions and small-business lenders digitize operations, launch custom credit applications in roughly two weeks, and automate underwriting while keeping room for human judgment.
RapidCanvas is an Austin-based enterprise AI company that helps businesses move from concept to production-ready AI solutions in weeks rather than months. Founded in 2021 by veterans of Simility (acquired by PayPal), it pairs a proprietary agentic AI platform with human experts through what it calls the Hybrid Approach - AI agents automate data preparation, modeling and workflow execution while human specialists handle strategy and governance. The company targets non-technical business users across manufacturing, financial services, retail, energy and logistics, and has raised over $23.5M including a $16M Series A led by Peak XV Partners.
Univfy is a California-based health-AI company that uses machine learning to give IVF patients personalized, center-specific predictions of their probability of a live birth. Founded by Stanford researchers Dr. Mylene Yao and Prof. Wing H. Wong, its platform analyzes thousands of real IVF cycles to move beyond age-only estimates, powering patient counseling, fertility benefits for employers and health plans, and IVF refund/warranty programs that make treatment more affordable and predictable.
Databricks is a San Francisco-based data and AI company founded in 2013 by the original creators of Apache Spark. It builds the Data Intelligence Platform - a lakehouse architecture that unifies data engineering, analytics, and machine learning on open formats. Used by more than 10,000 organizations worldwide, Databricks helps enterprises store, govern, and analyze data and build AI applications on top of it, all under a single governance model.
AppLovin is a Palo Alto-based advertising technology company that runs an AI-driven marketplace connecting app advertisers with the users most likely to engage with them. Founded in 2011, it grew from a mobile-gaming ad network into an S&P 500 company by building AXON, a machine-learning engine that matches advertiser demand to publisher supply in real time. After selling its own games portfolio in 2025, AppLovin now focuses almost entirely on high-margin advertising software, expanding beyond gaming into e-commerce and connected TV.
NVIDIA is an American technology company that designs graphics processing units (GPUs) and the accelerated-computing platforms built around them. Founded in 1993 to chase realistic 3D graphics for video games, it turned its parallel-processing chips and the CUDA software layer into the dominant engine of the modern AI boom. Today its data-center systems train and run most of the world's large AI models, and the company sits at the center of the semiconductor industry with a market value above $5 trillion.
Dataro is a predictive AI platform that helps nonprofit fundraising teams turn their existing donor data into ranked, day-to-day actions. It analyzes data inside a charity's CRM to score every donor, flag who is at risk of lapsing or ready to give, and recommend the next best step - so teams can prioritize the right supporters without increasing outreach. Used by more than 300 organizations across 20+ countries, including World Central Kitchen, Amnesty International, Save the Children and Greenpeace, Dataro raised a $14.28M Series A in February 2026 led by Blueprint Equity.
Karius is a Redwood City, California life-sciences company that turns a single blood draw into a broad infectious-disease diagnosis. Its flagship Karius Test uses microbial cell-free DNA (mcfDNA) sequencing, metagenomics and AI to detect more than 1,000 pathogens - bacteria, DNA viruses, fungi and parasites - often within a day of receiving a sample. Founded in 2014 out of Stephen Quake's lab at Stanford, the company aims to give clinicians a fast, non-invasive alternative to invasive biopsies and slow cultures, with a focus on the immunocompromised patients who need answers most urgently.
ModelCat AI, formerly the low-power chip pioneer Eta Compute, builds an agentic, hardware-aware platform that automatically designs, trains, optimizes and validates machine-learning models for embedded, edge and IoT devices. Its patented AI-in-the-Loop workflow, backed by a physical hardware farm that calibrates results against real silicon, compresses a model-development cycle that once took 12 to 24 months down to a matter of days. The Sunnyvale company works with chipmakers including NXP and Alif Semiconductor to hand developers ready-to-run models tuned to the exact constraints of the hardware they will run on.
Ability Biotherapeutics (also known as Ability Biologics) is a Montreal-based biotech founded in 2023 that engineers highly selective, immune-cell-modulating antibody therapeutics for cancer and autoimmune disease. Its AbiLeap discovery engine pairs continuously learning AI with one of the largest antibody-antigen interaction databases ever assembled to generate fully human, IgG-based multispecific antibodies that sense their environment and act only where intended - so-called logic-gated therapeutics. Backed by US$18M in seed capital led by Amplitude Ventures, the company is advancing a pipeline of immuno-oncology and autoimmune candidates toward preclinical readiness.
Consilient is a New York- and Washington, D.C.-based financial technology company that applies federated machine learning to anti-money laundering and financial crime detection. Its models learn from behavioral patterns across multiple banks and share the algorithms - not the underlying customer data - so institutions can collaborate on catching illicit activity while preserving privacy. Founded in 2020 as a joint venture between K2 Integrity and Giant Oak, the company's Dozer platform has demonstrated in bank trials that it can sharply cut false positives while improving true-positive detection.
HarvestAi is a Potsdam-based agritech company that builds AI software for high-tech greenhouses. Its web platform combines computer vision, machine learning and plant-physiology modeling to predict crop growth, harvest dates and yields, giving greenhouse operators forecasts that its team says exceed 90% accuracy. Growers use it to negotiate sales earlier, plan labor and logistics, and cut waste and energy costs. Founded in 2020 and led by CEO Dr. Georg Caspary, the company has raised roughly EUR 2.97M in seed funding and won first prize in Food/Agritech at Slush.
Integrated Projects is a New York-based building-intelligence company that turns any physical building into accurate as-built digital plans. Through its IPX platform, it pairs LiDAR reality-capture (SCANIT) with machine-learning-driven point-cloud-to-BIM conversion (BIMIT) to produce standardized LOD200-LOD300 BIM and CAD files that owners, architects, engineers and contractors can view, query, measure and share in a browser. The company's pitch is simple: before you can renovate what a building should be, you have to accurately document what it is.
Latent Knowledge is a New York-based AI company building LitView, a semantic search and literature-visualization tool that helps R&D teams and academic researchers discover, cluster, and map scientific literature beyond simple keyword matching. Founded in 2019 by James Reilly, the company uses applied natural language processing to surface hidden links between technical articles and speed up the research process across public and private data sources.
Nervio is an Israeli-American digital health company building AIM, an AI-powered intraoperative neuromonitoring (IONM) system that turns raw surgical signal data into real-time alerts and recommendations. Founded in 2020 by brothers Dr. Omer Zarchi and Nir Zarchi, the company aims to prevent avoidable paralysis and nerve injury during spine and neurosurgery at a time when the number of surgeries is climbing and the pool of expert neurophysiologists is shrinking. Nervio operates from Nashville, Tennessee with an R&D center in Israel, and its technology has been developed with input from dozens of neurophysiologists across more than 1,000 surgical cases.
Rentana is an AI-powered revenue intelligence platform for multifamily real estate owners and operators. It replaces spreadsheet-driven pricing with real-time, unit-level recommendations - optimizing rents, amenity values, marketing specials, and lease renewals in one platform. Founded in 2023 by a team out of Stripe, Airtable, Airbnb, and AppFolio and led by ex-Two Sigma investor Julie Blanc, Rentana raised a $5M seed round in 2025 and reports outcomes like millions in added property value and roughly 10 hours saved per property each week.
Talus Bio is a Seattle drug-discovery company going after transcription factors and other regulatory proteins long written off as 'undruggable.' Its MARMOT platform measures the human regulome directly in living cells using functional proteomics and high-throughput mass spectrometry, then feeds tens of millions of compound-target interactions into a lab-in-the-loop AI system to design small molecules that switch disease-driving genes on or off. Founded in 2020 by Alex Federation and Lindsay Pino, the company runs preclinical programs in chordoma, non-small cell lung cancer, and prostate cancer.

Jon Carr-Harris is the Founder & CEO of CRED, a San Francisco-based AI-powered predictive intelligence platform that raised $15M in seed funding in June 2025. CRED unifies data from 200+ integrations and 10,000+ external sources to deliver business predictions 60-90 days in advance with 92% claimed accuracy - giving enterprises the kind of forward-looking intelligence once reserved for hedge funds. A serial entrepreneur who advised Airbnb, Kik, and Khan Academy early in their growth, Carr-Harris built and exited Swish Labs (a global tech consulting ecosystem spanning 30+ countries) before founding CRED in 2023, which emerged from stealth with 25 enterprise clients and $100M+ in documented customer revenue impact.
Joe Chin is the Co-Founder and CEO of Sparrow, a New York-based sports AI startup using edge AI and computer vision to analyze athletic motion in real time. A 4x serial entrepreneur with 22+ years of leadership experience and three prior exits, Joe built Sparrow around a simple observation: golfers forget lessons the moment they leave the range. Sparrow's flagship golf app has helped 250,000+ golfers analyze their swing against a dataset of 1 million pro golf data points, delivering instant, personalized feedback via smartphone. The company has raised $8.27M in total funding and is expanding into soccer, basketball, and other major sports.
Jorge Heraud is a Peruvian-born engineer and serial agtech founder who co-founded Blue River Technology — sold to John Deere for $305 million in 2017 — and is now CEO of TerraBlaster, a Redwood City startup using NASA-pioneered laser spectroscopy to give farmers real-time soil nutrient data, aiming to cut fertilizer waste and transform how agriculture feeds the world.

Swyx (Shawn Wang) and Alessio Fanelli are the co-hosts of Latent Space, the #1 AI Engineering podcast and newsletter with 200,000+ subscribers and 10M+ total readers. Swyx — a former Singapore hedge fund trader turned developer advocate who coined the term 'AI Engineer' — and Alessio — a Forbes 30 Under 30 VC partner and Rome-born dropout-turned-engineer — together define the curriculum and culture of a generation of engineers building with AI.
Abalone Bio is an Emeryville-based preclinical biotech building target-activating antibodies for diseases other drugs can't reach. Its FAST platform pairs engineered yeast cells with AI/ML to screen ~100 million antibodies per experiment for functional activity, not just binding, with an initial focus on G-protein coupled receptors (GPCRs) and metabolic disease.
Atlas AI is a Palo Alto-based Public Benefit Corporation building GeoAI software that turns planetary-scale satellite imagery, ground-truth surveys, and predictive models into decision-support tools for enterprises, governments, and development institutions investing in emerging markets.
Avenue Biosciences is a transatlantic biotech building the first platform to measure and modulate the cellular secretory pathway at scale. Spun out of the University of Helsinki and headquartered between Helsinki and Palo Alto, the company pairs high-throughput chemistry with machine learning to design signal peptides and boost yields of therapeutic proteins - biologics, biosimilars, and mRNA-encoded medicines - so that production bottlenecks stop limiting which therapies reach patients.
Bifrost AI builds simulation and evaluation infrastructure for physical AI. Its platform generates photorealistic 3D synthetic data and stress-tests robotics and computer-vision systems across thousands of simulated scenarios - weather, sensor noise, rare edge cases - so teams can train and validate models in minutes instead of months. Used across maritime, geospatial, aerial, off-road, industrial, and off-world domains, with collaborators including NASA JPL and the U.S. Air Force. Founded in 2020 and backed by an $8M Series A led by Carbide Ventures with participation from Airbus Ventures and Peak XV's Surge.
Gordian Biotechnology is a South San Francisco in vivo drug discovery company building a high-throughput screening platform that tests hundreds of gene therapies simultaneously inside animals that naturally develop age-related diseases. By pairing 'patient avatar' models with single-cell transcriptomics and machine learning (a stack the company calls Mosaic Screening + Pythia), Gordian aims to predict human clinical outcomes earlier and cure complex diseases of aging.
identifeye HEALTH (formerly Tesseract Health) builds an AI-powered retinal imaging platform that turns a quick eye scan in a primary-care clinic into a window onto whole-body health, helping clinicians screen for diabetic retinopathy, glaucoma and macular degeneration without dilation or specialty equipment.
Inception builds diffusion-based large language models (dLLMs) that generate text in parallel instead of one token at a time. Its flagship Mercury family is positioned as the first commercial-scale diffusion LLM, reporting 5–10x faster throughput than traditional autoregressive models at competitive quality, with Mercury Coder targeting code generation and Mercury 2 reasoning workloads.
Kimia Therapeutics is a Berkeley-based biotech building ATLAS, a drug-discovery platform that pairs nanoliter-scale high-throughput precision chemistry with machine learning and genome editing to map the druggable space at single-atom resolution. Spun out of Carmot Therapeutics in 2023 and backed by $55M in Series A funding, Kimia is using its chemical atlas to advance therapeutic programs in cancer and immunology.