Amperos Health is a New York-based healthcare technology company building agentic AI that automates insurance denial management and revenue recovery for medical providers. Its AI biller, Amanda, works inside providers' existing billing systems to follow up on claims, place calls to payors, file appeals, and collect on denied and outstanding claims. Amperos serves more than 3,000 clinical locations across all 50 states and supports roughly $700 million in annual recovered revenue across 500,000+ claims. The company raised a $16M Series A led by Bessemer Venture Partners in April 2026, bringing total funding to about $20.2M.
Arya Health is a New York-based healthcare technology company building AI-powered digital agents that automate the non-clinical administrative work of distributed care - onboarding, scheduling, compliance, payroll, and hiring. Its agents plug into existing electronic medical records so home health and post-acute providers can spend more of every dollar on patients and caregivers instead of paperwork. Founded in 2022 by Kunal Sarda and Arunram Kalaiselvan, the company raised an $18.2M Series A in 2025 led by ACME Capital, bringing total funding to roughly $25M.
Briya is a healthcare data company that connects hospitals, health systems, and researchers to life sciences organizations through a secure, privacy-preserving data exchange network. Its blockchain-secured infrastructure standardizes electronic health records and keeps data at its source, while its flagship product, Briya AIRE, is a clinical-grade conversational AI research platform that lets scientists query and analyze real-world medical data in plain language. Founded in 2020 by David Lazerson and Guy Tish, Briya spans a global network of more than 120 million patient records and aims to accelerate medical and epidemiological research without the friction of traditional data integration.
Cassidy is a New York-based enterprise AI platform that lets non-technical teams build AI agents and multi-step automations powered by their own internal company data. By connecting large language models to a business's knowledge base, tools, and real-time data, Cassidy automates complex, context-heavy workflows - customer support triage, RFP responses, CRM updates from sales calls, lead qualification and internal knowledge sharing - without writing code. Founded in 2023 by Justin Fineberg and Ian Woodfill, the company raised a $10M Series A in 2025 and is used by more than 20,000 teams.
Castor is a health-technology company that builds a cloud-based eClinical platform for running clinical trials - from electronic data capture (EDC) and eConsent to eCOA/ePRO and real-world evidence. Founded in 2012 in Amsterdam by physician-researcher Dr. Derk Arts, Castor set out to replace clunky, expensive trial software with a self-service, researcher-friendly system. Today it supports more than 15,000 studies across 90+ countries and is used by leading CROs and biopharma companies, while pushing decentralized trials and practical AI (Castor Catalyst, built with Google Cloud) into mainstream research.
This Microsoft customer story details how healthcare technology startup Subsalt built a HIPAA-compliant synthetic data sandbox on Microsoft Azure and Microsoft Fabric to help medical researchers and students at UT Southwestern Medical Center access real-quality clinical data in days instead of months, accelerating research outcomes while safeguarding patient privacy.
Compyl is a New York-based SaaS company that unifies governance, risk, and compliance (GRC) on a single platform. Founded in 2020 by former CISOs, it pulls evidence directly from more than 125 integrated systems, maps controls across 70+ frameworks like SOC 2, ISO 27001 and HIPAA, and uses agentic AI to draft evidence, score vendors and answer security questionnaires while keeping humans in control of decisions. Compyl raised a $12M Series A in June 2025 to scale its AI-led platform for mid-market and enterprise security teams.
Ethermed is a Philadelphia-based health technology company that uses large language models and clinical reasoning to automate prior authorization - the paperwork-heavy approval process between healthcare providers and insurers. Its platform intercepts physician orders, gathers documentation, compares payer guidelines, fills forms and submits requests with an audit trail, cutting approval times from days to minutes. Founded in 2021 by Dan Friedman and Michal Such, the company raised an $8.5M Series A in April 2026, bringing total funding above $15M.
Predoc is a New York-based, clinician-founded startup building an AI-native platform for health information management. It automates the retrieval, cleaning, and structuring of patient medical records - pulling data from digital sources, faxes, and direct provider requests - and turns fragmented, unstructured documents into normalized, actionable data that plugs into existing clinical and research systems. Founded in 2022, the company raised $30M (Series A led by Base10 Partners) and serves oncology groups, research networks, and virtual care providers.
Thoropass is a New York-based compliance and audit company that pairs compliance-automation software with an in-house, tech-enabled CPA and security audit firm. Founded in 2019 as Laika and rebranded in 2023, it lets companies get and stay certified across 30+ frameworks - SOC 2, ISO 27001, HIPAA, PCI DSS, HITRUST, GDPR, and ISO 42001 for AI - through a single platform where the auditor is assigned on day one. By reusing evidence across frameworks and layering AI features like First Pass AI and Smart Sort AI on top of continuous control monitoring, Thoropass helps growing businesses complete audits meaningfully faster than the traditional consultant-plus-auditor route.
Chorology, Inc. is a San Jose-based data security and compliance startup that uses a Deep-AI 'knowledge encoding' engine - rather than conventional machine learning - to automatically discover, classify, and map an enterprise's sensitive data across structured and unstructured repositories. Its flagship platform, CAPE (Compliance and Posture Enforcer), aims to give organizations a continuous, mandate-agnostic view of where regulated data lives so they can enforce data security posture and meet frameworks like GDPR, CCPA, and HIPAA. Founded by serial cybersecurity entrepreneur Tarique Mustafa, the company emerged from stealth in July 2024 with $9M in funding and a roster of early Fortune 500 users.
Collectly is a San Francisco-based healthcare fintech that automates the patient side of revenue cycle management. Its AI platform plugs into more than 20 EHR and practice-management systems to run digital billing, eligibility checks, cost estimates, payments and follow-up, so medical groups collect more, faster, with fewer staff hours. Founded in 2017 and a Y Combinator graduate, Collectly says it serves 3,000+ healthcare facilities and has processed over $1 billion in patient payments. In 2025 it launched Billie, a 24/7 AI agent that answers patient billing questions and takes action across voice, chat, text and email.
Lightbeam is a San Jose-based data security and privacy company that converges DSPM, privacy operations, and AI governance into one identity-centric platform. Founded in 2020 by ex-Nutanix engineers, it uses AI to discover, classify, and map sensitive data across cloud, SaaS, and on-prem environments, tying each data fragment back to the human it belongs to. Customers in banking, healthcare, insurance, and tech use Lightbeam to automate compliance with GDPR, CCPA, HIPAA, and PCI while cutting data risk and controlling AI exposure through tools like Microsoft Copilot, ChatGPT Enterprise, and Google Gemini.
Vectara is a Palo Alto-based enterprise AI company building a trusted, end-to-end platform for retrieval-augmented generation (RAG) and AI agents. Founded in 2022 by former Google AI researchers, it lets companies embed grounded, citation-backed GenAI - conversational assistants, semantic search, and agents - into their products while actively detecting and correcting hallucinations at runtime. Its stack includes the Boomerang embedding model, the RAG-tuned Mockingbird LLM, the open-source Hughes Hallucination Evaluation Model (HHEM), and a Guardian Agent layer, positioning Vectara as a leader in factual, secure, compliance-ready enterprise AI.
Zania builds autonomous AI agents for governance, risk, and compliance (GRC). Founded in 2023 by former CISO Shruti Gupta, the Palo Alto company deploys domain-specific 'AI teammates' that run third-party risk reviews, controls testing, evidence collection, security questionnaires, and continuous compliance across frameworks like SOC 2, ISO 27001, and HIPAA - work it claims runs up to 30x faster at 90% lower cost with 94%+ accuracy. It raised an $18M Series A led by NEA in 2025.
Shubh Sinha is the co-founder and CEO of Integral Privacy Technologies, a San Francisco company that certifies, transforms, and activates privacy-regulated data (HIPAA, GDPR, CCPA) for healthcare and other regulated industries. Integral compresses compliance workflows that once took months into hours. Before Integral, Sinha led regulated-data product work at LiveRamp. He is a Purdue-trained computer engineer, an angel investor, and a Forbes Technology Council member. In July 2026 the company raised its Series A, bringing total funding to about $25M.
Zain Qayyum is the co-founder and co-CEO of Medsender, a New York based healthcare automation company that uses AI to turn faxes, emails and phone calls into structured data that flows straight into patient records. A pre-med student who walked away from medicine after watching hospitals shuttle paper and CDs between systems, he built a platform now used by thousands of practices across all 50 states. In early 2025 Medsender raised a $5M Series A led by Ballast Point Ventures while already cash-positive, and the company debuted on the 2025 Inc. 5000 at #550.
Cake is a New York-based startup that bundles the sprawling open-source AI stack into a single managed platform, so companies - especially in regulated industries like finance, insurance and healthcare - can deploy AI inside their own cloud without wiring together 100+ tools by hand. Founded in 2022 by Misha Herscu and Skyler Thomas and launched from stealth in December 2024 with a $13M seed led by Google's Gradient Ventures, Cake handles the integration, security, governance and cost-monitoring glue around open-source components like LangChain, Ray, MLflow and vector databases, all deployed inside a customer's own VPC so data never leaves.
Century Health is a New York-based health technology company that turns fragmented, messy electronic health record data into clean, structured, analysis-ready real-world evidence. Its AI-powered platform, CHARM (Century Health Abstraction & Retrieval Model), automates the curation, abstraction, and de-identification of clinical data to build disease-specific patient registries for pharmaceutical and life sciences research. Founded in 2023 by Vish Srivastava and Sanjay Hariharan, the company reports 97% accuracy against clinical expert judgment and raised a $5M seed round in 2026 led by Origin Ventures.
Clearpol is a San Francisco healthtech company that builds AI tools for post-acute and long-term care providers. Its platform reads a facility's clinical data and regulatory environment, then automates the paperwork nobody likes: drafting CMS Form 2567 Plans of Correction, flagging resident risk before it escalates, and answering questions about federal and state nursing-home regulations. Positioned as a compliance 'co-pilot' for skilled nursing facilities, Clearpol says it is trusted by 900+ long-term care facilities and has written thousands of Plans of Correction.
Credal.ai is a New York-based enterprise AI startup building a control plane for company AI agents. Founded in 2022 by two former Palantir engineers, its platform connects internal company data - from Google Drive and Slack to Salesforce - to large language models while strictly enforcing existing user permissions, redacting sensitive data, and logging every prompt and action. Credal lets regulated enterprises build, govern, and deploy AI agents and MCP servers without leaking data or breaking compliance rules.
Exactrx is a Nashville- and New York-based healthcare AI company that automates revenue cycle management for ambulatory surgery centers and outpatient providers. Its platform reads the operative note, codes the case, validates each charge against more than 80,000 payer rules with a tri-engine system, and generates a submission-ready claim in under 30 seconds - leaving humans to review and submit. Founded in 2024 by Athena Doshi and a clinician-and-engineer team, the company positions itself as access-to-care infrastructure rather than billing software, aiming to recover the revenue that denials and documentation gaps quietly drain from surgical facilities.
Feathery is a San Francisco software company that builds an AI operations platform for financial services. It started in 2021 as a developer-friendly, no-code form builder and has grown into a data intake and workflow automation platform that ingests, validates, and syncs client information across CRMs, custodians, and policy systems. Feathery pairs pixel-perfect forms and document generation with AI document intelligence, meeting and audio extraction, and collaborative approval workflows, targeting insurance carriers and brokers, wealth management firms, RIAs, and broker-dealers.
Lango is a technology-enabled language services company that unifies interpretation, translation, and language access into a single secure platform. Founded in 2016 and launched from Buenos Aires with $15K and a laptop, Lango connects organizations in healthcare, legal, education, and government to on-site, phone, video, and AI-driven interpreting and translation across 200+ languages, including American Sign Language. It serves more than 1,000 customers through its platform and a family of affiliated language companies.
Polytomic is a San Francisco data-movement company that unifies ETL, Reverse ETL, and CDC streaming in a single platform, letting teams keep data warehouses, databases, and SaaS tools in sync without maintaining brittle one-off pipelines. Founded in 2019 by former PlanGrid engineers Ghalib Suleiman and Nathan Yergler and backed by Y Combinator, it pairs a no-code interface for business teams with SQL, monitoring, and infrastructure-as-code controls for data engineers.
Quadrant Health builds AI voice and agentic workflows that run natively inside the electronic health records clinicians already use - Epic, athenahealth, eClinicalWorks and Medent. Founded in 2021 out of Y Combinator's Winter 2021 batch, the company started by analyzing EHR and messaging data to predict disease before it occurs, then pivoted into AI agents that handle the operational grind of a medical practice: an AI scribe that drafts EHR-ready notes in real time, and administrative agents that answer calls 24/7, book appointments, collect intake, process refill requests and close care gaps in 20+ languages. Led by co-founder and CEO Anin Sayana, Quadrant sells HIPAA- and SOC2-compliant software to providers, payers and life sciences organizations.
Salt AI is a Los Angeles contextual-AI company building a visual platform that lets regulated enterprises - especially life sciences and healthcare teams - orchestrate many AI models into governed, auditable workflows that run inside their own infrastructure. Founded in 2023 by former Myspace CTO Aber Whitcomb and Jim Benedetto, Salt lets biochemists and clinicians drag, drop, and chain models like AlphaFold2 (which Salt runs 22x faster), ProteinMPNN, and Chroma without writing code, turning months of pipeline engineering into weeks while keeping every prompt, weight, and response logged for compliance.
Sensible is a developer-first platform that turns any document - PDFs, scans, emails, images - into structured, verifiable JSON. It pairs LLM-based extraction with deterministic, layout-based rules written in its own configuration language, SenseML, and ships 150+ prebuilt parsers plus confidence scores, source coordinates, and human-review workflows. Founded in 2020 and backed by Craft Ventures, Sensible is used by companies across insurance, proptech, financial services, logistics, and healthcare to automate document-heavy operations.
Simple AI is a San Francisco startup building enterprise-ready voice AI agents that handle inbound and outbound B2C phone calls. Its agents answer questions, personalize offers, qualify leads, and close and upsell transactions over the phone - the company says they convert and upsell up to 30% more than trained human reps. Founded in 2024 by former Y Combinator software leads Catheryn Li and Zach Kamran, Simple AI runs on a proprietary voice stack with sub-850ms end-to-end latency and raised $14M in seed funding in February 2026.
Wald.ai is a Palo Alto-based context intelligence company that lets enterprises use generative AI assistants like ChatGPT, Claude, Gemini and Grok without leaking sensitive data. Its context-aware DLP engine uses specialized small language models to detect and redact confidential information in real time, then restores it in the response, giving regulated industries a governed, single-pane way to adopt AI without blocking it. Founded in 2023 by Vinay Goel and Ritesh Ahuja, the company closed a $4M seed round in December 2024.