Metrika is a Cambridge, Massachusetts SaaS company that built the first operational intelligence and risk management platform for blockchains and digital assets. It collects, analyzes, and visualizes the health of decentralized networks in real time - tracking hundreds of risk indicators across protocols, smart contracts, and market conditions - so that protocol teams, financial institutions, and regulators can monitor performance, detect issues early, and meet compliance obligations.
Pienso is a no-code AI platform that lets domain experts - not just engineers - train, fine-tune, and deploy their own machine learning and large language models without writing a single line of code. Founded by MIT Media Lab alumni Birago Jones and Karthik Dinakar, Pienso keeps humans in the loop and data in the customer's control, with cloud or on-premise deployment for governments, media companies, and regulated enterprises.
Shawn Manchester is the CEO of Triplebar, an Emeryville-and-Oakland based biotech building generative AI 'genome language models' paired with ultra-high-throughput phenotypic screening to slash the cost of biologic therapeutics and food proteins. A chemical engineer by training (BS Brown, PhD MIT), he was the lead scientist in the first AI-versus-human strain engineering contest at Zymergen before joining Triplebar in 2021, where he rose from VP of Product to COO to CEO in March 2025.
Sheldon J.J. Kwok is the CEO and co-founder of LASE Innovation, a Boston-area techbio company turning microscopic lasers into cellular barcodes. He spent his PhD at MIT and Massachusetts General Hospital building particles that emit pure laser light from inside living cells, then spun the work into a company aiming to give every cell a trackable identity and add a time dimension to flow cytometry.
Vishnu Jayaprakash is the CEO and co-founder of AgZen, an MIT spinout that puts cameras and AI on crop sprayers so farmers can see, for the first time, where their pesticide droplets actually land. He grew up spraying rice and mangoes by hand on his family's farm near Chennai, spent more than a decade at MIT studying how droplets cling to leaves, and turned that physics into a business that went from zero paid acres to nearly a million in two years. His pitch is blunt: agriculture has sprayed at scale for 80 years without ever measuring whether the chemical reached the plant.
Shabbir Dahod is the co-founder, President and CEO of TraceLink, the Massachusetts company that built the de-facto industry standard network for tracing pharmaceuticals from factory to patient. He started the company in 2009 out of ideas sparked at MIT, after earlier stints building multimedia and web products at Paul Allen's Asymetrix and Microsoft, and founding the serialization pioneer SupplyScape. Today he is pushing TraceLink's 291,000-entity digital network toward agentic AI and end-to-end supply chain orchestration, work that earned him a 2024 Pros to Know Lifetime Achievement Award.
Alec Nielsen is the co-founder and CEO of Asimov, a Boston synthetic biology company building computer-aided design tools for living cells. His MIT PhD work in the Voigt Lab produced Cello, a programming language that compiles plain-text logic instructions into thousands of DNA letters. Asimov turned that academic breakthrough into a commercial platform for designing and manufacturing biologics, cell therapies, and gene therapies, backed by Andreessen Horowitz, DARPA, and a $175M Series B led by CPP Investments.
Apurva Shrivastava is the co-founder and Co-CEO of Avoca, a New York AI company that builds voice and workflow agents for home services businesses like HVAC, plumbing, and roofing contractors. An MIT computer science graduate and second-time founder who built AI products at Apple and engineered at Retool, he and co-founder Tyson Chen pivoted from restaurants to the trades after a chance encounter at a Texas conference. By 2026 Avoca had crossed a $1 billion valuation, 800-plus customers, and $125M-plus raised from Kleiner Perkins, Meritech, and General Catalyst.
Andrew Lau is the co-founder and CEO of Jellyfish, the Boston company that pioneered the Engineering Management Platform - software that does for engineering organizations what Salesforce did for sales. An MIT-trained engineer who spent nine years running engineering at search pioneer Endeca, Lau reconnected with two former colleagues a decade later to build a tool that translates the work of software teams into language the business actually understands. Jellyfish has raised roughly $117M, tracks 600-plus engineering organizations, and sits at the center of the industry's loudest debate: how to measure what AI is really doing to software development.
Ayush Sharma is the founder and CEO of Warp, an AI-native employee management, payroll, and compliance platform built for high-growth startups. An MIT computer science and physics graduate and former Yelp ML engineer, he started Warp out of Y Combinator's Winter 2023 batch to fix the government red tape he hated as a distributed-team founder. Warp now runs payroll across all 50 US states and 150+ countries for hundreds of startups, and in June 2025 raised an $18M Series A led by Sound Ventures.
Bo Jiang is the co-founder and CEO of Lithic, the New York card-issuing platform that started life as the consumer privacy tool Privacy.com. He and two childhood friends built the burn-after-use virtual card people loved, then discovered the real prize was the issuer-processor plumbing underneath it. When developers started reverse-engineering Privacy.com's API to issue their own cards, Jiang turned the back end into the product, rebranded to Lithic, and now sells programmable money movement to high-growth companies.
Cameron Halliday is the co-founder and CEO of Mantel, a Cambridge, Massachusetts climate-tech company spun out of MIT's chemical engineering labs. Mantel uses molten borate salts to capture CO2 from heavy industry at high temperatures, recovering most of the energy as usable steam and slashing the cost and energy penalty of carbon capture. Halliday discovered the core material during his PhD at MIT, then co-founded the company in 2022 and raised a $30 million Series A co-led by Shell Ventures and Eni Next.
Carlos Garcia is the founder and CEO of Finhabits, a bilingual money app built to close the wealth gap for U.S. Latinos. An MIT-trained engineer who spent nearly two decades on Wall Street, he turned the realization that he once had no idea what a 401(k) was into a platform that lets people start investing for as little as $5 a week. Finhabits has grown to more than 800,000 members and earned recognition from Goldman Sachs and Fast Company.
Ege Akpinar is the founder and CEO of Pointr, the indoor location company behind Deep Location, a platform that gives buildings the kind of accurate blue-dot navigation people take for granted outdoors. He started it in 2013 as a Harrods consulting side project, turned it into a venue-mapping engine used by Fortune 100 companies, hospitals, airports and CES, and built an AI mapping system that compresses days of manual map-drawing into minutes.
Erik Duhaime is the cofounder and CEO of Centaur.ai (formerly Centaur Labs), a Boston startup that turns the wisdom of crowds into medical-grade training data for AI. His PhD research at the MIT Center for Collective Intelligence showed that ordinary medical students, when their opinions are measured and pooled the right way, can out-diagnose individual experts. He built a company on that insight, raising $35M total to label the world's health and science data.
Evangelos (Evan) Efstathiou is the CEO of Burmester & Vogel, a Boston-based maritime software company that turns the slow, paper-heavy work of laytime and demurrage calculation into AI-driven automation. An MIT-trained entrepreneur who has spent his whole career at the crossroads of shipping, software and capital markets, he bought the 40-year-old freight-tech firm in 2019 through a Series A and is rebuilding it into what he calls 'the Bloomberg of shipping.' He also runs the maritime M&A and strategy advisory Skysail Advisors, which he founded in 2016.
Ganesh Kaundinya is President and CEO of GlycoEra, a Swiss-US biotech building extracellular protein degraders to treat autoimmune disease. An MIT-trained chemical engineer, he co-founded Momenta Pharmaceuticals and helped grow it from a sugar-sequencing concept into a public company with FDA-approved products, later acquired by Johnson & Johnson for $6.5 billion. At GlycoEra he raised an oversubscribed $130 million Series B in 2025 to push a precision IgG4 degrader toward the clinic.
Gavin Cotter is the founder and CEO of Koala Health, a Boston-based digital pet pharmacy that delivers chronic pet medications through a mobile-first platform built to work directly with pet parents and their veterinarians. An MIT-trained mechanical engineer turned operations leader, he cut his teeth scaling PillPack's pharmacy operations before Amazon acquired it, then reassembled a core PillPack crew in 2021 to do for animals what PillPack did for people: make managing medications boring, easy, and reliable. Koala has since expanded to all 50 states and raised a $20M Series B led by Valspring Capital in 2025.
Harry Rein is the co-founder and CEO of ShopMy, the New York creator-commerce platform that turns taste into a paycheck. Trained as an AI engineer at MIT, he built ShopMy from a side project into a company valued at $1.5 billion, connecting roughly 200,000 creators with more than 1,200 brands and processing over $1 billion in annual transactions. He insists recommendations stay authentic, runs the company at profitability, and frames the next phase as a shift from the creator economy to the curator economy.
Jacob Donoghue is a physician-scientist and the co-founder and CEO of Beacon Biosignals, a Boston company applying machine learning to EEG brain data to build neurobiomarkers for psychiatric, neurological, and sleep disorders. Trained with an MD from Harvard Medical School and a PhD in neuroscience from MIT, he started Beacon in 2019 on the bet that decades of overlooked brainwave recordings could be turned into a precision-medicine engine for drug development and diagnosis. Under his leadership the company has raised over $116M, secured FDA clearance for a wearable EEG headband, acquired home sleep-testing firm CleveMed, and partnered with more than half of the world's top ten biopharma companies.
Josh Gruenstein is the co-founder and CEO of Tutor Intelligence, an MIT CSAIL spinout building AI-powered robots that work alongside people in American factories and warehouses. He leases robots by the hour instead of selling them, betting that fleet-scale learning, not bigger algorithms, is what finally puts a robot in every factory. In December 2025 the company raised a $34M Series A led by Union Square Ventures, bringing total funding to roughly $42M.
Josh Haimson is the co-founder and CEO of Inductive Bio, a New York based AI company building software to speed up small molecule drug discovery. Before starting Inductive in 2024 with Ben Birnbaum, Josh ran product for the machine learning and data curation teams at Flatiron Health, generating real-world evidence across a network of more than 2 million cancer patients. The company raised a $25M Series A in May 2025 led by Obvious Ventures, and its Compass platform helps chemists predict a molecule's ADMET properties before it is ever synthesized, attacking the 'whack-a-mole' bottleneck that slows drug development.
Katie Siegel is the co-founder and CEO of Flipturn, the New York software company building the control center for electric fleet and charger operations. An MIT-trained engineer who was among the first dozen builders at Samsara before its IPO and co-founded Impira (acquired by Figma), she now points her fleet-software expertise at the least glamorous, most consequential problem in electrification: keeping commercial EV chargers actually working. Flipturn has raised about $26.5M, including an $11M Series A led by CRV, and counts the City of Seattle, Purolator, Republic Services, and Swift Transportation among its customers.
Matthew Arbesfeld is the CEO and co-founder of LogRocket, the Boston-based frontend monitoring and product analytics company he built with his lifelong best friend Ben Edelstein. The two met as one-month-old infants on a parental playdate and have been building software together ever since. A Thiel Fellow who dropped out of MIT in 2015, Arbesfeld first launched a developer deployment tool called AppHub before pivoting to LogRocket, the 'DVR for bugs' that lets engineering teams replay exactly what users did before something broke. LogRocket has raised about $55 million total, monitors billions of user sessions, and in 2026 launched Ask Galileo, an AI layer that answers plain-English questions about user experience.
Mohit Rawat is the Boston-based CEO of Myricx Bio, a UK-US biotech building a first-in-class antibody-drug conjugate platform based on NMT inhibition to treat cancer. He arrived in September 2025 fresh off Fusion Pharmaceuticals' $2.4 billion sale to AstraZeneca, where he was President and Chief Business Officer. With a Harvard MBA, an MIT chemical engineering master's, and stints at Novartis, AbbVie and McKinsey, he is steering Myricx toward its first human clinical trials in 2026.
Parth Shah is the co-founder and CEO of Polimorphic, the New York-based company building AI-powered constituent relationship management software for local governments. An MIT-trained electrical engineer and former NVIDIA deep learning engineer, Shah started out trying to build an 'ESPN for politics' and ended up rewiring how town halls answer phones, process permits, and serve residents in 75+ languages. In July 2025 Polimorphic raised an $18.6M Series A led by General Catalyst, bringing total funding to roughly $28M.
Paul Monasterio is the CEO and co-founder of Kalepa, a New York AI company building decision-support software for commercial insurance underwriters. A Venezuelan-born nuclear physicist with a PhD from MIT, he traded particle research for big-data analytics at Applied Predictive Technologies (acquired by Mastercard for $600M) and Facebook before launching Kalepa in 2018. Its Copilot platform helps underwriters 'bind with confidence,' and the company raised a $14M Series A from Inspired Capital in 2021.
Sameer Shalaby is the Founder, President and Co-CEO of VersiFi, a New York digital-asset trading and lending firm that brings a TradFi-inspired, regulated approach to institutional crypto. A serial software entrepreneur with 25-plus years in financial technology, he has built and exited multiple companies - Paladyne Systems (acquired by Broadridge in 2011), Cogency Systems, and the publicly listed TenFold Corporation - and ran HazelTree Fund Services as President and CEO before launching VersiFi in 2022.
Samir Dutta is the co-founder and CEO of Farsight, a New York AI company that automates the grunt work of high finance - pitch decks, valuation models, CIMs and buyer lists - directly inside Excel and PowerPoint. An MIT graduate who did time at Evercore and General Atlantic before building the tool he wished he'd had, Dutta raised a $16M Series A led by SignalFire in 2025 and landed on the Forbes 30 Under 30 list in the AI category for 2026.
Steve Peltzman is the CEO of FeedbackNow, the company behind the smiley-face feedback buttons in airport bathrooms and security lines. A former U.S. Air Force officer who worked on the B-2 Stealth Bomber, a decade-long CIO of New York's Museum of Modern Art, and Forrester's first Chief Business Technology Officer, he spun FeedbackNow out of Forrester in September 2024 with a $9M Series A. He is turning a network of physical sensors and one-tap buttons into a real-time, AI-driven operating system for hospitals, convenience stores, airports and stadiums across 40 countries.