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Tagged: boston-biotech
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Founder · Executive · Scientist
Nan Ji
Nan Ji is co-founder, president and CEO of PAQ Therapeutics, a Burlington, Massachusetts clinical-stage biotech pioneering autophagosome-tethering compounds (ATTECs) to degrade KRAS and other 'undruggable' disease drivers. A Harvard-trained organic chemist with 30+ patent applications, he spent seven years at Novartis, helped build Kymera Therapeutics from seed stage as VP of Chemistry, and launched PAQ in 2020 to hijack the body's natural cellular clean-up machinery for cancer and neurodegenerative disease.
biotech · targeted-protein-degradationRead →
Health · Hardware
Fortitude Biomedicines
Fortitude Biomedicines is a Waltham, Massachusetts biotech that launched in early 2026 with $13M in seed financing to develop next-generation antibody-based therapies for autoimmune diseases and cancer. Its proprietary GLUE-DAC platform bolts molecular glue degraders onto antibody-drug conjugates, aiming to use catalytic targeted protein degradation to widen the therapeutic window of ADCs and overcome the resistance that has dogged the field. Its lead program, FORT-202, is a first-in-class T-cell targeting bispecific antibody for axial spondyloarthritis expected to reach the clinic in the first half of 2027.
biotech · biopharmaceuticalRead →
Health
Edgewood Oncology
Edgewood Oncology is a clinical-stage biotechnology company developing BTX-A51, a first-in-class oral small-molecule multi-kinase inhibitor that co-targets casein kinase 1 alpha (CK1α) and cyclin-dependent kinases 7 and 9 (CDK7/CDK9) - three master regulators of cancer cell survival and transcription. Founded by veteran biotech executive David N. Cook and emerging from stealth in March 2024 with $20M in Series A financing from Alta Partners, the company is advancing BTX-A51 through Phase 2a trials in relapsed/refractory acute myeloid leukemia and genetically-defined (GATA3-mutant) ER+/HER2- metastatic breast cancer.
oncology · biotechnologyRead →
Health · Enterprise
Granata Bio
Granata Bio is a Boston-based biopharmaceutical company building a portfolio of fertility and reproductive-health therapies. Founded in 2018, it in-licenses and develops medications used in IVF outside the US, runs its own clinical programs, and is expanding into ovarian biology. Its lead asset is an investigational human menopausal gonadotropin in the pivotal Phase III GRACE study, and its 2025 acquisition of Oviva Therapeutics added a first-in-class therapeutic aimed at extending ovarian function. The company targets the multi-billion-dollar global infertility medication market with the goal of expanding patient access and improving IVF outcomes.
fertility · ivfRead →