Azalia Mirhoseini is an Iranian-born AI researcher, Stanford professor, and co-founder of Ricursive Intelligence - a frontier AI lab valued at $4 billion that uses AI to design better chips, which in turn train stronger AI. Best known for AlphaChip, the deep reinforcement learning system that now designs Google's TPUs and has compressed chip floorplanning from months to hours, she also co-invented the Mixture-of-Experts architecture underpinning GPT, Claude, and Gemini. With 20,000+ citations and a $335M-funded startup launched in under four months, she is closing the recursive loop between artificial intelligence and the hardware it runs on.
Wardstone is a Y Combinator F25 defense startup building a global constellation of satellites equipped with space-based interceptors to kinetically destroy hypersonic and ballistic missiles. Founded by brothers Sebastian and Tobias Fischer, the company is pursuing America's Golden Dome initiative - a layered missile defense system that can engage threats in space before they reach US soil. With a $5M seed round and three successful automated intercept demonstrations during YC, Wardstone is positioning itself as a next-generation missile defense contractor targeting a $40B/year market.
Zeon Systems builds AI-powered robotic infrastructure that automates scientific laboratory experiments. Founded in 2025 by Brontë Kolar and Tahir D'Mello - both Forbes 30 Under 30 honorees who previously worked together at Latch Bio - the company uses off-the-shelf robotic arms paired with depth cameras and a natural language interface to let scientists describe experiments in plain English and have robots execute them autonomously. Already piloting at Stanford and UCSF, Zeon targets the multi-billion-dollar lab automation market by lowering the cost and complexity of scientific research - betting that cheaper automation means more experiments, and more experiments mean faster cures.
Matt Webb is a London-based designer, technologist, and product inventor who has spent 25+ years at the intersection of technology and ideas. Co-founder and former CEO of BERG (whose Little Printer became an IoT icon acquired by MoMA NY), former MD of R/GA's IoT accelerator, and author of the pop-neuroscience classic Mind Hacks, Webb now runs Acts Not Facts and co-founds Inanimate, making playful AI hardware like Poem/1 - a clock that writes a new rhyming poem every minute - while writing his blog Interconnected for over 25 years without stopping.
Michael Lynch is a bootstrapped solo founder who quit Google after seven years to build software and hardware businesses entirely on his own terms. He grew TinyPilot - a KVM-over-IP device built from a $100 Raspberry Pi kit - into a $1M/year business and sold it in 2024 for ~$600K. He writes with radical transparency about money, failure, and the craft of independent software development at mtlynch.io, and is now writing 'Refactoring English', a book on writing for software engineers.
Ryan Peterman went from new grad to Staff Engineer at Instagram in three years, then left one of tech's most coveted jobs to build what he wished existed. His newsletter 'The Developing Dev' has 106,000+ subscribers, his podcast 'The Peterman Pod' features career stories from top engineers, and his hardware company Compose is building an ultra-low-profile ergonomic keyboard. Based in San Francisco, he is the rare engineer who codes, writes, interviews Turing Award winners, and designs keyboards with equal intensity.
Zephyr Fusion is building the first in-orbit fusion power source - a compact, megawatt-class reactor designed to run in the vacuum of space. Founded by two physicists who met in grad school operating a spherical tokamak, the San Diego-based startup uses a levitated dipole magnetic confinement approach with high-temperature superconductors. Their bet: space makes fusion easier, not harder. With launch costs down 10x and mass-produced HTS tapes providing 10x more field per kilogram, Zephyr Fusion aims to power the industrial revolution that humanity is about to have off-planet.
Founders, Inc. (f.inc) is a 42,000 sq ft campus, community, and first-check fund at Fort Mason in San Francisco — built for the wildly ambitious founders solving hard problems at the edge of what's possible. Not a traditional VC and not a time-boxed accelerator, it combines pre-seed investment (up to $250K), a dedicated workspace with hardware labs and media studios, daily meals, and an indefinite community of 80+ builders. Founded in 2020 by serial builder Furqan Rydhan, it has backed 100+ companies across AI, AR/VR, Web3, and hardware — including thirdweb, buildspace, LiveKit, and Sync Labs. Featured in the Wall Street Journal and New York Times.