GlycanAge is a UK-registered, Croatian-founded longevity biotech that measures biological age by analyzing glycans - sugar molecules attached to immune-system antibodies. Built on roughly two decades of glycobiology research led by Professor Gordan Lauc, the company turns a finger-prick blood sample into a report on how fast a person is aging at the molecular level, plus a specialist consultation to guide lifestyle changes. It sells directly to consumers and is expanding its glycan biomarkers into hospitals and preventive-care systems.
PranaX is a Houston-based regenerative medicine biotechnology company developing stem cell-derived exosome products to counter aging, inflammation, and tissue damage. Built on exosome technology exclusively licensed from The University of Texas MD Anderson Cancer Center, PranaX operates an FDA-registered cGMP facility at the Levit Green life science campus and is bringing to market a physician-directed exosome wellness supplement (ExoWELL) and a personal exosome banking service (ExoSTORE). The company closed an oversubscribed $17M Series A in early 2026.
Human Longevity, Inc. is a San Diego- and South San Francisco-based genomics and precision-health company founded in 2013 by genome-sequencing pioneer J. Craig Venter, Peter Diamandis, and Robert Hariri. It pairs clinical-grade whole genome sequencing with whole-body MRI, hundreds of blood biomarkers, and AI analytics - delivered through its Health Nucleus platform - to detect cancer, cardiovascular disease, and other age-related conditions before symptoms appear. After a decade building one of the world's largest longitudinal genotype-phenotype datasets, the company in 2026 launched a $599 clinical-grade whole genome report and spun out Human Life Foundation Models, Inc. to build large-scale AI foundation models for longevity science.
InsideTracker is a Cambridge, Massachusetts personalized health and wellness company (legally Segterra, Inc.) that turns your blood, DNA, and wearable data into a science-backed action plan. Founded in 2009 by MIT-trained scientist Dr. Gil Blander, the platform analyzes dozens of blood biomarkers, estimates your biological 'InnerAge,' and recommends specific foods, supplements, and lifestyle changes to optimize performance, healthspan, and longevity. It has become a favorite of athletes and quantified-self enthusiasts and integrates directly with Garmin, Fitbit, Oura, and Apple devices.
OneSkin is a San Francisco biotech and direct-to-consumer skincare company founded by four Brazilian women scientists who set out to slow skin aging at the molecular level. Its flagship OS-01 peptide - identified from a library of 900+ candidates using computational screening and tested on lab-grown human skin models - targets senescent 'zombie' cells that drive wrinkles, thinning and loss of firmness. The company sells topical 'supplements' for the face, eyes, body and sun protection, and frames skin not as a cosmetic surface but as the body's largest organ and a lever on overall healthspan.
Rony Sellam is the CEO of InsideTracker, a Cambridge, Massachusetts based personalized-health company that uses blood biomarkers, DNA and lifestyle data to give consumers actionable recommendations for extending healthspan. A former Deloitte consultant from France by way of Geneva and a longtime healthcare IT executive, he has run InsideTracker for over a decade and helped push the company past 100,000 members and into partnerships with Oura and Fitness SF.
Generation Lab is a San Francisco longevity biotech building SystemAge, a diagnostic that measures how fast your body is actually aging rather than predicting a number. Using DNA methylation analysis of hundreds of biomarkers, it reports biological ages across roughly 19 organ systems from a blood sample, then hands clinicians an actionable plan to track whether interventions are moving the needle. Founded in 2023 by CEO Alina Rui Su, UC Berkeley aging researcher Dr. Irina Conboy, and operator Michael Suswal, the company raised an $11M seed in October 2025 led by Accel and works with 275+ clinics across roughly 18 countries.
Mitrix Bio is a Bay Area biotech startup building bioreactor-grown mitochondria - the cell's power plants - packaged into vesicles it calls 'Mitlets' and delivered by injection. Founded by former SLAC accelerator manager Tom Benson, the company treats the slow decline of mitochondria as a root cause of aging and aims to manufacture autologous, young mitochondria at industrial scale so clinicians can regenerate organs, boost immunity and cognition, and extend healthy human lifespan toward 130 years.
Rejuvenation Technologies is a Stanford-spun biotech developing modified-mRNA therapeutics that temporarily switch on telomerase to lengthen telomeres and reverse cellular aging in specific tissues. Its lead programs target fibrotic and age-related diseases such as pulmonary fibrosis, chronic liver disease and bone-marrow failure, delivered by proprietary tissue-targeted lipid nanoparticles. Backed by Khosla Ventures and Y Combinator, the company holds 50+ patents and is advancing toward Phase I clinical readouts.

Katie Hanson is a strategic operator at the seam between health, AI, and regenerative systems. As Chief Business Officer at Wonder Sciences, she helps move next-generation mental healthcare protocols from research into the real world; as Partner at The Liminal Collective and advisor to organizations from Oceanic Global to Earth 300, she works across the rare overlap of healthspan, climate, and frontier technology.
Alina Su is the co-founder and CEO of Generation Lab, a San Francisco longevity startup building an at-home cheek-swab test that measures biological age across organs and systems. She got her first medical device patent at 15, founded the needle-free injection company NovaXS, left a Harvard Medical School PhD to commercialize aging science from UC Berkeley's Conboy Lab, and made Forbes 30 Under 30 in 2023. Generation Lab has raised about $11M and counts geneticist George Church and Aubrey de Grey among its advisors.
Tune Therapeutics is a genetic-medicine company building tools to turn genes up or down without cutting DNA. Its TEMPO epigenetic-editing platform tunes gene expression the way a sound engineer rides a fader - reversible, programmable, and precise. Spun out of Duke's Gersbach Lab, Tune raised over $175M in Series B financing in January 2025 and is running first-in-human trials of TUNE-401, an epigenetic silencer for chronic hepatitis B, with the larger ambition of editing the genome's software to extend human healthspan.
Bold is a Los Angeles-based digital healthy-aging company that delivers personalized, clinically validated exercise, nutrition, and virtual-care programs to older adults. Available at no cost to roughly 12 million Medicare members through partnerships with Medicare Advantage plans and provider groups, Bold treats movement as medicine: its programs have been shown to reduce falls by up to 46%, increase weekly physical activity by 182%, and earn 91% member satisfaction. Founded by Amanda Rees and Hari Arul, the company has raised $27 million from investors including Andreessen Horowitz, Khosla Ventures, and Rethink Impact.
Amanda Rees is the co-founder and CEO of Bold, a Los Angeles based digital fitness platform that delivers personalized, science-based exercise programs to help older adults build strength, ease pain, and prevent falls. A Princeton-trained chemical and biological engineer who is also a longtime dance and tai chi instructor, Rees built Bold after spending most of her twenties caring for her grandmother and discovering how few preventive tools existed for aging well. Bold partners with Medicare Advantage plans and has raised about $27 million in total funding, including a $17 million Series A.
Retro Biosciences is a clinical-stage longevity biotech in Redwood City, California with a single, unsubtle goal: add ten healthy years to the human lifespan. Founded in 2018 and launched publicly in 2021 with $180 million from OpenAI CEO Sam Altman, the company attacks aging at the cellular level across three platforms - autophagy enhancement, cellular reprogramming, and plasma-inspired therapeutics. Its lead drug, RTR242, an autophagy-restoring small molecule aimed at Alzheimer's disease, entered a first-in-human Phase 1 trial in 2025. A 2026 raise valued Retro at $1.8 billion.

Dugal Bain-Kim is the co-founder and CEO of Lifeforce, a clinically integrated health optimization platform he launched in February 2022 with Tony Robbins, Dr. Peter Diamandis and Joel Jackson. An Australian-born finance and healthcare operator who went from BlackRock and Cambridge to telehealth, he built Lifeforce after his own fragmented hunt for answers about his changing body at 38. The company tests 40+ biomarkers via at-home blood draws and pairs the data with clinicians, coaching and supplements, on a stated mission to extend healthy lifespan for five million people by 2030.

Joe Betts-LaCroix is the co-founder and CEO of Retro Biosciences, a San Francisco longevity biotech on a mission to add 10 healthy years to the human lifespan. A scientist-turned-serial-entrepreneur who once held a Guinness World Record for building the world's smallest Windows PC, he now leads a company backed by OpenAI's Sam Altman, valued at $1.8 billion in 2026, that has run an Alzheimer's clinical trial and co-developed a longevity-focused AI model with OpenAI. He came to biology by an unlikely route: a D-average high schooler who tinkered in shared houses, then earned straight A's, transferred to Harvard, and did research at MIT and Caltech before co-discovering principles of electron transfer in proteins.
Hone Health is a New York-based telemedicine clinic built for preventive and longevity care. It pairs at-home and in-person testing of 40+ biomarkers with physician-guided treatment plans for hormone optimization, menopause, weight loss, sexual health, thyroid and more, delivered nationwide on a subscription model starting around $129/month. After raising a $33M Series A in January 2025 and acquiring in-home care company ivee, Hone has tested 300,000+ patients and treats roughly 55,000 active members.
Maxim (Max) Kholin is the co-founder and COO of Gero, a physics-powered longevity biotech company applying statistical physics and AI to crack the biology of aging. With roots in contract law, international business, and computational drug design, he bridges the gap between cutting-edge science and real-world commercialization. Gero - which he co-founded with physicist Peter Fedichev in 2015 - has pioneered the field of 'Gerophysics,' trained its models on 100M+ longitudinal medical records, and secured partnerships with Pfizer and Chugai Pharmaceutical worth up to $250M in milestones. Based across Singapore and Palo Alto, Kholin's mission is nothing less than transforming humans into a non-aging species.

Peter H. Diamandis is a Greek-American entrepreneur, physician, and futurist who has founded or co-founded 25+ companies and is best known as the creator of the XPRIZE Foundation - which has launched over $600 million in incentive competitions catalyzing $10+ billion in R&D. A data-driven optimist, he co-founded Singularity University with Ray Kurzweil, runs the Metatrends newsletter (157,000+ subscribers), and is a 4x New York Times bestselling author. His current mission centers on longevity - he launched the $101 million XPRIZE Healthspan in 2024 and published the Longevity Guidebook in January 2025.