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Tagged: 15-pgdh
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Epirium Bio
Epirium Bio is a San Diego-based clinical-stage biopharmaceutical company developing orally available small molecules that target PGE2 signaling to restore tissue homeostasis, reduce inflammation, and stimulate regeneration. Its lead candidate, MF-300, is a first-in-class oral 15-PGDH enzyme inhibitor advancing toward a Phase 2b trial for sarcopenia, the age-related loss of muscle strength for which no FDA-approved therapy currently exists.
biotech · biopharmaceuticalRead →
Executive · Investor · Operator
Alexander Casdin
Alexander Casdin is the Chief Executive Officer of Epirium Bio, a San Diego biotechnology company developing small-molecule therapies to improve muscle function. A healthcare executive and institutional investor with more than 25 years in the industry, he stepped up from CFO and COO to CEO on January 1, 2025, the same month Epirium's lead drug MF-300 - a first-in-class oral 15-PGDH inhibitor for sarcopenia - cleared the FDA to begin human trials. Before Epirium he founded and ran Reneo Capital Management, was CFO of Sophiris Bio, and ran VP of Finance at Amylin Pharmaceuticals, and he sits on the board of Erasca as audit committee chair.
alexander casdin · alex casdinRead →