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biotech1 claudin-11 antibody-drug-conjugates1 adc1 monoclonal-antibodies1 fibrosis1 oncology1 kidney-fibrosis1 liver-fibrosis1 lung-fibrosis1 idiopathic-pulmonary-fibrosis1 solid-tumors1 lixudebart1 clinical-stage1

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Allschwil (Basel)

CompanyHealthVc

Alentis Therapeutics

Alentis Therapeutics is a Swiss clinical-stage biotech built around a single, unusual biological target: Claudin-1 (CLDN1), a tight-junction protein that becomes exposed in both fibrotic tissue and solid tumors. Founded in 2019 on the discovery of physician-scientist Professor Thomas Baumert, the company develops first-in-class monoclonal antibodies and antibody-drug conjugates that bind exposed CLDN1 to reverse organ fibrosis and treat CLDN1-positive cancers. Headquartered in Allschwil near Basel with R&D roots in Strasbourg, Alentis has raised roughly $365 million across rounds, including a $181.4 million Series D in November 2024, and is running clinical trials for its lead antibody lixudebart (ALE.F02) and two ADCs, ALE.P02 and ALE.P03.

Allschwil (Basel)HQ

approx. $79 million combined (estimate to reach ~$365.6M total)Earlier rounds (Series A/B)

biotechclaudin-1cldn1antibody-drug-conjugatesadcmonoclonal-antibodies