clinical-data
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InteropX Sold the Plumbing: How a Five-Person Health-Data Company Made Stale Records Useful
Health plans had APIs, repositories and a stubborn problem: the records still arrived stale, duplicated or trapped in documents. InteropX built the virtual pipe between payers and providers, priced retrieval as low as $1 a chart, and eventually sold the system to Onyx.
InsiteOne Put Medical Images in the Cloud Before the Cloud Had a Name
The Connecticut company bet on off-site medical-image archiving in 1999, survived two giant owners, then returned with a broader plan: make radiology data portable, resilient and useful without forcing hospitals into another proprietary corner.
The Most Expensive Vial in a Clinical Trial Is the One Nobody Can Find
QuartzBio built a business around a stubborn problem in drug development: the sample is physical, the evidence is digital, and the two have a habit of losing track of each other. Its software tries to reconnect the chain before a missing vial or mismatched record becomes a costly trial delay.
Medpace
The Cincinnati CRO built a $2.5 billion business by taking on clinical trials that young biotechs cannot run alone - and by keeping the scientists, software, labs and logistics under one roof.
Astraea
Astraea is a San Francisco startup building an AI-native operating system for clinical trial biometrics. Its agentic platform turns raw study data and a protocol into FDA-ready outputs - SDTM and ADaM datasets, TFLs, and submission packages - compressing work that normally takes months into days while keeping humans in the loop for review and regulatory sign-off. Founded in 2026 by Stanford's Joshua Wang and Sanmay Sarada, the company is part of Y Combinator's Spring 2026 (P26) batch.
Frekil
Frekil is an AI-powered real-world evidence (RWE) platform for life sciences that turns raw clinical data - EHR, claims, and registries - into regulatory-grade evidence in minutes instead of months. Its agentic pipeline runs the full study lifecycle, from literature review and cohort building through statistical analysis plan generation and final reports, while keeping clinical data isolated from AI models. Founded in 2025 by IIT Bombay alumni Nikhil Tiwari and Shivesh Gupta, Frekil is a Y Combinator (X25/P25) company serving pharma, biotech, CROs, and academic researchers.
David Lazerson
David Lazerson is the co-founder and CEO of Briya, a healthcare technology company that connects hospitals, research institutions, and life sciences organizations so they can share de-identified, real-world patient data securely and in compliance with U.S. and European privacy rules. A physicist and cognitive scientist by training and a former Israeli military cyber operations officer, Lazerson built Briya on cryptography, federated learning, and zero-knowledge proofs, and in 2025 launched Briya AIRE, a clinical-grade AI research assistant that lets researchers ask questions in plain language instead of writing code.
Predoc
Predoc is a New York-based, clinician-founded startup building an AI-native platform for health information management. It automates the retrieval, cleaning, and structuring of patient medical records - pulling data from digital sources, faxes, and direct provider requests - and turns fragmented, unstructured documents into normalized, actionable data that plugs into existing clinical and research systems. Founded in 2022, the company raised $30M (Series A led by Base10 Partners) and serves oncology groups, research networks, and virtual care providers.
Redox
Redox is a Madison, Wisconsin-based healthcare technology company that runs a cloud network for exchanging clinical and administrative data between health systems, digital health vendors, payers, and life sciences companies. Founded in 2014 by three former Epic Systems engineers, Redox lets a customer connect once to a single API and then reach thousands of healthcare organizations across dozens of electronic health record systems, rather than building and maintaining hundreds of point-to-point integrations. The platform handles standards like HL7v2, CCD, X12, and FHIR, and processes billions of data transactions a year.
Nishant Hari
Nishant Hari is the founder and CEO of Predoc, a New York-based AI-native platform for health information management that retrieves, structures, and analyzes patient medical records for hospitals, oncology practices, and clinical trials. In September 2025 the company disclosed $30 million in combined seed and Series A funding led by Base10 Partners, with Northzone, Eniac, ERA, and angel investors from Flatiron Health, Datavant, Thirty Madison and Blackstone. Predoc reports 700% year-over-year revenue growth and cuts record retrieval times by up to 75% for customers like The Oncology Institute.
Century Health
Century Health is a New York-based health technology company that turns fragmented, messy electronic health record data into clean, structured, analysis-ready real-world evidence. Its AI-powered platform, CHARM (Century Health Abstraction & Retrieval Model), automates the curation, abstraction, and de-identification of clinical data to build disease-specific patient registries for pharmaceutical and life sciences research. Founded in 2023 by Vish Srivastava and Sanjay Hariharan, the company reports 97% accuracy against clinical expert judgment and raised a $5M seed round in 2026 led by Origin Ventures.
Vish Srivastava
Vish Srivastava is the co-founder and CEO of Century Health, a New York based AI company turning the messy, unstructured clinical notes buried inside electronic health records into structured, analyzable real-world evidence. Century's abstraction engine, CHARM, reads doctors' notes and pathology reports and pulls out clinical variables with 97% validated accuracy while keeping traceability back to the source document. The company focuses on therapeutic areas like gastroenterology, neurology, and rheumatology, and raised an oversubscribed $5M seed round in May 2026 led by Origin Ventures. Srivastava's pitch is simple and stubborn: the data needed to accelerate medical breakthroughs has already been collected during patient care; it just needs to be made accessible and actionable.
PointCross Life Sciences
PointCross Life Sciences is a Foster City, California software and services company that turns the messy data of drug development into FDA-ready submissions. Through its XBIOM platform and eDataValidator, it standardizes nonclinical and clinical study data to CDISC SEND, SDTM and ADaM formats, runs a Hadoop-based data repository for sponsors, and supplies the U.S. FDA itself with the software reviewers use to read nonclinical submissions. The company quietly powers roughly a quarter of all FDA SEND submissions.
Verantos
Verantos is a Menlo Park healthcare technology company that turns messy, fragmented patient records - including the clinical notes most platforms ignore - into research-grade real-world evidence (RWE) at scale. Using AI applied to the complete patient record and a rigorous focus on measured accuracy, completeness, and traceability, Verantos helps pharmaceutical companies, regulators, and health systems generate evidence that can hold up to FDA-grade scrutiny across every therapeutic area.
Tempus AI
Tempus AI is a Chicago-based health technology company that has built one of the world's largest libraries of clinical and molecular data, paired with an AI operating system that helps physicians and researchers make data-driven decisions in oncology, cardiology, radiology, and beyond. Founded in 2015 by Groupon co-founder Eric Lefkofsky after his wife's cancer diagnosis, the company sequences patient genomes, structures messy clinical records, and turns that data into diagnostics and AI tools used across a majority of U.S. academic medical centers. It went public on Nasdaq in June 2024 under the ticker TEM.
Anthony Costello
Anthony Costello is the CEO of Medidata Solutions, a Dassault Systèmes company, and one of clinical research technology's most seasoned architects. With nearly 30 years in the field, he started as a data manager at Genentech, co-founded two companies (Nextrials and Mytrus), and was acquired by Medidata before rising to lead it. Today he oversees over 8,000 active clinical studies globally each year, championing AI-driven trial innovation, decentralized models, and patient-centric design at the White House Clinical Trials Forum and beyond.
Caresyntax
Caresyntax is an AI-powered surgical intelligence platform that turns the operating room into a connected data environment. Its vendor-neutral software captures video, device, and EMR data across more than 4,000 ORs and supports over two million procedures a year, helping hospitals improve outcomes, reduce costs, and make surgery measurably safer.
Brent Dover
Brent Dover is the CEO of Carta Healthcare, an AI-powered clinical data management platform that serves hospitals and health systems nationwide using a 'Hybrid Intelligence' model combining AI with human expert abstractors. With over 20 years of healthcare technology leadership, Dover has presided over company-defining exits and growth events - including leading Medicity to a $500M acquisition by Aetna generating 16x investor returns, scaling Health Catalyst toward a NASDAQ IPO, and growing Commure to a $3.5B valuation. He joined Carta Healthcare in December 2023 and has since driven 2x revenue growth, 100% customer retention, and a $18.25M Series B1 round led by UPMC Enterprises.