Alexey 'Alex' Lugovskoy is the co-founder and CEO of Diagonal Therapeutics, a Watertown/Cambridge, Massachusetts biotech building 'clustering' antibodies that switch cellular signaling back on rather than block it. A Harvard-trained biophysicist who left physics after deciding green leaves were more interesting than tau neutrinos, he spent two decades in antibody R&D at Biogen, Merrimack, Morphic, and Dragonfly before launching Diagonal in 2022. He has co-invented an FDA-approved cancer drug, authored more than 100 patents and papers, and edits the antibody journal mAbs. In January 2026 Diagonal closed an oversubscribed $125M Series B co-led by Sanofi Ventures and Janus Henderson to push its lead program, DIAG723, into human trials for hereditary hemorrhagic telangiectasia.
Joe Betts-LaCroix is the co-founder and CEO of Retro Biosciences, a San Francisco longevity biotech on a mission to add 10 healthy years to the human lifespan. A scientist-turned-serial-entrepreneur who once held a Guinness World Record for building the world's smallest Windows PC, he now leads a company backed by OpenAI's Sam Altman, valued at $1.8 billion in 2026, that has run an Alzheimer's clinical trial and co-developed a longevity-focused AI model with OpenAI. He came to biology by an unlikely route: a D-average high schooler who tinkered in shared houses, then earned straight A's, transferred to Harvard, and did research at MIT and Caltech before co-discovering principles of electron transfer in proteins.
Nicholas Geisse is the CEO of Curi Bio, a Seattle biotech building human-relevant tissue platforms that make lab-grown muscle and heart cells behave more like the real thing. A Cambridge-trained pharmacologist who learned to wire up tiny instruments in Kevin Kit Parker's cardiac engineering lab at Harvard, he spent years at Asylum Research selling and designing atomic force microscopes before joining Curi Bio as Chief Science Officer in 2017. He led development of the Mantarray 3D engineered-muscle-tissue platform and the company's NIH-backed R&D program, then stepped up to chief executive in 2023. His work has collected an Xconomy 'Big Idea' award, an SBA Tibbetts award, and an Edison Award.
Valerie Daggett is a University of Washington bioengineering professor turned biotech founder who spent three decades running the world's largest collection of protein-folding simulations, stumbled onto a structure nature was not supposed to make, and built a company around it. As founder and CEO of Seattle-based AltPep, she is commercializing the alpha-sheet: a strange protein geometry her lab predicted on a computer before anyone confirmed it in a test tube. Her SOBA-AD blood test, which spots toxic amyloid oligomers years before symptoms, earned FDA Breakthrough Device Designation and put her at the front of the race to catch Alzheimer's early.
Olgica Bakajin is the CEO and Founder of Porifera Inc., a San Leandro, California-based company pioneering forward osmosis membrane technology for the food, beverage, and industrial water sectors. A physicist by training - B.A. from the University of Chicago and Ph.D. from Princeton - she spent nearly a decade at Lawrence Livermore National Laboratory developing carbon nanotube membranes that move water 1,000x faster than conventional materials. Her 2006 Science paper on carbon nanotube desalination became the most-cited chemistry article in the journal. In 2009 she spun Porifera out of LLNL, and the company now serves 100+ customers across 20+ countries, helping breweries, coffee roasters, and winemakers concentrate their products without heat, preserving flavor, aroma, and nutrients while slashing energy use by up to 80%.
Bryan Faust, PhD is an Investment Partner on the Bio + Health team at Andreessen Horowitz (a16z), where he backs seed and Series A companies at the intersection of biology and technology. A trained biophysicist with a PhD from UCSF, he published research in Nature, Science, and Cell before pivoting to venture—studying antibody-protein interactions, GPCR signaling, and COVID-19 nanobodies along the way. At a16z he has co-led investments in Stipple Bio, Tessera Labs, Gate Bioscience, and Formation Bio, and writes widely on AI in life sciences, biotech financing, and the coming era of programmable medicine. When he's not reading pitch decks, he's surfing, roasting coffee, or hunting down the perfect tacos al pastor.
Dario Amodei is the co-founder and CEO of Anthropic, the AI safety company behind Claude. A former VP of Research at OpenAI and co-inventor of Reinforcement Learning from Human Feedback (RLHF), he holds a PhD in biophysics from Princeton and has co-authored some of the most cited papers in AI safety and scaling laws. He leads Anthropic — valued at $380 billion as of early 2026 — with the conviction that building safe, interpretable AI is not only compatible with building powerful AI, but inseparable from it. His landmark essay 'Machines of Loving Grace' envisions AI compressing decades of scientific progress into years, potentially eliminating most disease and radically expanding human prosperity.