Arielle 'AZ' Zuckerberg is a General Partner at Long Journey Ventures, a San Francisco seed firm that backs the 'magically weird' - founders pursuing unconventional ideas at the earliest stages. A former product manager turned investor with stops at Wildfire Interactive, Google, Humin, Kleiner Perkins, and Coatue, she pairs a product-first lens with a hands-on, founder-friend approach. In March 2025 the firm announced a $181.8M fund (the number nods to chai - 18, life).
Don Vaughn, Ph.D. is the Co-Founder and CEO of Ampa Health, a Palo Alto-based neurotechnology company building FDA-cleared portable TMS (transcranial magnetic stimulation) devices that compress 36 days of depression treatment into a single day. A Stanford-educated physicist turned UCLA neuroscientist, Vaughn has built a career at the intersection of brain science, machine learning, and accessibility - detoured, notably, through a DJ career that landed him a #28 iTunes Dance chart hit featuring Nick Lachey. His TEDx talk on neurohacking has surpassed one million views. Ampa raised an oversubscribed $8.5M pre-A round in October 2025, achieved FDA clearance for its Ampa One device in February 2025, and is targeting 5,000 patient remissions by end of 2026 - with a long-term audacious goal of a billion remissions in ten years.
Anish Acharya is a General Partner at Andreessen Horowitz (a16z) who led the firm's consumer fintech and consumer AI investing for five-plus years before announcing his departure in 2025/2026 to build again. A University of Waterloo computer engineering grad, he co-founded SocialDeck (acquired by Google in 2010) and Snowball (acquired by Credit Karma in 2015), where he then rose to GM overseeing a platform of 100M+ members. Known for coining the 'Era of Abundance' consumer AI thesis, writing 'Disposable Software,' and spending weekends spinning deep house records under his DJ alias 'illscience,' Acharya occupies a rare space where operator intuition, engineering rigor, and cultural ear collide.
Justin Kan is a serial entrepreneur and investor best known as the co-founder of Twitch, the live streaming platform acquired by Amazon for $970 million in 2014. A Yale graduate who studied physics and philosophy, Kan pioneered lifecasting by wearing a camera 24/7 for Justin.tv in 2007, which evolved into Twitch and revolutionized gaming culture. He's launched multiple ventures including Socialcam (sold to Autodesk for $60M), served as a Y Combinator partner, and now invests through Goat Capital while building new companies in Web3, commerce, and music. Despite selling Twitch for nearly $1 billion, Kan has been candid about struggles with happiness, anxiety, and finding fulfillment beyond exits, making him a rare voice of authenticity in Silicon Valley's success-obsessed culture.