Acute Myeloid Leukemia

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oncology1 biotechnology1 btx-a511 ck1-alpha-inhibitor1 cdk7-inhibitor1 cdk9-inhibitor1 multi-kinase-inhibitor1 aml1 breast-cancer1 gata3-mutant1 precision-oncology1 clinical-stage-biotech1 apoptosis1 liposarcoma1

Tagged: acute-myeloid-leukemia

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Edgewood Oncology

Edgewood Oncology is a clinical-stage biotechnology company developing BTX-A51, a first-in-class oral small-molecule multi-kinase inhibitor that co-targets casein kinase 1 alpha (CK1α) and cyclin-dependent kinases 7 and 9 (CDK7/CDK9) - three master regulators of cancer cell survival and transcription. Founded by veteran biotech executive David N. Cook and emerging from stealth in March 2024 with $20M in Series A financing from Alta Partners, the company is advancing BTX-A51 through Phase 2a trials in relapsed/refractory acute myeloid leukemia and genetically-defined (GATA3-mutant) ER+/HER2- metastatic breast cancer.

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