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Tagged: off-the-shelf
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Health · Hardware
Mirror Biologics, Inc.
Mirror Biologics is a clinical-stage, international biopharmaceutical company developing an 'off-the-shelf' class of immunotherapy built on living, non-genetically-manipulated immune cells. Its patented Mirror Effect platform - protected by more than 200 issued patents - powers a pipeline led by AlloStim for cancer, AlloPrime as a universal anti-viral vaccine for the elderly, and StimVax as a neoantigen vaccine. Headquartered in Tampa, Florida with GMP manufacturing in Jerusalem and clinical operations across Thailand and Malaysia, the company is advancing AlloStim into late-stage trials, including a Phase II metastatic colorectal cancer study run in collaboration with Merck KGaA.
immunotherapy · biotechRead →
Health · Enterprise
AvenCell Therapeutics
AvenCell Therapeutics is a clinical-stage cell therapy company building switchable, universal CAR-T treatments that can be turned 'off' and 'on' even after they are inside a patient. By pairing this controllable switch with a CRISPR-engineered, off-the-shelf allogeneic platform, AvenCell aims to widen the narrow safety window of conventional CAR-T while cutting the cost and wait time of manufacturing, targeting hard-to-treat blood cancers like AML, B-cell malignancies and, increasingly, autoimmune disease.
biotechnology · cell-therapyRead →
Executive · Operator · Scientist
Kumar Srinivasan
Kumar Srinivasan is the President and CEO of Wugen, a St. Louis clinical-stage biotech building off-the-shelf memory NK and CAR-T cell therapies for cancer. A chemist turned dealmaker, he spent 25+ years in pharma and biotech business development, most notably engineering the partnering strategy at Turning Point Therapeutics that culminated in its $4.1 billion acquisition by Bristol Myers Squibb. Since taking Wugen's helm in March 2023, he has steered its lead programs WU-CART-007 and WU-NK-101 into pivotal and early clinical trials.
kumar srinivasan · wugenRead →