Beacon Biosignals is a Boston-based neurotechnology company that pairs FDA-cleared wearable EEG hardware with AI to turn brain electrical activity - especially during sleep - into scalable, at-home neurodiagnostics. Its platform powers drug development, clinical trials, and precision medicine across neurology, psychiatry, and sleep medicine.
Hinge Health is a San Francisco-based digital health company that delivers virtual care for musculoskeletal (MSK) and pelvic health conditions. It pairs an AI computer-vision motion engine (TrueMotion), an FDA-cleared wearable pain-relief device (Enso), and a remote clinical care team of physical therapists and health coaches to treat back, joint, and pelvic pain without relying on surgery or opioids. Sold mainly to employers and health plans as a benefit, it reached roughly 2,250 enterprise clients, surpassed 1.5 million lifetime members, and went public on the NYSE in May 2025 under the ticker HNGE.
ŌURA makes the Oura Ring, a titanium smart ring that reads sleep, recovery, heart rate, temperature and activity from the finger. Founded in Oulu, Finland in 2013 and now co-headquartered in San Francisco, it has shipped more than 5.5 million rings, surpassed $500M in 2024 revenue and reached an $11B valuation in its 2025 Series E.
Avi Schiffmann is a 23-year-old American technologist and founder who first went viral at 17 when his hand-built COVID-19 tracker hit 36 million daily users. He dropped out of Harvard after one semester, built Ukraine Take Shelter to house 100,000 refugees, then bet nearly his entire $2.5M seed round on a single domain - spending $1.88M on friend.com. His company Friend makes a $99 AI pendant that listens to your life and texts back like a companion, sparking a national debate about loneliness, surveillance, and what it means to connect.
Nathan Xu (also known as Xu Gao) is the co-founder and CEO of Plaud AI, the company behind the world's best-selling AI voice recorder and notetaker. A serial entrepreneur who failed three times before hitting gold, Xu bootstrapped Plaud from a Kickstarter campaign in 2023 to $180M+ ARR by 2025 - without a single dollar of venture capital. His credit-card-sized Plaud Note and wearable NotePin devices, which transcribe, summarize, and analyze conversations in 112 languages, have shipped to over 1.5 million users in 170+ countries. Based in San Francisco with roots in Wuhan, China, Xu represents a new breed of transpacific founder betting that the next great hardware platform fits in your pocket - or around your neck.
O-Boy is the world's first satellite-connected emergency rescue smartwatch, built for adventurers and professionals who operate beyond cellular coverage. Designed by Belgian studio Futurewave for startup LifeLineSat, it lets you send GPS-pinpointed rescue signals, custom messages, or live location tracking directly via satellite - no phone required. Think of it as the emergency button the wilderness has always needed, worn on your wrist.
Shokz OpenFit Pro are open-ear earbuds that pull off something most audiophiles thought impossible - noise reduction without sealing your ears. Launched at CES 2026, they combine a SuperBoost dual-diaphragm driver, Dolby Atmos with head tracking, 50 hours of battery life, and a triple-microphone array that quietly tamps down background noise while keeping you aware of your surroundings. Built for athletes, office workers, and anyone who refuses to sacrifice situational awareness for sound quality.