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Tagged: parkinsons-disease
4 resultsSort
Company
Company
Company
Legend
Health · Ai
Brenig Therapeutics
Brenig Therapeutics is a neurology-focused biotechnology company building disease-modifying small-molecule therapies for Parkinson's disease and other neurodegenerative disorders. Founded in 2021 and backed by $65 million in Series A funding led by NEA, Brenig pairs AI- and machine-learning-driven discovery with structure-based design to engineer brain-penetrant molecules that hit the central nervous system while sparing the rest of the body. Its lead candidate, BT-267, is a selective LRRK2 inhibitor now in human trials, followed by BT-409, a brain-selective NLRP3 inflammasome inhibitor targeting neuroinflammation.
parkinsons-disease · neurodegenerative-diseasesRead →
Health
Oryon Cell Therapies
Oryon Cell Therapies is a Belmont, Massachusetts clinical-stage biotechnology company developing autologous neuron replacement medicines for Parkinson's disease and other neurodegenerative disorders. Spun out of research at the Neuroregeneration Research Institute at McLean Hospital and Harvard Medical School, Oryon converts a patient's own blood cells into induced pluripotent stem cells, then differentiates them into dopamine-producing A9 neurons that are implanted into the brain to restore lost dopaminergic function - without immune suppression. The company emerged from stealth in March 2026 with a $21M Series A tranche ($42M total in equity and grants) and early Phase 1b/2a data showing motor improvements and neuroimaging evidence of restored dopamine signaling.
biotechnology · cell-therapyRead →
Health
Vima Therapeutics
Vima Therapeutics is a Cambridge, Massachusetts clinical-stage biotechnology company developing VIM0423, a potential first-in-class once-daily oral therapy for isolated dystonia and Parkinson's disease. The drug selectively targets muscarinic cholinergic receptors in the brain to correct the dopamine-acetylcholine imbalance underlying these movement disorders. Incubated at Atlas Venture and led by neurologist Bernard Ravina, the company emerged from stealth in 2025 and has raised a $100 million Series A.
biotech · neuroscienceRead →
Founder · Executive · Scientist
Ron Cohen
Ron Cohen, M.D., is a biotech entrepreneur with a 30-year record of building companies that ship medicines for the nervous system. He founded Acorda Therapeutics in 1995 from his apartment and grew it into a public company that brought multiple sclerosis and Parkinson's therapies to market. After Acorda's sale to Merz in 2024, he evaluated roughly two dozen startups before taking the CEO seat at Oryon Cell Therapies in March 2026, a Belmont, Massachusetts company developing autologous neuron replacement therapy for Parkinson's. He is a past Chair of the Biotechnology Innovation Organization (BIO).
biotech · biotechnologyRead →