Osana tried to sell affordable healthcare. Then it discovered the more interesting business was fixing the machinery underneath it - one appointment, API, and anxious patient at a time.
Salvo Health began by asking patients to walk around the healthcare system. Then it discovered the more useful trick: walk through the front door, beside their own doctor.
Welkin Health began by coaching people with diabetes. Then its founders noticed the harder problem: the people delivering care were trapped between spreadsheets, inboxes and software that could not bend.
Sensyne offered hospitals a share of the proceeds from AI research. A cash crisis forced a rescue, a new name and a smaller business - while its pregnancy-diabetes app found a life of its own.
Remote heart devices produce a blizzard of alerts. Octagos raised $43 million to decide which ones deserve a clinician's attention - and to make the rest of the clinic run on time.
Hospitals do not need another dashboard. They need to know who to call before lunch. Lightbeam built a business around that unglamorous handoff from data to action - and says its customers have generated more than $5 billion in gross savings along the way.
The Maryland company learned that FDA clearance was only the opening move. Its more durable play is connecting devices, care teams and everyday decisions - then selling that regulated intelligence through the institutions already paying for chronic care.
The Vancouver medtech spent nearly a decade teaching an implant to report every step. Its more useful lesson came after launch: a stream of numbers is not a product until a care team knows what to do next.
Podimetrics began with an insole, survived an electrical-tape prototype, and found its business in a deceptively simple ritual: stand still for 20 seconds before a wound becomes a crisis.
Current Health began with a wearable, grew into a hospital-at-home operating system, and became a $400 million retail-health wager. Its second act is more disciplined: help hospitals and drugmakers move the hardest care out of the building without making clinicians gamble on safety.
Dr Matt Wilson spent 14-hour shifts in emergency medicine with no time to eat, let alone run a study. So he built a platform that makes the research happen without the clinician lifting a finger - and pharma is paying to plug in.
A family tragedy sent two founders after one of medicine's most subjective rituals. Their bet: short phone tests can make the months between neurology visits visible - if patients, doctors and drug developers trust the measurements.
Wayne Meng went looking for a way to measure his daughter's lung function at home and found a blank shelf. The device he built became the wedge for a broader bet: remote care works better when someone handles the hardware, the data and the human follow-up.
Digital-health companies want to launch lab testing and connect hundreds of devices. Junction does the unphotogenic work in between - integrations, requisitions, logistics, reminders and results - so customers can ship care instead of another six-month infrastructure project.
Lura Health is building a sensor small enough to disappear inside a retainer - and ambitious enough to turn saliva into a continuous stream of health data.
ROMTech has turned the humble rehabilitation pedal into a connected care loop. The bet is simple: recovery works better when therapy is frequent, measurable and close to the couch.
The Dubai-headquartered health platform is trying to turn the daily exhaust of modern life - sleep, steps, stress, blood pressure and more - into an early-warning system people and clinicians can actually use.
True Ventures Group is assembling home care, remote monitoring and virtual medicine under one roof - a practical bet that the hardest part of healthcare is often what happens between appointments.
Dorothea Koh built Bot MD in emerging-market hospitals where the answer a doctor needed was rarely one search away. Today her AI agents field the messages, bookings and follow-ups that used to jam a hospital's phone lines.
Silver Health Plus is building an at-home care operation around a single wager: that the sickest 5% of Medicare patients decline on a schedule you can watch - and interrupt.
Ardent Health is betting that a hospital system can stay local while its technology, purchasing and operating discipline scale nationally. Across six states, the result is a care network stretching from the emergency room to the smartphone.
Teladoc made the video visit ordinary. Now it is attempting the harder trick: turning urgent care, therapy, chronic-condition coaching and hospital technology into one accountable system of care.
Starling Medical is a Houston-based digital health company (Y Combinator W22) building an at-home urine monitoring platform that clips onto a toilet and analyzes urine at every bathroom visit. Using spectroscopy sensors and AI, its UrinDx / StarStream device sends readings to a clinical care team that follows up when something looks off, aiming to catch recurrent UTIs, BPH flare-ups, kidney disease and diabetes complications before they become hospitalizations. The company bills through remote patient monitoring reimbursements, turning routine bathroom trips into a continuous diagnostic stream.
Respiree is a Singapore-founded digital health company (an A*STAR spin-off) building clinically validated AI that pairs FDA-cleared cardio-respiratory wearable sensors with software to track lung and heart biomarkers over time. Its 1Bio platform helps hospitals, health systems and biopharma detect patient deterioration - such as COPD flare-ups and heart failure - days in advance, powering remote patient monitoring, clinical decision support and decentralized clinical trials across Asia-Pacific, Australia and the United States.
Ash (poweredbyash.com) is a New York-based health technology company that gives healthcare organizations a customizable, white-label platform for at-home diagnostic testing. Founded in 2019 as a direct-to-consumer sexual health testing service for the LGBTQ+ community, Ash pivoted to a B2B model that lets health plans, digital health companies and public health agencies launch branded testing programs across 100+ biomarkers in all 50 states. The company handles kit design, a vetted lab network, multilingual patient engagement, logistics and real-time reporting through one API, and has shipped more than 500,000 kits while helping organizations close care gaps and improve HEDIS and Star Ratings measures.
Casana is a Rochester, New York digital-health company that builds the Smart Seat (originally the Heart Seat), a toilet-seat replacement that passively measures vital signs - heart rate, heart rate variability, blood oxygen, respiration rate and blood pressure insights - while a person simply sits, with no wearables, charging or behavior change required. Spun out of research done by founder Nicholas Conn during his PhD at the Rochester Institute of Technology, the company earned FDA 510(k) clearance in 2023 and launched a consumer version of the seat in July 2026.
Datos Health is an AI-driven remote care company that lets hospitals and health systems build and deploy personalized remote patient monitoring programs without code. Its OpenCare platform pairs a drag-and-drop Design Studio with patient-facing CareApps and a robotic-process-automation engine, so care teams can automate everything from cardiac rehab to hospital-at-home and oncology follow-up. Founded in 2015 by Uri Bettesh after a family cardiac emergency, the company is device-agnostic, integrates with existing EHRs, and was named to TIME's list of the World's Top HealthTech Companies of 2025.
Dimer Health is a clinician-led, AI-native transitional care company that manages the high-risk 30 days after a hospital discharge. It pairs licensed clinicians - who it calls Transitionists - with a proprietary clinical AI system, AiME, to monitor patients at home, catch complications early, and reduce avoidable readmissions. Founded in 2023 and based in Florham Park, New Jersey, the company operates a virtual medical practice embedded within health systems and payor networks across eight states.
Healthy.io turns the smartphone camera into a clinical-grade medical device for at-home diagnostics. Founded in Israel in 2013 by Yonatan Adiri, the company uses computer vision, AI and colorimetric analysis to let patients run lab-quality urine tests at home - for kidney disease, urinary tract infections and pregnancy - and gives clinicians AI-powered 3D wound measurement tools. Its flagship Minuteful Kidney test is the first smartphone-powered home test cleared by the FDA to measure the albumin-to-creatinine ratio, and its products are used across US health plans and UK NHS trusts to close gaps in preventative care.
Huma is a London-based digital health technology company that builds a regulated, modular software platform used by hospitals, pharmaceutical companies and governments to run remote patient monitoring, 'hospital at home', companion apps and decentralized clinical trials. Founded in 2011 as Medopad and rebranded to Huma in 2020, it combines predictive algorithms, digital biomarkers and real-world data with a no-code Huma Cloud Platform so partners can launch regulated, disease- and device-agnostic health apps. Its Software as a Medical Device holds EU MDR Class IIb, US FDA Class II and UK MHRA registrations, and its technology has reached thousands of hospitals and tens of millions of patients worldwide.