Virta Health is a digital health company on a mission to reverse type 2 diabetes and obesity in 100 million people. Founded in 2014 by Sami Inkinen, Dr. Stephen Phinney, and Dr. Jeff Volek, Virta pairs a nutrition-first, low-carbohydrate clinical protocol with a Continuous Remote Care platform - a mobile app, dedicated physicians and health coaches, and AI-driven personalization - to lower blood sugar, cut medications, and produce durable weight loss without relying on costly drugs or surgery. Sold to employers and health plans on a value-based, outcomes-guaranteed model, Virta has treated over 100,000 members and surpassed $160M in annualized revenue.
Bloom Science is a San Diego clinical-stage biotech translating the biology of the ketogenic diet into oral live biotherapeutics that act through the gut-immune-brain axis. Built on microbiome research licensed from UCLA and powered by its IrisRx discovery platform, the company is developing BL-001, a once-daily bacterial therapy being studied in obesity and in drug-resistant seizures from Dravet syndrome, with a pipeline reaching toward ALS and neurodegenerative disease.
Peter DiLaura is the CEO and Board Director of Helicore Biopharma, a San Mateo biotech building long-acting antibody-peptide conjugates that go after obesity by neutralizing the GIP hormone in the bloodstream rather than blocking its receptor. With nearly three decades of company-building behind him - CEO roles at Initial Therapeutics and Second Genome, business and strategy chief at Sonoma Biotherapeutics, and time as an Entrepreneur-in-Residence at Third Rock Ventures - he is the operator brought in to turn a $65M Series A and a clinic-ready antibody into medicines that aim for quarterly dosing and better-quality weight loss.
Jahangir Mohammed is a serial entrepreneur and inventor who built Jasper Technologies into the world's largest IoT platform - sold to Cisco for $1.4 billion in 2016 - then turned his attention to metabolic disease. As Founder and CEO of Twin Health, he is using AI-powered whole-body digital twin technology to reverse chronic conditions like Type 2 diabetes, with clinical results published in the New England Journal of Medicine Catalyst showing 71% of participants achieving A1C below 6.5% while eliminating most medications. Twin Health has raised $335 million total and reached a $950 million valuation in 2025.
Signos is a San Francisco Bay Area digital health company pairing a continuous glucose monitor with an AI-driven app to help non-diabetic adults lose weight and improve metabolic health through real-time, personalized feedback on food, sleep, stress and exercise.
Sharam Fouladgar-Mercer is the Co-Founder and CEO of Signos, the company behind the first FDA-cleared over-the-counter glucose monitoring system for weight management. A Princeton computer science graduate and Harvard MBA, he played NCAA Division I ice hockey before building a career spanning VC at Sierra and Shasta Ventures, co-founding PR tech company AirPR (later Onclusive), and ultimately creating Signos in 2018 after his own lifelong struggle with weight and the death of his diabetic grandmother inspired him to ask: why wait until someone is sick to give them metabolic data?
Sam Corcos is a four-time founder and the co-founder and former CEO of Levels Health, a $300M metabolic health company that pairs continuous glucose monitors with a software layer to help people understand how food affects their blood sugar. He co-founded CarDash (Y Combinator S17, acquired 2020), Sightline Maps, and LearnPhoenix before building Levels into a category-defining health company with $67M raised from a16z and a community of 1,400+ member-investors. In 2025, he joined the Department of Government Efficiency (DOGE) and was appointed U.S. Treasury Chief Information Officer. He is also known for extreme minimalism (one pair of pants, one backpack), tracking time in 15-minute increments, and hosting 100+ intellectual salon dinners in New York and San Francisco.