athenahealth doesn't see patients. It runs the billing, charts, and reminders for the clinicians who do - and it's betting the whole network on AI.
Quest Diagnostics is easy to mistake for a chain of blood-draw centers. Its real product is a national system that moves specimens, data and decisions through American healthcare at unusual scale.
It started as a chain of psychiatric hospitals in Georgia. Fifty-plus years later, Magellan Health decides how millions of Americans get their mental health care approved - and after a $2.2 billion round trip through Centene, it is about to be on its own again.
The company betting that the most expensive corner of American medicine - cancer, cardiology, and back surgery - can be run better when the people paying for care and the doctors delivering it are finally pulling in the same direction.
Aktivo Labs is a Singapore-based digital health-science company that turns everyday smartphone and wearable data into a proprietary digital biomarker, the Aktivo Score, a 1-99 measure of an individual's risk for chronic disease. It sells its platform to life and health insurers, reinsurers and employers, helping them run evidence-based wellness programs and understand population health risk. Founded in 2017, the company raised a US$10M Series A led by Mitsui & Co. in 2022 and operates across Asia-Pacific with expansion into the US, Europe and Japan.
Senan Ebrahim is the founder and CEO of Delfina, a San Francisco digital health company using AI and data science to improve pregnancy care and close gaps in maternal health. A physician-scientist with an MD and a PhD in computational neuroscience from Harvard, he founded Delfina after witnessing a preventable stillbirth during medical training. He earlier founded Hikma Health, a nonprofit building free health-data tools for refugee and low-income patients. Delfina raised a $17M Series A in early 2025 led by U.S. Venture Partners.
Mesh Bio is a Singapore-based health deep-tech company that uses digital twin technology and predictive analytics to help clinicians detect and manage chronic diseases earlier. Its DARA platform automates health-screening report generation and risk stratification, while HealthVector Diabetes - approved as a Software as a Medical Device by Singapore's Health Sciences Authority - forecasts diabetes complications years before onset. Founded in 2018 by Andrew Wu and Arsen Batagov, the company serves more than 40 healthcare groups across Asia and has assessed over 300,000 patients.
Ash (poweredbyash.com) is a New York-based health technology company that gives healthcare organizations a customizable, white-label platform for at-home diagnostic testing. Founded in 2019 as a direct-to-consumer sexual health testing service for the LGBTQ+ community, Ash pivoted to a B2B model that lets health plans, digital health companies and public health agencies launch branded testing programs across 100+ biomarkers in all 50 states. The company handles kit design, a vetted lab network, multilingual patient engagement, logistics and real-time reporting through one API, and has shipped more than 500,000 kits while helping organizations close care gaps and improve HEDIS and Star Ratings measures.
Blooming Health is a New York-based social care technology company using AI to automate access to social services for older adults and vulnerable populations. Its AI-assisted, multilingual platform engages people across text, voice, and email to detect needs, screen for benefits, and connect them to services like meals, transportation, housing assistance, and Medicaid or SNAP recertification. Sold to Area Agencies on Aging, government agencies, community-based organizations, and healthcare providers, the platform has connected over 1.5 million people across roughly two dozen states and raised $32.5 million to date, including a $26 million Series A led by Insight Partners in April 2025.
Datos Health is an AI-driven remote care company that lets hospitals and health systems build and deploy personalized remote patient monitoring programs without code. Its OpenCare platform pairs a drag-and-drop Design Studio with patient-facing CareApps and a robotic-process-automation engine, so care teams can automate everything from cardiac rehab to hospital-at-home and oncology follow-up. Founded in 2015 by Uri Bettesh after a family cardiac emergency, the company is device-agnostic, integrates with existing EHRs, and was named to TIME's list of the World's Top HealthTech Companies of 2025.
Healthcare Highways is a Frisco, Texas-based health plan and provider network company that builds and operates curated, high-performance medical provider networks. Founded in 2010, it helps self-funded and level-funded employers, health systems, brokers, and third-party administrators lower healthcare costs and improve access by aligning the interests of providers, employers, and members - offering an alternative to the large national insurance carriers.
Huma is a London-based digital health technology company that builds a regulated, modular software platform used by hospitals, pharmaceutical companies and governments to run remote patient monitoring, 'hospital at home', companion apps and decentralized clinical trials. Founded in 2011 as Medopad and rebranded to Huma in 2020, it combines predictive algorithms, digital biomarkers and real-world data with a no-code Huma Cloud Platform so partners can launch regulated, disease- and device-agnostic health apps. Its Software as a Medical Device holds EU MDR Class IIb, US FDA Class II and UK MHRA registrations, and its technology has reached thousands of hospitals and tens of millions of patients worldwide.
Marigold Health is a Boston-based digital behavioral health company that combines certified peer recovery coaches with a 24/7 anonymous, text-based support community. Natural language processing scans member conversations to flag emerging needs and route human support where it matters most, helping people with mental health and substance use conditions stay engaged in recovery. Marigold contracts primarily with Medicaid and dual-eligible health plans under value-based arrangements, and became the largest provider of peer recovery supports in Delaware.
MDClone is a healthcare data company that lets clinicians, researchers, and analysts explore patient data without touching real patient records. Its ADAMS platform ingests structured and unstructured health-system data into a longitudinal database, then generates statistically faithful synthetic data that carries no risk to patient privacy. That combination turns months-long, IRB-heavy data requests into self-service exploration, letting front-line staff ask their own questions, run analyses, and share results across organizations. Founded in Israel in 2016 and used across the U.S., Canada, and 100% of the Israeli healthcare market, MDClone has raised roughly $112M to expand data-driven discovery in health systems, government, payers, and life sciences.
Percipio Health is a Plano, Texas company that turns an ordinary smartphone into a whole-person health monitor, using AI to read vision- and voice-based biomarkers - vitals, medication adherence, brain health and social determinants - without any dedicated medical devices. Founded by digital-health veterans Eric Rock and David Lucas, the team behind Vivify Health and MEDHOST, the platform helps health plans and providers catch rising-risk and high-risk patients earlier and manage large populations at lower cost. It launched publicly in January 2025 alongside a $20M Series A led by UPMC Enterprises, WAVE Ventures and Labcorp.
Vytalize Health is a value-based care enabler and Accountable Care Organization (ACO) that helps independent primary care physicians care for Medicare patients while lowering the total cost of care. Founded in 2014 and headquartered in Hoboken, New Jersey, it pairs a physician-built clinical data platform (Vytal Insights) with a wraparound clinical team and virtual clinic (Vytal Care) so small practices can succeed in Medicare's advanced value-based programs like ACO REACH and MSSP. The company serves hundreds of thousands of Medicare beneficiaries across dozens of states and was named the No. 1 fastest-growing private company in America by Inc. in 2024.
Eric Rock is the co-founder and CEO of Percipio Health, a Dallas-based company using AI and an ordinary smartphone - no medical devices - to collect whole-person health signals for scalable population health monitoring. A serial healthcare and technology entrepreneur, Rock previously founded ProHost (acquired by OpenTable), MEDHOST (a pioneering touchscreen emergency-department EMR), and Vivify Health, which grew into one of the largest remote patient monitoring platforms before Optum acquired it. Percipio launched in 2025 with $20M in Series A funding and a mission to bring proactive, low-cost care to entire populations.
Cozeva is a cloud-based, real-time data platform built by Applied Research Works that helps health plans, physician organizations, and their partners move from fee-for-service to value-based care. It unifies quality measurement (HEDIS, Medicare Stars, P4P), risk adjustment (HCC coding and recapture), and population health analytics in a single, EHR-interoperable system that lets clinicians act on care gaps at the point of care. Founded in 2012 and based in San Ramon, California, Cozeva serves 25M+ lives and 97,000+ providers, holds NCQA and HITRUST certifications, and earned Best in KLAS recognition in 2025 and 2026. In October 2025 it merged with Vatica Health to combine top-ranked quality and risk-adjustment platforms.
Delfina is a San Francisco-based maternal health company that pairs an AI-powered clinical platform with a consumer pregnancy app to make prenatal care proactive rather than reactive. Its predictive models flag rising risk - preterm birth, hypertensive disorders, gestational diabetes - while patients track vitals from home and connect around the clock with bilingual virtual doulas, dietitians, and mental health support. Founded in 2021 by physician-scientist Dr. Senan Ebrahim and his co-founders, Delfina sells to health plans, providers, and employers, and has raised roughly $22M to date, including a $17M Series A in January 2025.
Simple HealthKit is a Milpitas, California-based digital health company building end-to-end healthcare infrastructure that unifies at-home and in-clinic diagnostics, a CLIA-certified lab, telehealth, and follow-up care into a single platform. Founded in 2018 by biochemist Sheena Menezes, the company targets health equity by making testing for sexual health, respiratory illness (COVID/flu/RSV), and chronic conditions like diabetes accessible and affordable for underserved populations, selling primarily to health plans, retailers, pharmacies, employers, schools, and public health organizations.
Vynca is a healthcare company focused on serious illness and end-of-life care. Founded in 2013 out of Stanford Biodesign, it began as advance care planning software that put patients' end-of-life wishes into the electronic health record, then expanded into hands-on clinical services. Today it combines home-based and virtual palliative care, care navigation, and enhanced care management with technology, partnering with health plans and providers to keep seriously ill patients comfortable, out of the hospital, and cared for on their own terms.
Acentra Health is a McLean, Virginia healthcare technology and clinical services company formed in 2023 from the merger of CNSI and Kepro. It builds Medicaid and Medicare systems, care management platforms, and quality-oversight services for state and federal government health programs, combining public-sector software with clinical staff who review authorizations, assessments, and appeals. Backed by The Carlyle Group, it employs roughly 3,300-3,400 people across the U.S. and India.
Chronica is a San Diego digital-health company that runs remote patient monitoring (RPM) and chronic care management (CCM) as a managed service. Built on parent company Hifinite Health's hiCare platform, Chronica pairs a cloud-based, HIPAA-compliant software stack with the parts most clinics don't want to build themselves: the connected devices, the in-house clinicians, the call center, and the billing paperwork tied to CMS reimbursement codes. Providers - from outpatient practices to hospitals, ACOs, and home-health agencies - get to extend care beyond the exam room without upfront costs, long contracts, or patient minimums.
GenieMD is a San Ramon, California virtual care company that sells a single, white-label platform folding together telehealth, remote patient monitoring, remote therapeutic monitoring and chronic care management - plus built-in e-prescriptions, lab integration and CPT billing reports. Founded in 2010 by Stanford-trained engineer Soheil Saadat, it sells to hospitals, health systems, group practices, insurers, ACOs and employers, and in 2026 launched HelloGenie, a free AI doctor that hands patients off to real board-certified physicians when actual care is needed. Frost & Sullivan named it 2024 Company of the Year for virtual chronic disease management.
Karoo Health is an Albuquerque, New Mexico company building tech-enabled, value-based cardiovascular care. It pairs wraparound care teams - nurses, dietitians, pharmacists, health coaches and advanced-practice providers - with Kohere.ai, a proprietary platform that aggregates patient data, flags risk and coordinates communication. The model helps cardiology networks, health systems and health plans move from fee-for-service to value-based arrangements, aiming to improve heart-patient outcomes while lowering the cost of care.
Radial (Radial Analytics, Inc.) is a Concord, Massachusetts healthcare technology company that builds AI-driven decision support software for value-based care. Its flagship platform, Smart Placement, uses machine learning and natural language processing to help hospitals, health plans, and accountable care organizations decide - in real time - which patients can safely recover at home instead of in a skilled nursing facility after a hospital stay. Founded in 2014 by former Locately co-founders Thaddeus Fulford-Jones and Eric Weiss alongside physician Anant Vasudevan, Radial applies 'nudge theory' at clinical crossroads moments to lower costs and improve outcomes without overriding clinician judgment.
WovenX Health (formerly Telebelly Health) is a Chicago-based digital health company that weaves on-demand virtual specialty care into existing gastroenterology, hepatology, and urology practices. It pairs specialty-trained Advanced Practice Providers with real-time MD supervision and an AI-guided software platform to shrink wait times, speed patients to procedures like colonoscopy, and expand capacity for practices and health systems without adding staff or brick-and-mortar.
MiSalud Health is a bilingual, AI-powered hybrid healthcare platform built for the Spanish-speaking workforce in the U.S. and Mexico. It pairs same-day virtual consultations in Spanish and English with on-site biometric screenings, mental health support, chronic condition management and nutrition coaching, delivered through employer partnerships that reach over 100,000 members. The company combines culturally tailored care with measurable cost savings, reporting 80% enrollment, 97% satisfaction and 3.5x ROI for its clients.
Trayt Health is a Menlo Park, California company building a patient-centric, clinician-directed software platform that coordinates behavioral and mental health care across primary care, schools, and specialty clinicians. Its platform powers statewide psychiatry access programs and managed care organizations by tracking 750+ symptoms and factors, streamlining consultations and referrals, and turning granular patient data into population-level insights. As of 2026 it supports roughly 20 statewide behavioral health programs across eight U.S. states.
Linda Finkel is a healthcare technology executive who runs OutcomesAI, a Boston-based company pairing AI voice agents with licensed nurses to expand nursing capacity through its Glia engine. Before OutcomesAI she spent over a decade building AVIA into the country's leading digital transformation partner for health systems, first as president from 2014 and then as CEO from 2020. A Stanford BA and Harvard MBA, she earlier ran large international services companies including Bowne Business Solutions and Donnelley Business Services, and pivoted to healthcare after watching her father's 91-day ICU stay reveal both the heroism and the gaps in modern care. She has been named one of the Top 50 Women Leaders in Healthcare.