interoperability
(30)
The Patient Portal Was Never the Point
Osana tried to sell affordable healthcare. Then it discovered the more interesting business was fixing the machinery underneath it - one appointment, API, and anxious patient at a time.
Nervecentre wants the whole hospital on the same page
A bedside software specialist is taking on the hospital-wide patient record. Its NHS contracts reveal the appeal of shared information - and the hard work of getting everyone to use it.
R3 built blockchain for banks. Now it wants to open the gates.
Corda brought shared ledgers into the financial back office. R3’s next wager is that the assets inside those private networks can find a bigger market on Solana.
TPP wants your medical record to stop starting over
The company behind SystmOne has built a business around a simple promise: one patient, one record. Its most revealing results come from fixing the small administrative failures that make healthcare feel so disjointed.
Parity built the machinery. Now comes the human part.
The engineers behind Polkadot spent a decade making blockchains work together. Their next test is whether people can use the result without needing a blockchain education.
Qualifacts Built a Behavioral-Health EHR Empire. The Bet Is That Three Platforms Beat One.
Qualifacts assembled three EHRs for three different kinds of behavioral-health provider. Now it is using AI, interoperability, and targeted acquisitions to turn that portfolio into something closer to an operating system for care.
Lightbeam Found Billions in Healthcare’s Messy Middle - Then Turned a Customer Into Its Operator
Hospitals do not need another dashboard. They need to know who to call before lunch. Lightbeam built a business around that unglamorous handoff from data to action - and says its customers have generated more than $5 billion in gross savings along the way.
The BlueJeans Playbook: Build the Bridge, Sell for Under $500 Million, and Know When Bundles Win
BlueJeans made incompatible cameras talk, grew to 25 million users, and sold to Verizon at the precise moment video became oxygen. Its shutdown four years later is a useful warning: a brilliant bridge can still lose when the platforms on both sides become the destination.
The Standards Group That Made 4,500 Smart-Home Gadgets Actually Talk to Each Other
It doesn't sell a single gadget. It sells a promise - that the smart lock, the motion sensor and the hub in your hallway will all speak the same language, no matter whose name is on the box.
The Back Office Behind One in Five American Doctor Visits
athenahealth doesn't see patients. It runs the billing, charts, and reminders for the clinicians who do - and it's betting the whole network on AI.
Surtr Defense Systems
Surtr Defense Systems builds ParallaxOS, a hardware-agnostic operating system for drone defense. It ingests data from any radar, RF detector, camera, or acoustic array, fuses it into a single common operating picture, applies AI threat classification, and passes human-authorized engagement recommendations to any effector. Founded in 2026 by two former Shield AI and Anduril autonomy engineers, the company is a Y Combinator Spring 2026 (P26) startup that raised roughly $4.8M in seed funding and field-tested its system with Ukraine's Brave1 defense cluster.
BetterHealthcare
BetterHealthcare is a New York-based healthcare technology company that modernizes patient access through its BetterAccess platform, a HIPAA-compliant SaaS product for online self-scheduling, telehealth booking, automated reminders and bi-directional integration with practice management and EHR systems. Founded in 2016 as BetterPT - a booking app for physical therapy - the company broadened into a full patient-access platform used across the continuum of care and was acquired by HealthBus (TRCM Fund) in January 2025.
DeFi Devs
DeFi Devs is a Miami-based blockchain and AI development company that serves as the lead community developer of the Accumulate Protocol, an identity-based, delegated-proof-of-stake blockchain built for decentralized finance, digital identity, and enterprise tokenization. Founded in 2021 as a subsidiary of Inveniam Capital Partners and led by Factom founder Paul Snow, the firm builds infrastructure for cross-chain atomic transactions, human-readable addresses, and hierarchical key management, positioning Accumulate as an 'Internet of Blockchains' that bridges regulated real-world assets onto decentralized rails.
IgniteData
IgniteData is a healthtech company automating the transfer of clinical trial data between hospital electronic health records (EHRs) and sponsors' electronic data capture (EDC) systems. Its flagship platform, Archer, is a cloud-based, system-agnostic 'Virtual Research Assistant' that uses HL7 FHIR and SMART on FHIR APIs to move clinically validated data securely and automatically, cutting manual transcription, reducing source data verification, and helping treatments reach patients faster. Founded in the UK and now operating on both sides of the Atlantic, IgniteData works with pharmaceutical sponsors like AstraZeneca and research hospitals including UCLH, Cambridge University Hospitals, and Memorial Sloan Kettering Cancer Center.
Noble
Noble is a purpose-built blockchain for native asset issuance, focused on stablecoins and tokenized real-world assets. Built on the Cosmos SDK and connected through IBC, it is the canonical home of native USDC in the Cosmos ecosystem and the issuer of the yield-bearing Noble Dollar (USDN). Founded in 2022 by Jelena Djuric, Stefan Coolican and John Letey after the collapse of Terra's UST, Noble gives issuers such as Circle, Ondo Finance, Hashnote and Monerium a neutral, compliant rail to mint dollars and distribute them across dozens of connected chains - with no gas token required and fees paid in USDC.
Predoc
Predoc is a New York-based, clinician-founded startup building an AI-native platform for health information management. It automates the retrieval, cleaning, and structuring of patient medical records - pulling data from digital sources, faxes, and direct provider requests - and turns fragmented, unstructured documents into normalized, actionable data that plugs into existing clinical and research systems. Founded in 2022, the company raised $30M (Series A led by Base10 Partners) and serves oncology groups, research networks, and virtual care providers.
Snaptrude
Snaptrude is a cloud-based, AI-native design platform for architecture, engineering and construction (AEC) teams. It lets architects move from a brief to a BIM-ready model inside one connected, browser-based workspace - handling site analysis, space programming, massing, BIM modeling and presentation while staying interoperable with legacy tools like Revit, Rhino and Archicad. Founded in 2017 by Altaf Ganihar and backed by Foundamental and Accel, Snaptrude positions itself as a modern, collaborative alternative to design software largely built in the late 1990s.
Vim
Vim is a healthcare technology company that builds a middleware and developer platform connecting data to clinical workflow at healthcare's 'last mile' - the point of care. Its EHR-agnostic Vim Connect layer sits on top of popular electronic health records, pulling in insights and applications from payers, health plans, and digital-health innovators and surfacing them directly inside a provider's existing workflow. By automating tasks such as care gap closure, diagnosis capture, prior authorization, referral management, and chart retrieval, Vim helps payers and providers align on value-based care while reducing administrative burden for clinicians.
RISA Labs
RISA Labs is a Palo Alto healthtech company building an AI operating system for oncology. Its platform, BOSS (Business Operating System as a Service), decomposes the paperwork-heavy work of cancer care - prior authorization, benefits verification, eligibility checks, denial management - into micro-tasks handled by a network of AI agents, digital twins, and reinforcement learners that plug into EHRs and payer portals. Founded in 2024 by IIT Kanpur alumni Kshitij Jaggi and Kumar Shivang, RISA aims to cut the days-long administrative delays that keep cancer patients waiting for treatment.
Medplum
Medplum is an open-source, API-first, FHIR-native healthcare developer platform - a 'Firebase for Healthcare' that gives engineers a HIPAA- and SOC2-ready backend so they can ship custom EHRs, patient portals, and clinical workflows without rebuilding the plumbing.
Succinct
Succinct is a San Francisco cryptography company building SP1, an open-source zero-knowledge virtual machine that lets developers prove the correct execution of any Rust program, and the Succinct Prover Network - a decentralized marketplace where independent provers compete to generate ZK proofs for rollups, bridges and onchain applications.
NexHealth
NexHealth is a San Francisco-based health technology company building the patient experience platform for medical and dental practices. Its software gives doctors EHR-integrated online scheduling, patient messaging, digital paperwork, recalls, reviews and payments, while its Universal API and proprietary Synchronizer let developers read and write data across 20+ practice management systems in real time. Founded in 2017 by Alamin Uddin and Waleed Asif, NexHealth reached unicorn status in 2022 with a $125M Series C at a $1B valuation and serves more than 10,000 practices.
HealthEx
HealthEx is a San Francisco healthcare technology company building a patient consent and preference platform that lets individuals authenticate, access, and share their comprehensive health records in real time - while giving health systems a way to enforce granular consent across the care journey. Founded in 2024 by physician Priyanka Agarwal and engineer Anand Raghavan, it raised $14M led by General Catalyst and operates under the federal TEFCA framework, connecting patients to most U.S. care providers through partners like Epic, athenahealth, CLEAR, and CommonWell.
HERE
HERE is the enterprise browser company formerly known as OpenFin. Built on Google Chromium, its software turns the workday browser into a unified workspace - stitching web apps, internal tools and data together so employees stop paying the 'toggle tax' of jumping between disconnected applications. After 14 years winning over the world's largest banks with its desktop interoperability platform, OpenFin relaunched as HERE in June 2024 to take the same technology beyond finance into contact centers, healthcare, government and any enterprise drowning in browser tabs.
Vocera Communications, now part of Stryker
Vocera Communications builds the hands-free, voice-controlled communication tools that hospitals use to connect care teams in real time. Founded in 2000 and inspired by the Star Trek communicator badge, Vocera's wearable Badge and Smartbadge, plus its Vina app and Engage intelligent-workflow platform, let clinicians reach a colleague by name, role, or group with a single voice command. Used in roughly 2,300 facilities worldwide and integrated with more than 150 clinical and operational systems, Vocera went public in 2012 (NYSE: VCRA) and was acquired by medical-technology giant Stryker in February 2022 for about $3.09 billion, where it now anchors Stryker's digital care coordination portfolio.
WellStack
WellStack is a Madison, Wisconsin healthcare data platform that unifies fragmented clinical, financial, and operational data into a single governed source of truth. Built on a cloud-native Unified Data Model and a Snowflake foundation, it gives providers, payers, and data collaboratives out-of-the-box Patient/Member 360 views, modular Decision Hubs, and AI/ML-ready analytics - so healthcare organizations can predict, prevent, and personalize care without the years-long data-engineering slog.
TBCASoft
TBCASoft is a Silicon Valley blockchain company building a consortium-based distributed ledger that lets telecom carriers, mobile payment apps and banks interoperate across borders. Its HIVEX payment network lets travelers pay with their home QR-code wallet abroad without merchants changing POS systems, while the CBSG Consortium and CCIS identity framework extend the same trust rails to digital identity and authentication. Founded in 2016 by Ling Wu, it is backed by SoftBank and Naver and connects payment apps reaching tens of millions of users across Asia.
YEBO
YEBO is a Los Angeles Web3 company building no-code tools that let brands and creators design 3D virtual stores and launch interoperable NFT rewards and loyalty programs. Its stated mission is to bring people into Web3 by letting them create their own digital assets - buildings, stores, products - that can move freely from one Web3 environment to another. Founded in 2013 and later repositioned around blockchain rewards, YEBO is led by serial entrepreneur and Bitvore co-founder David Mandel.
KoreLock
KoreLock is a Denver-based IoT smart lock technology company that gives lock manufacturers and access control providers a turnkey, patented platform - embedded firmware, custom PCBAs, mobile and web apps, and cloud APIs - to turn ordinary offline locks into Wi-Fi and Bluetooth connected devices. Rather than competing with lock makers or software companies, KoreLock positions itself as the interoperability bridge between hardware and access control software, with technology already embedded in tens of thousands of devices across 65+ countries.
Peregrine
Peregrine is a San Francisco-based data intelligence platform that unifies fragmented public safety data - from body-worn cameras and CAD records to RMS and ALPR feeds - into a single, searchable system for law enforcement, fire-rescue, EMS, and emergency management agencies. Founded in 2018 by ex-Palantir operators, it now serves jurisdictions covering more than 80 million Americans and reached a $2.5B valuation after a $190M Series C led by Sequoia in March 2025.