OpenCall.ai is a San Francisco AI startup (Y Combinator W24) that builds AI voice agents to answer, route, and resolve business phone calls. Trained on thousands of real-world workflows, its agents book appointments, verify insurance, and update records, integrating with existing software and going live in under an hour. The company targets service businesses - especially healthcare practices - promising to capture missed-call revenue while cutting call-handling costs by 50-80%.
Twine is an AI revenue engine for small service businesses. When a business misses a call, Twine instantly texts the caller back, figures out what they need, books the job on the calendar, and follows up - so plumbers, HVAC techs, salons and pest-control operators stop losing work to whoever picked up first. Founded in 2023 and backed by Y Combinator (S23), Twine unifies calls, texts, web forms and chat into one AI-run inbox.
Colavo Ground is a Seoul-founded software company behind ColavoSalon, a free mobile-first CRM and booking platform for independent beauty professionals and salons. It bundles online booking, an appointment calendar, automated multi-channel reminders, loyalty and package tools, staff commissions and sales analytics into one app, aiming to cut no-shows and improve client retention. Colavo says it is used by well over 100,000 beauty pros across dozens of countries, and has raised roughly $3.77M, with a Series A round in 2021.
Confido Health builds AI voice and messaging agents that answer patient phone calls for healthcare providers around the clock. The agents pick up on the first ring, authenticate callers, check insurance eligibility, and resolve routine requests end-to-end - scheduling, refills, referrals, payments, intake and post-visit follow-up - writing every interaction back into the practice's EHR or practice-management system. Founded in 2023 and based in New York, the company raised a $10M Series A in September 2025 and provides access to more than 1 million patients.
EliseAI is a New York-based artificial intelligence company that builds conversational and agentic AI to automate the routine, high-volume communication work of two administratively heavy industries: rental housing and healthcare. Its assistants answer calls, emails, texts and chats around the clock - scheduling tours, handling maintenance and renewals, collecting rent, and booking patient appointments - so property and clinic teams can focus on people rather than paperwork. Founded in 2017 as MeetElise, the company crossed $100M in annual recurring revenue, serves roughly 70% of the 50 largest U.S. rental housing operators, and reached a $2.2 billion valuation with its 2025 Series E led by Andreessen Horowitz.
Mia Labs is an Austin-based AI company building Mia, a voice-first conversational platform for automotive dealerships. Marketed as an 'AI super employee,' Mia answers inbound and outbound calls 24/7 across a dealership's sales, service, reception, and parts departments, syncing with dealer management systems, CRMs, and scheduling tools to capture leads, book appointments, and handle routine customer conversations. As of early 2026 the platform served more than 350 franchise dealerships and had raised a $20M Series A, bringing total funding to roughly $29M.
Arini is a San Francisco-based AI company that builds a voice and text receptionist for dental practices. Its AI agent answers patient calls 24/7, books and reschedules appointments directly into practice management software, and handles insurance and billing questions - aiming to recover the revenue clinics lose when front desks miss roughly a third of inbound calls. Founded in 2024 by Abdulrahman Jamjoom and Rami Rustom, both former engineers on Meta's Threads team, the company went through Y Combinator's Winter 2024 batch and now handles over 15,000 patient calls a day for dental groups and DSOs across the US and Canada.
Clarion builds an AI communication layer for healthcare that answers the phones, texts, and web chats clinics can't keep up with. Its voice, SMS, and web agents handle scheduling, prescription refills, billing questions, referral intake, and after-hours follow-up, integrating with 80-plus EHR systems including Epic and Cerner. Founded in 2024 by a Stanford/Harvard-trained physician and an ex-Amazon Alexa voice-AI engineer, the New York company is a Y Combinator W24 startup backed by Accel and Airtable Ventures, and says it serves tens of thousands of patients a month across virtual-care companies, health systems, and a large health insurer.
Mascotte is a Miami-based, tech-enabled operations company that gives veterinary clinics dedicated remote staff - CSRs, receptionists and vet techs - trained to each practice's own workflows and assigned exclusively to it. Branded internally as 'Mascotteers', these full-time team members handle phones, scheduling, prescription coordination, lab follow-ups and client communication inside the clinic's existing systems, promising up to 50% cost savings versus a local hire while reducing staff burnout. Founded in 2023 by former CarHopper CEO Bora Hamamcioglu and backed by a $1.2M pre-seed led by Nuwa Capital, Mascotte positions itself as the virtual front desk and back office for modern, high-growth veterinary practices.
Reviva is an AI-native practice management platform and EHR built for cash-pay health and wellness practices - medical spas, longevity clinics, IV therapy bars, and functional medicine providers. It folds scheduling, charting, payments, memberships, CRM, and marketing automation into a single system you can operate by telling it what to do. Founded in 2024 by Valerie Huynh and Jane Jeong, the daughters of immigrant small-business owners, Reviva aims to give solo and small wellness practices the kind of software leverage that used to belong only to big hospital systems.
Velostics is a Houston-based logistics SaaS company building an AI-enabled platform that unifies dock and yard operations. Its software automates 3-way appointment scheduling between shippers, carriers and consignees, digitizes gate check-in, and uses AI voice agents to book, confirm and reschedule loads without manual phone tag. Founded in 2019 by ChaiOne CEO Gaurav Khandelwal, the company helps manufacturers, distributors and 3PLs cut detention, dwell time and freight costs by closing the gap between transportation and distribution.
Vagaro is a Pleasanton, California SaaS company that runs the back office for salons, spas, fitness studios, and wellness businesses. From a single dashboard, owners book appointments, take payments, manage staff and inventory, run marketing, and get discovered on a consumer marketplace and app. Founded in 2009 by Fred Helou, it now serves more than 83,000 businesses across the US, Canada, UK, and Australia, reached a $1 billion valuation in 2021, and bundles scheduling, point-of-sale hardware, embedded payments, and AI tools into one subscription.
Assort Health builds specialty-specific voice AI agents that answer patient phone calls for medical practices and health systems, resolving them rather than routing them. Trained on more than 150 million patient interactions and integrated directly into EHR and practice-management systems, its agentic platform schedules appointments, triages, verifies insurance, handles refills and follows up with patients across 20+ specialties. Founded in 2023 by Jeff Liu and Jon Wang, the San Francisco company raised a $76M Series B in 2025, bringing total funding to $102M.
Engageware is a Tewksbury, Massachusetts company that builds AI-powered customer engagement software for regulated industries, especially banks and credit unions. Born from appointment-scheduling pioneer TimeTrade (founded 1999) and reshaped through the acquisitions of SilverCloud and Argentina's conversational-AI firm Aivo, the platform combines AI agents, intelligent appointment scheduling, and knowledge management to automate routine inquiries and hand customers to a human when it counts. It is trusted by more than 600 organizations across 20+ countries and has orchestrated roughly three billion customer interactions.
GlossGenius is a New York-based vertical SaaS and fintech platform that gives independent beauty and wellness professionals - hair stylists, nail techs, estheticians, spas and medspas - one app to run the whole business. It combines online booking, a built-in card-processing POS, client CRM, marketing automation, payroll, inventory and AI agents, replacing the patchwork of spreadsheets, paper books and generic tools that solo operators and small salons relied on. Founded in 2016 by Danielle Cohen-Shohet, it crossed roughly $100M in revenue, serves tens of thousands of businesses, and reached unicorn status with a reported $1.12B valuation after its January 2026 Series D.
Zocdoc is a New York-based healthcare marketplace that lets patients find in-network doctors and dentists, read verified reviews, and book in-person or telehealth appointments in real time - free for patients, paid for by providers who advertise their open slots. Founded in 2007 after a co-founder's burst eardrum exposed how hard it is to get a timely appointment, Zocdoc now serves millions of patients monthly across all 50 states, hundreds of specialties, and thousands of insurance plans, and in 2025 added Zo, an AI voice agent that answers scheduling calls 24/7.
Luma Health is a San Mateo healthcare technology company building an Operational AI platform that unifies patient access, scheduling, intake, communication, and payments. Its Spark multi-model AI powers products like Navigator (voice concierge) and Fax Transform, used by more than 650 health systems and clinics serving over 55 million patients across 200,000+ providers.
Numa is the leading AI platform for automotive dealerships, powering customer operations across 1,300+ rooftops in the U.S. and Canada. Founded by the team behind Location Labs (acquired by AVG for $220M), Numa's AI agents handle calls, texts, appointments, and customer satisfaction monitoring - reducing response times from 24 hours to 20 minutes and driving measurable increases in dealership profitability and CSI scores.
Melody McCloskey is the founder and CEO of StyleSeat, the largest online marketplace for beauty, grooming, and wellness services, connecting over 350,000 independent beauty professionals with 10 million+ consumers across the United States. She co-founded StyleSeat in 2011 alongside Dan Levine, bootstrapped the company for 18 months before raising $40.7 million in venture funding, and has helped power over 200 million appointments while generating $12+ billion in total revenue for small businesses. A San Francisco native who studied French and International Relations at UC Davis, McCloskey built StyleSeat out of her own frustration with booking beauty appointments, turning a personal pain point into a platform that fundamentally reshaped how independent beauty professionals run their businesses. She is also an angel investor and Cleo Capital scout, focused on backing female-led startups at the pre-seed through Series A stages.
Monik Pamecha is the Co-Founder and CEO of Toma, an AI voice platform built for automotive dealerships. A programmer since age 11-12, he published ML research in 2016, built AI at Uber, Turing.com, and Braze, and co-founded Skindex (a skincare AI startup that was acquired) before landing in the car business - almost by accident. Toma, backed by Y Combinator and Andreessen Horowitz with a $17M Series A, automates inbound calls, appointment scheduling, and customer follow-ups for 100+ U.S. dealerships, handling over 1 million call minutes and approaching eight-figure ARR in under two years.