ai-in-healthcare
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The Fund Betting That the Poorest ZIP Codes Are the Best Returns
Andy Slavitt ran Medicare. Now he runs a $1.4 billion fund arguing that the patients Wall Street ignores are where the money is - and the math, so far, agrees.
Redesign Health Turned Starting a Healthcare Company Into a Repeatable Process
The New York studio has launched more than 60 healthcare companies since 2018 by treating the messy work of starting one - ideas, diligence, hiring, capital - as a system you can run again and again.
Omniscient Neurotechnology (o8t)
Omniscient Neurotechnology (o8t) is a Sydney-based brain-mapping company that uses AI and machine learning to turn ordinary MRI scans into detailed maps of the brain's electrical networks, or connectomes. Its flagship FDA-cleared platform, Quicktome, gives neurosurgeons a patient-specific view of the pathways responsible for speech, movement and cognition before they operate, while its research platform, Infinitome, helps scientists study how diseases like Alzheimer's, epilepsy and schizophrenia disrupt brain connectivity. Founded in 2019 and led by CEO Stephen Scheeler, the company has raised roughly US$124 million to date and is expanding connectomics into stroke, movement disorders and brain-computer interfaces.
BostonGene
BostonGene is a Waltham, Massachusetts biotechnology company that applies AI-driven multiomics to cancer. Its Tumor Portrait platform integrates DNA and RNA sequencing with immune and tumor-microenvironment analysis into a single test, producing molecular profiles that help oncologists select therapies and help pharmaceutical partners design trials, identify biomarkers, and accelerate drug development. Founded in 2015 and led by CEO Andrew Feinberg, the company reached unicorn status in 2022.
Castor
Castor is a health-technology company that builds a cloud-based eClinical platform for running clinical trials - from electronic data capture (EDC) and eConsent to eCOA/ePRO and real-world evidence. Founded in 2012 in Amsterdam by physician-researcher Dr. Derk Arts, Castor set out to replace clunky, expensive trial software with a self-service, researcher-friendly system. Today it supports more than 15,000 studies across 90+ countries and is used by leading CROs and biopharma companies, while pushing decentralized trials and practical AI (Castor Catalyst, built with Google Cloud) into mainstream research.
Datos Health
Datos Health is an AI-driven remote care company that lets hospitals and health systems build and deploy personalized remote patient monitoring programs without code. Its OpenCare platform pairs a drag-and-drop Design Studio with patient-facing CareApps and a robotic-process-automation engine, so care teams can automate everything from cardiac rehab to hospital-at-home and oncology follow-up. Founded in 2015 by Uri Bettesh after a family cardiac emergency, the company is device-agnostic, integrates with existing EHRs, and was named to TIME's list of the World's Top HealthTech Companies of 2025.
H1
H1 is a New York-based healthcare data and technology company that maps the world's healthcare professionals, clinical trials and provider networks into a single platform. Founded in 2017 by Ariel Katz and Ian Sax, H1 aggregates billions of data points - peer-reviewed publications, clinical trial records, medical claims and provider directories - so pharmaceutical, biotech, medtech, health-plan and digital-health customers can find the right doctors, run better clinical trials, engage key opinion leaders and keep provider information accurate. Its stated mission is to create a healthier future by making healthcare information and evidence-based medicine accessible globally.
Lyfegen
Lyfegen is a Swiss health-tech company that builds software to manage value-based drug pricing and rebate agreements. Its platform helps health insurers, governments, hospital payers, pharmaceutical firms and medical device makers automate complex rebate contracts, run pricing simulations and tap the world's largest library of value-based agreements - reducing administrative burden while helping patients access innovative therapies.
Proprio
Proprio is a Seattle medical technology company building an AI-powered surgical navigation platform, Paradigm, that uses light field imaging, computer vision, and machine learning to give surgeons a continuous, radiation-free 3D view of anatomy during spine surgery. Spun out of the University of Washington in 2016, the company fuses live intraoperative sensing with preoperative scans - a capability it calls Volumetric Intelligence - to improve precision, capture surgical data, and build a foundation model for surgery.
Reveal HealthTech
Reveal HealthTech is a New York-based AI transformation partner for U.S. healthcare and life sciences organizations. Founded in 2023 and incubated by W Health Ventures and 2070 Health, the company pairs clinical expertise with engineering and design to turn AI concepts into deployed products for hospitals, pharma, and digital health innovators. Its flagship products include BioCanvas for clinical trial recruitment, Prism AI for workflow automation, and CareIQ for care coordination. Reveal raised a $7.2M Series A led by Leo Capital in September 2025 and runs teams across the U.S. and Bengaluru, India.
Cozeva
Cozeva is a cloud-based, real-time data platform built by Applied Research Works that helps health plans, physician organizations, and their partners move from fee-for-service to value-based care. It unifies quality measurement (HEDIS, Medicare Stars, P4P), risk adjustment (HCC coding and recapture), and population health analytics in a single, EHR-interoperable system that lets clinicians act on care gaps at the point of care. Founded in 2012 and based in San Ramon, California, Cozeva serves 25M+ lives and 97,000+ providers, holds NCQA and HITRUST certifications, and earned Best in KLAS recognition in 2025 and 2026. In October 2025 it merged with Vatica Health to combine top-ranked quality and risk-adjustment platforms.
Heartflow
Heartflow is a Silicon Valley medical technology company that uses AI and computational fluid dynamics to turn a standard coronary CT scan into a personalized, color-coded 3D model of a patient's heart. Its FFRCT, Plaque and RoadMap analyses help cardiologists diagnose and manage coronary artery disease non-invasively, reducing the need for invasive angiograms. Founded in 2007 and headquartered in San Francisco, Heartflow has analyzed hundreds of thousands of patients across more than 1,500 U.S. hospitals and went public on the Nasdaq (HTFL) in August 2025.
Collectly
Collectly is a San Francisco-based healthcare fintech that automates the patient side of revenue cycle management. Its AI platform plugs into more than 20 EHR and practice-management systems to run digital billing, eligibility checks, cost estimates, payments and follow-up, so medical groups collect more, faster, with fewer staff hours. Founded in 2017 and a Y Combinator graduate, Collectly says it serves 3,000+ healthcare facilities and has processed over $1 billion in patient payments. In 2025 it launched Billie, a 24/7 AI agent that answers patient billing questions and takes action across voice, chat, text and email.
Harae Dx Corp.
Harae Dx Corp. is a Pleasanton, California medical device startup building what it calls the world's smallest portable, automated system for early cancer detection. Founded in 2021 by serial medtech entrepreneur Sanjeev Saxena, the company pairs a proprietary lab-on-a-disc centrifugal microfluidic platform with a biomarker panel exclusively licensed from Lawrence Livermore National Laboratory to deliver a non-invasive early breast cancer test that returns results in roughly 30 minutes - without shipping samples to a third-party lab. Backed by SOSV/HAX and Fusion Fund, Harae Dx aims to make low-cost cancer screening portable enough to run at the point of care.
Human Longevity, Inc.
Human Longevity, Inc. is a San Diego- and South San Francisco-based genomics and precision-health company founded in 2013 by genome-sequencing pioneer J. Craig Venter, Peter Diamandis, and Robert Hariri. It pairs clinical-grade whole genome sequencing with whole-body MRI, hundreds of blood biomarkers, and AI analytics - delivered through its Health Nucleus platform - to detect cancer, cardiovascular disease, and other age-related conditions before symptoms appear. After a decade building one of the world's largest longitudinal genotype-phenotype datasets, the company in 2026 launched a $599 clinical-grade whole genome report and spun out Human Life Foundation Models, Inc. to build large-scale AI foundation models for longevity science.
Muse by Interaxon Inc.
Muse, made by Toronto-based Interaxon Inc., is a brain-sensing headband that turns clinical-grade EEG into a consumer wearable. First shipped in 2014, Muse reads your brainwaves and, through a companion app, gives real-time audio feedback to guide meditation, track sleep, and train focus. The company has since layered on fNIRS and SpO2 sensing (Muse S Athena, 2025) and an AI brain-health platform trained on more than a billion minutes of EEG data, positioning Muse at the intersection of consumer wellness and clinical neuroscience.
Lamar Health
Lamar Health is a San Francisco software company that automates the paperwork behind expensive specialty medications. Its AI-driven platform handles unified intake, insurance verification, clinical and payor requirement checks, and prior authorization submission and tracking for specialty pharmacies, infusion clinics, and home infusion pharmacies - the drugs that average around $70,000 per patient per year. Founded by Ph.D. geneticist Eesha Sharma and backed by Y Combinator (W21), Lamar aims to get patients on therapy in days instead of weeks without forcing providers to add headcount.
Radial
Radial (Radial Analytics, Inc.) is a Concord, Massachusetts healthcare technology company that builds AI-driven decision support software for value-based care. Its flagship platform, Smart Placement, uses machine learning and natural language processing to help hospitals, health plans, and accountable care organizations decide - in real time - which patients can safely recover at home instead of in a skilled nursing facility after a hospital stay. Founded in 2014 by former Locately co-founders Thaddeus Fulford-Jones and Eric Weiss alongside physician Anant Vasudevan, Radial applies 'nudge theory' at clinical crossroads moments to lower costs and improve outcomes without overriding clinician judgment.
Verse Medical
Verse Medical is a New York-based healthtech company building the software infrastructure for in-home healthcare, starting with durable medical equipment (DME) and supplies. Its platform helps hospitals, payors, and care teams order and coordinate equipment like catheters, wound dressings, and diabetes supplies - replacing a fax-and-phone-call process with real-time insurance verification, medical-record-level documentation checks, and centralized order tracking. Founded in 2018 by Dhaivat Pandya out of Y Combinator, Verse today works with many of the largest U.S. health systems and is backed by investors including SignalFire, Sapphire Ventures, General Catalyst, and Abstract Ventures.
Unlearn.AI
Unlearn.AI is a San Francisco biotech-AI company that builds disease-specific machine learning models to generate digital twins of clinical trial participants - longitudinal predictions of how each patient would have fared on placebo. Folded into a statistical method called PROCOVA and a trial design called TwinRCT, the approach lets sponsors shrink control arms by up to a third, so more patients receive the experimental drug while trials reach answers faster. Founded in 2017 by physicists Charles Fisher, Aaron Smith and Jon Walsh, the company has raised about $130M and earned a first-of-its-kind EMA qualification for an AI-based method to reduce sample size in pivotal trials.
Alara Imaging
Alara Imaging is a San Francisco healthcare technology company building a private compute platform for radiology. Its flagship product, the Alara Medical Imaging Gateway, is edge-orchestration software that sits inside a hospital and moves imaging data securely and bidirectionally between facilities and the cloud. Founded out of UCSF research, Alara serves as a CMS measure steward, giving health systems a HITRUST-certified, HIPAA- and SOC 2-compliant way to calculate and report new radiology quality measures - including a CMS-endorsed measure to standardize CT radiation doses and reduce avoidable cancer risk.
Cadence
Cadence is a New York-based clinical technology company that helps health systems deliver continuous, proactive care to patients with chronic conditions at home. It pairs FDA-cleared connected devices that track vitals with an AI-powered care platform and a 24/7 clinical team, so doctors can catch problems - rising blood pressure, fluid buildup, glucose swings - before they become emergencies. Cadence partners with more than 20 leading U.S. health systems and supports tens of thousands of patients across dozens of states, targeting chronic diseases such as heart failure, hypertension, type 2 diabetes, and COPD.
Garner Health
Garner Health is a New York-based healthcare technology company that analyzes billions of medical claims to identify the highest-performing doctors, then pairs that data with employer-funded financial incentives so employees can see top providers at a fraction of the out-of-pocket cost. Founded in 2019 by Nick Reber, the company combines a member-facing care navigation app and concierge with a provider analytics engine (Garner DataPro / Garner Research Agent) used by employers and health plans to cut healthcare spend while improving outcomes.
Numen
Numen (formerly Cleancard) is a San Francisco biotech building rapid at-home cancer screens that read like a pregnancy test. By combining synthetic biology, machine learning, and computer vision, its platform detects multiple cancer biomarkers from a single urine sample in about 30 minutes, with no lab machinery required. Founded by Rhodes Scholars Thomas Carroll and Luca Springer, the company's first screens target prostate, bladder, and ovarian cancer, with a mission to drive cancer mortality toward zero.
Spring Health
Spring Health is a New York-based digital mental health company that uses machine learning to match people with the right care - therapy, coaching, medication, or self-guided tools - and deliver it through employers and health plans. Founded in 2016 by Yale graduates, its 'Precision Mental Healthcare' approach reframes the old employee assistance program (EAP) into a measurable, outcomes-driven benefit. Now valued at $3.3 billion, Spring Health reaches more than 20 million people worldwide through employers, payers, and channel partners.
xCures Inc.
xCures is an AI-powered health-data platform that automatically retrieves medical records from any care site in the United States, then structures, normalizes, and validates that messy, unstructured data into searchable, source-traceable clinical insights. Born in oncology, it generates regulatory-grade real-world evidence, AI-built clinical checklists, and natural-language patient summaries that help researchers, biopharma, advocacy groups, and clinicians understand each patient's full medical journey - and run continuously learning 'virtual trials' across all patients, all treatments, all the time.
DeepLook Medical
DeepLook Medical is a Scottsdale, Arizona medical imaging company whose FDA-cleared software, DL Precise, helps radiologists see and measure suspicious lesions that hide inside dense breast tissue. Using proprietary shape-recognition algorithms that overlay directly on existing imaging systems, the tool delivers single-click segmentation across mammography, ultrasound, CT and MRI. Led by CEO Marissa Fayer, the company is in commercial use at major U.S. health systems and closed a Series A led by Xcellerant Ventures in 2024.
Hone Health
Hone Health is a New York-based telemedicine clinic built for preventive and longevity care. It pairs at-home and in-person testing of 40+ biomarkers with physician-guided treatment plans for hormone optimization, menopause, weight loss, sexual health, thyroid and more, delivered nationwide on a subscription model starting around $129/month. After raising a $33M Series A in January 2025 and acquiring in-home care company ivee, Hone has tested 300,000+ patients and treats roughly 55,000 active members.
Tomorrow Health
Tomorrow Health is a New York-based health technology company that connects providers, payors, and durable medical equipment (DME) suppliers on a single platform so home-based care can be ordered, routed, and paid for without the usual paperwork chaos. Founded by Vijay Kedar and Casper co-founder Gabriel Flateman, it uses intelligent automation - and, increasingly, AI - to turn a process that historically took hours of faxes and phone calls into something closer to a clean digital order, serving more than 100 health plans and managing over $100 million in DME spend.
Clover Health
Clover Health is a Medicare Advantage insurer that runs on software. Its flagship platform, Clover Assistant, feeds physicians AI-driven, point-of-care insights drawn from millions of health data points so they can catch chronic disease earlier and treat it cheaper. After a rocky SPAC debut in 2021, the company reached adjusted EBITDA profitability in 2024, grew Medicare Advantage membership past 150,000, and is guiding to its first-ever full-year GAAP net income in 2026.