Derk Arts is a Dutch physician-turned-entrepreneur and the founder and CEO of Castor, a clinical-trial software company he started in 2012 after coding the first version of its Electronic Data Capture platform himself. Trained as a medical doctor and epidemiologist with a PhD, he built Castor to make clinical research more inclusive, patient-centric, and data-driven. The platform now supports thousands of trials across roughly 90 countries and was used by the World Health Organization for its Solidarity Trial. Castor has raised more than $60 million, including a $45 million Series B in 2021, and Arts is a recognized voice on decentralized trials, eConsent, and the responsible use of AI in research.
Adyen is a Dutch financial technology company that provides a single, end-to-end platform for accepting payments online, in apps, and in stores. Founded in Amsterdam in 2006, it operates as a licensed acquiring bank and connects merchants directly to card networks and local payment methods across the globe. Adyen powers checkout and embedded financial products for enterprises such as Uber, Spotify, eBay, Booking.com, McDonald's, and Microsoft, and is publicly listed on Euronext Amsterdam.
Zlatan Menkovic is the CEO and co-founder of Scaler, an ESG data platform helping real estate managers measure, report, and cut the carbon footprint of their buildings. A Dutch product designer turned repeat founder, he built Scaler after years shaping products at Uber and Uber Freight and an earlier startup, PeerReach. Scaler now serves roughly 30 clients overseeing more than $350 billion in assets and raised a $10M Series A in 2024 led by Plural. Menkovic's pitch is blunt: if you want global impact, start with the buildings we already live and work in.

Gergely Orosz is the Hungarian-born, Amsterdam-based author behind The Pragmatic Engineer, the #1 technology newsletter on Substack with over 1 million readers. A former engineering manager at Uber who helped build payments infrastructure processing $65B+ annually, he left Big Tech in 2021 to write independently. He covers software engineering careers, Big Tech culture, and the AI-driven transformation of the industry - earning $1.5M+ per year from subscriptions alone, with zero ads or sponsors.