Khanh Nguyen - CEO, Cozeva
Chief Executive Officer, Cozeva • PharmD, UCSF
She built a platform that now touches 25 million patient lives. Then she sold it for $480 million. Khanh Nguyen runs Cozeva - the "operating system" that payers and providers both actually use, at the moment they need it most. A pharmacist who decided the real problem was data.
There's a scene that plays out in doctor's offices across California thousands of times a day. A physician opens a patient chart, glances at what they know, and makes a decision - without ever seeing the full picture of what that patient's insurance data, lab history, or care gaps look like. That gap, between what a provider knows and what they need to know, is the business Khanh Nguyen built her career around closing.
Nguyen trained as a pharmacist at UCSF - one of the country's top pharmacy schools. But her path veered fast into the messy middle of American healthcare finance: managed care, payer contracts, quality metrics, population health. At Hill Physicians Medical Group, she served as Vice President of Pharmacy Services and Population Health, building a care model aligned to the Quintuple Aim. That's the framework that adds health equity and clinician wellbeing to the original Triple Aim of better outcomes, better experience, lower cost. Two extra things most organizations still treat as optional.
In October 2022, Applied Research Works (ARW) appointed her CEO of Cozeva. The platform had a clear pitch: a single, unified system for value-based care that combined real-time data exchange, quality performance metrics, and risk adjustment into clinical workflows. Not a dashboard clinicians ignore. A tool they actually use, at the point of care, when decisions happen.
Nguyen inherited a company with a sharp product and a sharper vision. Cozeva's internal mission statement is nine words: "Building trust across the healthcare ecosystem." The vision is even more direct: "To be the operating system for value-based care." In an industry notorious for buzzword excess, that compression is a choice. It signals that Nguyen is building infrastructure, not apps - the layer everything else runs on top of.
The bet paid off in a measurable way. In 2024, the Integrated Healthcare Association's board voted to make Cozeva the exclusive analytics partner for all of IHA's performance measurement programs, beginning 2025. The IHA's flagship program - Align. Measure. Perform. (AMP) - serves over 70 provider organizations across California and is considered a national model for multi-payer alignment. Getting picked as the sole platform for that program isn't a partnership announcement. It's an endorsement of the architecture.
Cozeva was founded to enable payers and providers with the most comprehensive operating system for value-based care. By joining Vatica, we are extending that platform beyond technology - uniting actionable data, advanced analytics, and clinical services into a single, integrated solution.
- Khanh Nguyen, on the Vatica Health merger, November 2025On October 31, 2025, Vatica Health - backed by Frazier Healthcare Partners - closed its merger with Cozeva, in a deal reported by Axios at approximately $480 million. The combination was unusual: both companies held the top ranking in their respective categories. Vatica's risk adjustment platform had earned the Best in KLAS designation for its category. Cozeva held the same designation for quality management. Two #1 KLAS platforms, merged into one.
Nguyen framed it not as an exit but as an extension. In her public statement, she described moving "beyond technology" - using the merger to add clinical services and real-world care delivery to the platform's analytical capabilities. The language tracks with her career-long pattern: start with data, build toward care.
By February 2026, the recognition continued. Cozeva earned Best in KLAS 2026 for Risk Adjustment: Point-of-Care and In-Home Health Assessments, with a score of 91.2 out of 100 - the highest in its competitive class.
Nguyen's official bio says she brings "over 15 years of experience pioneering payer-provider collaborations." That's the kind of phrase that sounds like LinkedIn filler until you consider what it actually means to spend 15 years at the intersection of health insurers and doctors - two entities whose incentive structures were, for most of American healthcare history, designed to conflict.
Payers want to pay less. Providers want to get paid more. The gap between them generated decades of paperwork, friction, and misaligned care. Value-based care is the attempt to align them around outcomes rather than volume. Nguyen spent her career building the systems that make that alignment possible in practice, not just in policy documents.
That's why her quote on translating policy to execution resonates: "They need partners who can translate policy into execution - driving accurate, prospective insights at the point of care and scaling with confidence." It's not a marketing line. It's a description of what her teams actually do.
"We are excited to deepen our partnership with IHA and support the evolution of their innovative programs, which are at the forefront of national multi-payer alignment and value-based payment efforts."
- Khanh Nguyen, following IHA's selection of Cozeva as sole analytics partner, 2024Doctor of Pharmacy (PharmD) - University of California, San Francisco, School of Pharmacy. One of the country's top pharmacy programs. Where clinical rigor meets systems thinking.
VP, Pharmacy Services & Population Health - Hill Physicians Medical Group. Launched a care model aligned to the Quintuple Aim. Built high-performing teams delivering payer-provider collaborations across California.
Appointed CEO, Applied Research Works (ARW) / Cozeva. Took the helm of the platform with a vision to become the operating system for value-based care. "I am excited and humbled to assume the position of CEO at ARW."
IHA Partnership - Cozeva selected by Integrated Healthcare Association as analytics partner for California's Advanced Primary Care Initiative, focused on the California Core 4.
NCQA Keynote - Delivered keynote address at NCQA Health Innovation Summit 2024 on digital quality. Spoke at the Women in Quality Reception. Cozeva's platform earns Best in KLAS for quality management.
IHA Exclusive Partnership - IHA Board of Directors selects Cozeva as sole analytics partner for all AMP performance measurement programs beginning 2025 - a national model for multi-payer alignment.
$480M Merger with Vatica Health - Cozeva merges with Frazier Healthcare-backed Vatica Health, combining two #1-rated Best in KLAS platforms. TripleTree served as financial advisor to Cozeva.
Best in KLAS 2026 - Cozeva earns top ranking for Risk Adjustment: Point-of-Care & In-Home Health Assessments with a score of 91.2/100 - the highest in its competitive class.
The phrase "operating system for value-based care" is doing a lot of work. Nguyen uses it deliberately. An operating system doesn't do any one thing - it's the layer that makes all the other things possible. It handles the hardware so the applications don't have to think about it. Cozeva is trying to be that layer for healthcare: the thing that processes real-time data streams from payers and providers so clinicians can focus on patients.
In practice that means: care gap analysis surfaced in clinical workflows, HCC diagnosis confirmation at the point of care, automated chart abstraction using NLP, real-time dashboards for quality performance, and multi-payer contract tracking from a single platform. The tech stack includes Amazon AWS, Kubernetes, Redshift, Aurora, Node.js, and AI tooling. The result is a platform that scored 91.2 out of 100 in KLAS evaluations - the top mark in its class.
After the Vatica merger, Nguyen described the expanded vision: moving "beyond technology" to combine data, analytics, and clinical services. That's the next phase - not just showing providers what's missing in a patient's care, but helping close the gap through clinical capacity. The platform becomes a care delivery layer, not just a reporting layer.
The scale that Cozeva now operates at - 25 million lives, 97,000 providers - means that marginal improvements in care gap closure or risk coding accuracy compound into massive population health outcomes. That's why Nguyen's language is always about trust and collaboration, not dashboards and reports. The real output is what happens in the room between a doctor and a patient.
Clinical data synchronized across payers and providers at the point of care - not after the encounter, during it.
HEDIS quality programs, risk adjustment, HCC capture, and MACRA reporting unified on a single multi-payer platform.
Natural language processing for unstructured clinical data. Automated chart abstraction. Predictive analytics for population health management.
The mission in nine words: "Building trust across the healthcare ecosystem." Two sides that historically didn't collaborate, now on the same platform.
"They need partners who can translate policy into execution - driving accurate, prospective insights at the point of care and scaling with confidence."
- Khanh Nguyen, CEO of Cozeva, 2026Nguyen holds a Doctor of Pharmacy from UCSF - making her a PharmD CEO in a world of MBAs. The clinical lens shows up in how she frames every product decision.
Cozeva's nine-word mission - "Building trust across the healthcare ecosystem" - was deliberate compression. In healthcare, trust is the actual hard problem.
The $480M Vatica merger brought together two companies that both held the #1 KLAS ranking in their category simultaneously. That combination is rare.
Cozeva scored 91.2 out of 100 in 2026 KLAS evaluations - the highest score in its competitive class. Every point in KLAS scoring represents real customer feedback.
At Hill Physicians, Nguyen launched a care model aligned to the Quintuple Aim before most health systems could spell it. Health equity and clinician wellbeing as core metrics, not add-ons.