care-management
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Ascertain wants to get healthcare out of the hold queue
The company built with Northwell Health is putting AI to work on authorizations, payer portals, and the administrative errands that keep care waiting. Its wager: the useful revolution starts with the paperwork.
VirtualHealth and the fine art of making healthcare talk
A patient can have a doctor, a health plan and a mountain of records, yet still fall through the gaps. VirtualHealth built HELIOS to connect the work around that patient - a proposition now carried forward by Elligint Health.
Wellframe puts the nurse within reach.
The appointment ends. The questions do not. Wellframe gives health plans a way to keep a human connection alive between visits - and its hardest work happens behind the screen.
Flagler Health is treating the clinic
The founders considered buying medical practices. Instead, they built software to handle the work between appointments - and raised $50 million to take it further.
The Helper Bees turns insurance promises into help at home
A meal, a ride, a grab bar: small things can decide whether someone stays at home. The Austin company builds the machinery that gets insurance benefits through the front door.
Hera takes the second job out of caring for your parents
The doctor writes the plan. Someone still has to make it happen. Hera pairs families with a dedicated care expert, backed by software and paid through Medicare for eligible patients.
Zyter|TruCare and the Trouble with the Next Step
Healthcare has plenty of software that knows what should happen. Zyter|TruCare is betting on the less glamorous business of making the next step happen - across people, policies and machines.
MHK and the Hidden Cost of a Handoff
A health plan can have capable people and still leave thousands of disputes waiting. MHK’s wager is that better care begins with fixing the work between the people.
The Voice on the Other End of the Care Gap
Ellipsis Health spent years teaching software to hear signs of distress in a voice. Then it gave that software a job: call patients, listen, and help care teams reach the people they keep missing.
Cricket Health Bet on the Hours Before the Emergency
Kidney failure is often treated as a sudden event, though the clues arrive years earlier. Cricket Health built a business around finding those clues - and giving patients time to choose what happened next.
The Diabetes App That Found the Real Patient Was the Care Team
Welkin Health began by coaching people with diabetes. Then its founders noticed the harder problem: the people delivering care were trapped between spreadsheets, inboxes and software that could not bend.
Birdie wants the care visit to end when the carer leaves
The homecare software company found its market by giving up on a family sensor product. Now it is taking on the paperwork that follows carers home.
HealthEdge Is Building the Operating System Health Plans Were Too Scared to Replace
The dullest machinery in American healthcare may be the most expensive to leave untouched. HealthEdge spent 20 years turning claims rules, care workflows and provider records into one payer platform - then merged with the operator that knew how to move insurers onto it.
Lightbeam Found Billions in Healthcare’s Messy Middle - Then Turned a Customer Into Its Operator
Hospitals do not need another dashboard. They need to know who to call before lunch. Lightbeam built a business around that unglamorous handoff from data to action - and says its customers have generated more than $5 billion in gross savings along the way.
Innovaccer Threw Away 70% of Its Revenue - Then Built Healthcare’s Missing Data Layer
The founders killed a working analytics business, lived inside an Iowa hospital and spent more than $100 million connecting healthcare’s stubborn software islands. Now their $3.45 billion bet is that the same plumbing can make AI useful - not merely impressive.
Medecision Survived a Rough IPO. Now It Wants Health Plans to Stop Admiring Dashboards and Start Acting.
A basement-born medical software company went public, endured what its founder called a terrible ride, and sold for $121 million. Nearly four decades after launch, Medecision is betting that healthcare’s next breakthrough is not another dashboard - it is turning messy data into the next useful action.
Carenet Health Turned Healthcare’s Messiest Phone Calls Into a 500-Client Operating System
Carenet’s bet is that the most expensive gap in American healthcare is often a missed call, a confusing benefit or an appointment never booked. It sells the people, software and clinical workflows to close that gap - at a scale that now reaches one in three Americans.
Evolent
The company betting that the most expensive corner of American medicine - cancer, cardiology, and back surgery - can be run better when the people paying for care and the doctors delivering it are finally pulling in the same direction.
Autonomize AI
Autonomize AI is an Austin-based healthcare technology company building an AI-native platform - the 'Autonomize Intelligence Platform' - that embeds governed, agentic AI directly into clinical and operational workflows for health plans, providers, and life sciences organizations. Founded in 2022 by Ganesh Padmanabhan and Kris Nair, the company turns mountains of unstructured healthcare data into structured intelligence, deploying pre-built AI agents and copilots for tasks like utilization review, prior authorization, care management, and clinical chart review. It says its systems save roughly 36,000 clinical hours per month across Fortune 100 healthcare customers, and it raised a $28 million Series A in June 2025 led by Valtruis, The Cigna Group Ventures, and Tau Ventures.
Laguna Health
Laguna Health is a healthtech company building conversational AI for care teams. Its platform, anchored by the Laguna Companion co-pilot, the Laguna Insight analytics layer, and the LISA family of AI agents, listens to member calls, automates clinical documentation, and surfaces context so care managers - typically nurses - can spend less time on paperwork and more time supporting patients recovering after hospital stays. Founded in 2020 by Yoni Shtein and Yael Adam, the company serves health plans, payers, and virtual care organizations from offices in Tel Aviv and New York.
Tucuvi
Tucuvi is a clinical voice AI company that builds and operates an AI care management platform for hospitals and health systems. Its voice AI agent, LOLA, safely conducts patient phone conversations, runs clinical and care-coordination workflows such as post-surgical follow-ups and chronic care management, and escalates to human clinicians when needed. Founded in Madrid in 2019 by biomedical engineers Maria Gonzalez Manso and Marcos Rubio, Tucuvi is the first AI platform to earn European Class IIb Software as a Medical Device certification for both its voice agent and its care management platform. It serves more than 60 healthcare organizations across Europe, the UK and the US and has monitored over a million patients.
Vytalize Health
Vytalize Health is a value-based care enabler and Accountable Care Organization (ACO) that helps independent primary care physicians care for Medicare patients while lowering the total cost of care. Founded in 2014 and headquartered in Hoboken, New Jersey, it pairs a physician-built clinical data platform (Vytal Insights) with a wraparound clinical team and virtual clinic (Vytal Care) so small practices can succeed in Medicare's advanced value-based programs like ACO REACH and MSSP. The company serves hundreds of thousands of Medicare beneficiaries across dozens of states and was named the No. 1 fastest-growing private company in America by Inc. in 2024.
Acentra Health
Acentra Health is a McLean, Virginia healthcare technology and clinical services company formed in 2023 from the merger of CNSI and Kepro. It builds Medicaid and Medicare systems, care management platforms, and quality-oversight services for state and federal government health programs, combining public-sector software with clinical staff who review authorizations, assessments, and appeals. Backed by The Carlyle Group, it employs roughly 3,300-3,400 people across the U.S. and India.
GenieMD
GenieMD is a San Ramon, California virtual care company that sells a single, white-label platform folding together telehealth, remote patient monitoring, remote therapeutic monitoring and chronic care management - plus built-in e-prescriptions, lab integration and CPT billing reports. Founded in 2010 by Stanford-trained engineer Soheil Saadat, it sells to hospitals, health systems, group practices, insurers, ACOs and employers, and in 2026 launched HelloGenie, a free AI doctor that hands patients off to real board-certified physicians when actual care is needed. Frost & Sullivan named it 2024 Company of the Year for virtual chronic disease management.
Karoo Health
Karoo Health is an Albuquerque, New Mexico company building tech-enabled, value-based cardiovascular care. It pairs wraparound care teams - nurses, dietitians, pharmacists, health coaches and advanced-practice providers - with Kohere.ai, a proprietary platform that aggregates patient data, flags risk and coordinates communication. The model helps cardiology networks, health systems and health plans move from fee-for-service to value-based arrangements, aiming to improve heart-patient outcomes while lowering the cost of care.
Quadrant Health
Quadrant Health builds AI voice and agentic workflows that run natively inside the electronic health records clinicians already use - Epic, athenahealth, eClinicalWorks and Medent. Founded in 2021 out of Y Combinator's Winter 2021 batch, the company started by analyzing EHR and messaging data to predict disease before it occurs, then pivoted into AI agents that handle the operational grind of a medical practice: an AI scribe that drafts EHR-ready notes in real time, and administrative agents that answer calls 24/7, book appointments, collect intake, process refill requests and close care gaps in 20+ languages. Led by co-founder and CEO Anin Sayana, Quadrant sells HIPAA- and SOC2-compliant software to providers, payers and life sciences organizations.
DeLorean Artificial Intelligence
DeLorean Artificial Intelligence is a Palm Beach, Florida-based healthcare AI company that builds predictive and interventive intelligence to forecast chronic disease and recommend next-best clinical actions before a patient gets sicker. Its flagship Medical AI platform, MARTI, analyzes structured and unstructured health records to predict events like hospitalizations and disease progression - and is described as the first medical AI to be biologically validated by independent third parties. Founded in 2019 by Dr. Severence MacLaughlin, the company also applies its predictive engine to sales/CRM, life sciences, financial services and other industries.
Diagnostic Robotics
Diagnostic Robotics is an AI healthcare company building medical-grade triage and clinical-prediction software for health plans and providers. Its models, trained on tens of billions of claims data points and nearly 100 million patient visits, forecast avoidable ER visits, congestive heart failure deterioration and serious mental illness, then steer patients into the right care pathway. Founded in 2017 by Kira Radinsky, Jonathan (Yonatan) Amir and Moshe Shoham, the company is a Mayo Clinic Platform portfolio company and closed a $45M Series B in 2022.
Digital Health Strategies
Digital Health Strategies is a Washington, DC-based healthcare data and technology company that helps hospitals and health systems grow what it calls their Share of Health. Its AI-powered platform identifies the existing patients, donors, and plan members most likely to benefit from a service, then activates them through personalized communications wired into clinical and operational workflows - closing care gaps, lifting service-line volume, growing membership, and raising philanthropic dollars. Founded in 2014 by John Simpson and Ben Texter, both alumni of Blue State Digital, the firm works with leading systems including Johns Hopkins, Geisinger, Providence, Scripps, and Hackensack Meridian Health.
Greater Good Health
Greater Good Health is a Los Angeles-based healthcare company rethinking primary care for seniors. It runs value-based primary care clinics and clinical programs built around a nurse practitioner-centric care model, designed to manage complex Medicare populations through proactive, preventive, whole-person care. The company partners with health plans and risk-bearing organizations to expand access where physician shortages have left aging patients underserved.