spine-surgery
(5)
DuraStat
DuraStat is an Austin, Texas medical device company that makes a purpose-built surgical instrument for repairing tears in the dura - the membrane surrounding the brain and spinal cord. Its handheld device automates suture passage so surgeons can create precise, watertight closures to prevent cerebrospinal fluid (CSF) leaks, even through the limited access typical of spine and neurosurgical procedures. Invented by practicing spine surgeons, DuraStat and its companion fascial-closure device TissueStat are stocked in surgical facilities across all 50 U.S. states, and in late 2024 the company entered an exclusive U.S. commercial partnership with Medtronic.
Proprio
Proprio is a Seattle medical technology company building an AI-powered surgical navigation platform, Paradigm, that uses light field imaging, computer vision, and machine learning to give surgeons a continuous, radiation-free 3D view of anatomy during spine surgery. Spun out of the University of Washington in 2016, the company fuses live intraoperative sensing with preoperative scans - a capability it calls Volumetric Intelligence - to improve precision, capture surgical data, and build a foundation model for surgery.
Illuminant Surgical
Illuminant Surgical is a Culver City / Los Angeles medical device startup building Skylight, a real-time anatomical projection system that displays a patient's internal imaging directly onto their skin during surgery. Using AI, computer vision and dynamic projection mapping - technology borrowed in part from entertainment-industry projection artists - the company aims to give surgeons a kind of 'x-ray vision' for spine surgery, cancer biopsies and other image-guided procedures without forcing them to look away from the operating field.
Nervio
Nervio is an Israeli-American digital health company building AIM, an AI-powered intraoperative neuromonitoring (IONM) system that turns raw surgical signal data into real-time alerts and recommendations. Founded in 2020 by brothers Dr. Omer Zarchi and Nir Zarchi, the company aims to prevent avoidable paralysis and nerve injury during spine and neurosurgery at a time when the number of surgeries is climbing and the pool of expert neurophysiologists is shrinking. Nervio operates from Nashville, Tennessee with an R&D center in Israel, and its technology has been developed with input from dozens of neurophysiologists across more than 1,000 surgical cases.
Cerapedics Inc.
Cerapedics is a commercial-stage ortho-biologics company that engineered a synthetic 15-amino-acid peptide, P-15, to coax the body into building bone faster. Its FDA-approved i-FACTOR is used in cervical spine fusions, and its 2025 PearlMatrix approval made it the first and only proven bone growth accelerator cleared for lumbar fusion.