A Los Angeles startup building Skylight - a smart surgical lamp that paints a patient's insides onto their skin, in real time, as the surgeon cuts.
Here is a strange fact about modern surgery: a surgeon operating on your spine spends a meaningful chunk of the procedure not looking at you. They are looking at a monitor mounted across the room, glancing back and forth between a glowing scan and the open field in front of them, doing the mental gymnastics of translating a flat, grayscale image into the three-dimensional body under their hands. It works. It has worked for decades. But it is, if you think about it, a slightly ridiculous way to do the most precise work a human being can do.
Illuminant Surgical's proposition is to delete the middleman. Instead of putting the imaging on a monitor and asking the surgeon to look away, put the imaging on the patient. The company's flagship system, Skylight, is essentially a smart surgical lamp: it takes a patient's medical imaging and projects the relevant anatomy directly onto their skin, aligned to their actual body, updating in real time. Co-founder and co-CEO Eldrick Millares describes it as displaying images on the skin "to tell you exactly what's underneath as you're cutting" - or, more vividly, as "a live tattoo that moves with the patient."
That phrase - a live tattoo - is worth sitting with, because it quietly names the genuinely hard part. Projecting an image onto a flat wall is a solved problem; any conference room can do it. Projecting an image onto a curved, breathing, occasionally bleeding human body, and keeping that image locked precisely to the anatomy beneath the surface as the body shifts, is not. That is a computer-vision problem, a depth-mapping problem, and a registration problem all at once. Skylight's answer comes in two named pieces, which we'll get to. The point for now is that the elegant idea - just put the picture on the patient - hides a stack of difficult engineering, and the difficult engineering is the moat.
The most powerful technology is the kind you don't have to think about using.
On-skin augmented reality that asks the surgeon to change nothing - no goggles, no headset, no new way of standing or holding a tool.
A real-time anatomical projection system - a smart surgical lamp - that displays a patient's imaging directly onto their skin during spine surgery and interventional access, so the surgeon never has to look away from the field.
Non-invasive patient registration. Adhesive skin markers plus computer vision align the medical images to the patient's anatomy in real time - no pins, no clamps, no invasive fiducials.
Depth-adaptive projection that renders anatomical detail on the skin surface, dynamically adjusting for patient movement and body contours so the picture stays true as things move.
The earlier camera-projector prototype: low-cost commodity hardware and a markerless, surface-topography alignment algorithm projecting guidance onto the skin. The proof of concept behind the platform.
SkinMatch uses adhesive markers and computer vision to lock the patient's imaging to their actual body. Setup is non-invasive and takes minutes.
LightScreen paints the relevant anatomy onto the skin, adapting for depth and contour so the projection reads accurately across the surface.
As the patient breathes and shifts, the system keeps the image aligned - the "live tattoo" that moves with the body while the surgeon keeps their eyes down.
Illuminant Surgical was founded in 2021 by Eldrick Millares and Dr. James Hu, who met as classmates at Stanford and now run the company as co-CEOs - one leaning engineering, one leaning medicine. That pairing matters in medical devices, where the failure mode is usually a beautiful piece of technology that no clinician can actually fit into a real operating room, or a clinically sound idea that no one can actually build.
The company's most quietly clever decision was geographic. It planted itself in Los Angeles - Culver City, specifically - not because LA is a traditional medtech hub, but because it is the world capital of a very specific and very relevant skill: projection. The people who make images dance across live performers, stadium floors and theme-park rides are exactly the people you want if your product is real-time projection mapping onto a moving body. One engineer on staff previously built projection technology for performers in the Disney Imagineering tradition; that same craft, pointed at a spine instead of a stage, becomes surgical navigation. The lesson is a good one for any founder: the hard technical problem in your field may already be solved cold in an industry that looks nothing like yours.
Hu is candid about where he thinks this all goes. "I think open surgeries are going to become more and more of a rare procedure, limited to extremely complex cases," he has said. The mechanism behind that claim is straightforward enough to be credible: better guidance makes small incisions safer, and safer small incisions make big ones unnecessary. Skylight starts with the spine, but the roadmap runs toward lung cancer biopsies and other percutaneous, image-guided access - anywhere a doctor needs to hit a target under the skin without a large opening to see it.
I think open surgeries are going to become more and more of a rare procedure, limited to extremely complex cases.
Announced April 2026 and led by Wing 2 Wing Ventures - with roughly half the total coming from federal science agencies rather than venture capital.
The structure is as interesting as the size. About half of the $8.4 million is grant funding from the National Science Foundation, the National Cancer Institute and the National Institute on Aging. For a deep-tech company, that split does double duty: non-dilutive capital that keeps the cap table clean, and a credibility stamp from institutions that fund science rather than hype. It is a reminder that for hard-technology startups, non-dilutive funding is not a consolation prize you take when the VCs pass - it can be a deliberate strategy.
See Skylight in action and hear the founders explain the technology on Illuminant Surgical's official channels:
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