precision-fermentation
(9)
Bel Group
How a Jura cheesemaker became a 120-country snacking machine - and why a 160-year-old family business is now spending it on regenerative farms and lab-made dairy.
Helaina
Helaina is a New York-based biotechnology company using precision fermentation to produce human-equivalent bioactive proteins. Its first commercial product, effera, is a human-identical lactoferrin made in yeast that matches the amino acid sequence of the protein found in mother's milk. Founded in 2019 by food scientist Laura Katz, Helaina sells effera as a B2B ingredient to consumer wellness and supplement brands, targeting women's health, gut health, active nutrition and healthy aging. The company has raised roughly $84 million in equity funding, including a $45 million Series B in 2024.
Manus
Manus (Manus Bio) is an MIT-born industrial biotechnology company that engineers microbial cell factories and precision fermentation to produce natural ingredients - sweeteners, flavors, fragrances and pharmaceutical building blocks - that are normally extracted from plants or made from petrochemicals. Branded as 'The BioAlternatives Company,' Manus runs an R&D hub in Boston and a commercial-scale biomanufacturing plant in Augusta, Georgia, where it makes products such as monk fruit sweetener and stevia Reb M for partners including Givaudan and Tate & Lyle.
Circe
Circe (Circe Bioscience) is a Boston-based climate biotech company that engineers microbes to eat carbon dioxide and build valuable molecules - fats, oils, sugars, plastics and fuels - using only CO2, water and electricity. Spun out of Harvard's Wyss Institute in 2021, its gas-fermentation platform consumes roughly 3 kilograms of CO2 for every kilogram of oil it produces, making the process carbon-negative. The company has made the world's first chocolate using fermentation-derived cocoa butter and, in September 2024, raised a $5M seed round to open a pilot plant in Waltham, Massachusetts.
Solarbiotech
Solarbiotech is a U.S.-based synthetic biology and biomanufacturing company that helps companies move precision-fermentation products from lab bench to commercial scale. Built around a Norton, Virginia plant with fermentation capacity from 6L to 10,000L and a modular 'BioNodes' architecture, it offers end-to-end strain-to-shelf services - upstream fermentation, downstream processing, and commercial production - for food ingredients, nutraceuticals, cosmetics, enzymes, and industrial bioproducts. After a 2024 Chapter 11 restructuring, its assets were acquired by Pictor Biotech (led by ex-Novozymes executive Peter Rosholm) and unified in January 2025 with GPC Bio and Eleszto Genetika into a vertically integrated, 100+ person SynBio platform.
Triplebar
Triplebar is an Emeryville, California biotech company that pairs a high-throughput microfluidic screening platform with AI genomic models to run evolution at hyper-speed. By packing tens of millions of picoliter microreactors onto a palm-sized chip and testing thousands per second, it generates matched genotype-phenotype datasets that let partners optimize cell lines and microbial strains far faster and cheaper than conventional lab work. The platform powers products across food (precision fermentation, cultivated meat) and biopharma (biologics, cell-engaging cancer therapies).
TurtleTree
TurtleTree is a biotech and food-tech company that makes lactoferrin - one of the rarest and most valuable proteins in cow's milk - without the cow. Using precision fermentation, its flagship ingredient LF+ recreates the bioactive milk protein at scale for use in immunity, gut health, sports nutrition and infant nutrition products. In 2025 TurtleTree became the first company in the world to win an FDA 'No Questions' GRAS letter for precision-fermented lactoferrin, clearing it to commercialize in the U.S.
Perfect Day
Perfect Day is a Berkeley-based food-tech company that brews real dairy whey protein with microbes instead of cows. Using precision fermentation in steel tanks, it produces ProFerm - a beta-lactoglobulin identical to the protein in milk - and sells it as a B2B ingredient to food brands building animal-free ice cream, cream cheese, protein powders and beverages.
The EVERY Company
The EVERY Company is a San Francisco Bay Area biotech that uses precision fermentation to brew real egg proteins (ovalbumin, pepsin, and more) without chickens. Its ingredients - OvoPro, EVERY Egg White, and EVERY Protein - power baked goods, beverages, and protein bars sold by food brands ranging from startups to multinationals.