philadelphia-biotech
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Brian McVeigh Built a Career in the Space Between Science and the Deal
After 25 years at GSK and more than 100 transactions, the Philadelphia biotech executive made a founder's bet: the next leap in genetic medicine may depend less on the cargo than on the way it travels.
Thomas Han Built a Biotech Career at the Hand-Off
Thomas Han spent decades learning how medicines move from a promising idea to a durable business. At Peroxitech, he is applying that education to the hardest hand-off in biotech: turning university science into a company that can keep moving.
Peroxitech Put $25 Million Behind a Nine-Amino-Acid Bet on Saving Injured Lungs
The Philadelphia spinout is trying to stop acute lung injury before oxidative damage snowballs. Its unusually small peptide has survived mice, pigs and a $25 million financing - but the decisive human test still lies ahead.
Tahamtan Ahmadi
Tahamtan Ahmadi built his career in the hard middle of biotechnology - where a scientific idea must survive evidence, regulation, and scale. At Genmab, his remit now stretches from discovery to medicine, and his public philosophy keeps returning to curiosity, collaboration, and patient impact.
Dispatch Bio
Dispatch Bio is a Philadelphia-based cancer biotech that emerged from stealth in July 2025 with $216 million to pursue a 'universal' immunotherapy for solid tumors. Its first-in-class Flare platform uses an engineered virus to install a synthetic, tumor-specific antigen on cancer cells while remodeling the tumor's immune-suppressive environment, effectively giving CAR T cells a target where none existed. Founded in 2022 out of the Parker Institute for Cancer Immunotherapy and ARCH Venture Partners, the company is led by CEO Sabah Oney and counts CAR T pioneer Carl June among its scientific co-founders.
GEMMA Biotherapeutics
GEMMA Biotherapeutics (GEMMABio) is a Philadelphia-based gene therapy company spun out of the University of Pennsylvania and founded by AAV pioneer James M. Wilson. Launched in October 2024 with $34 million in seed funding, GEMMABio builds the research, manufacturing, and product-development infrastructure to move adeno-associated virus (AAV) gene therapies from the bench to the bedside faster and more affordably - with a focus on rare and ultra-orphan inherited diseases and a stated commitment to global patient access.
Ramon Salsas Escat
Ramon Salsas Escat is the Chief Business Officer of GEMMA Biotherapeutics (GemmaBio), the Philadelphia gene-therapy company spun out of Jim Wilson's lab to widen global access to AAV therapies for rare inherited diseases. A chemist by training who earned a PhD in computational and systems biology at MIT and an MBA at IESE, Salsas has led or co-led more than 20 transactions across AAV gene therapies, CNS disorders, oncology and manufacturing platforms, with cumulative deal value north of $4 billion in upfront payments and milestones. He helped build the business engine at Penn's Gene Therapy Program, served as SVP of Business Development at G2 Bio, and now runs business development, alliance management, legal and IP at GemmaBio, where he played a pivotal role in the company's founding and its $34 million seed round.
Fore Biotherapeutics
Fore Biotherapeutics is a Philadelphia-based, registration-stage precision oncology company developing targeted therapies for patients with hard-to-treat cancers. Its lead candidate, plixorafenib, is a next-generation BRAF inhibitor (a 'dimer breaker') aimed at BRAF-altered solid tumors, including BRAF V600E-mutated high-grade glioma, for which it received FDA Breakthrough Therapy Designation in 2026. Spun out of the Israeli functional-genomics company NovellusDx, Fore has raised more than $200M to push plixorafenib toward an accelerated FDA approval pathway.
Andrei Georgescu
Andrei Georgescu is the co-founder and CEO of Vivodyne, a biotech company that grows human tissues in the lab and runs drugs through them with robots and AI before any human ever swallows a pill. A University of Pennsylvania bioengineering PhD who once sent lab-grown tissue to space with NASA, he started Vivodyne in 2020 because roughly 19 of every 20 drugs that work in animals fail in people. His pitch is blunt: test human medicine on human tissue, not on mice. In May 2025 Vivodyne raised a $40 million Series A led by Khosla Ventures to scale a 23,000-square-foot fully robotic lab in South San Francisco.
Seneca Therapeutics, Inc.
Seneca Therapeutics is a clinical-stage biopharmaceutical company developing targeted oncolytic immunotherapeutics built on SVV-001, a non-pathogenic Seneca Valley Virus that selectively replicates in solid-tumor cells expressing the TEM8/ANTXR1 receptor. Founded by oncolytic-virus pioneer Dr. Paul Hallenbeck, the company pairs SVV-001 with immune modulators and checkpoint inhibitors to spark systemic anti-tumor immunity, and is advancing a Phase I/II trial in high-grade neuroendocrine neoplasms while building a pipeline of armed and neo-antigen viral constructs.
Michael Vidne
Michael Vidne is a Columbia-trained applied mathematician turned biotech founder who has spent the last decade moving cancer medicine from the lab bench to the clinic. He led the diagnostics company NovellusDx as CEO, steered its pivot into the precision-oncology drug developer Fore Biotherapeutics, and now builds at the intersection of AI, data, and healthcare as founder and CEO of the stealth-mode Baobab Therapeutics. His through-line: using rigorous models of complex systems - first neurons firing in the retina, later signaling pathways inside a tumor cell - to make treatment decisions that actually fit the patient in front of you.