kras
(4)
Nan Ji
Nan Ji is co-founder, president and CEO of PAQ Therapeutics, a Burlington, Massachusetts clinical-stage biotech pioneering autophagosome-tethering compounds (ATTECs) to degrade KRAS and other 'undruggable' disease drivers. A Harvard-trained organic chemist with 30+ patent applications, he spent seven years at Novartis, helped build Kymera Therapeutics from seed stage as VP of Chemistry, and launched PAQ in 2020 to hijack the body's natural cellular clean-up machinery for cancer and neurodegenerative disease.
Robert Ross
Robert Ross is a medical oncologist turned biotech executive and the founding CEO of Clasp Therapeutics, a Baltimore-based clinical-stage immuno-oncology company building bispecific T cell engagers that target mutated cancer driver peptides presented by HLA with what the company calls absolute specificity. Launched in March 2024 with a $150 million Series A from Third Rock Ventures, Novo Holdings and Catalio Capital, Clasp is commercializing science from Johns Hopkins legends Bert Vogelstein and Drew Pardoll. Ross previously ran Surface Oncology through its acquisition by Coherus, led oncology at bluebird bio, and trained as a physician at Columbia, Harvard, Stanford and UCSF.
Stig Hansen
Stig K. Hansen is a Danish-American biochemist and serial biotech founder who co-founded Kimia Therapeutics in 2023, a Berkeley-based precision chemistry company applying machine learning and automated synthesis to drug discovery. He previously co-founded and led Carmot Therapeutics for 15 years, inventing Chemotype Evolution technology that contributed to LUMAKRAS - the world's first FDA-approved KRAS G12C inhibitor for non-small cell lung cancer. Carmot was acquired by Roche for up to $3.1 billion in January 2024. At Kimia, Hansen is pioneering the ATLAS platform (AcTive Learning with Automated Synthesis and Screening), which integrates high-throughput chemistry, genome editing, and AI to map druggable chemical space at unprecedented scale. The company raised a $55 million Series A in December 2023 led by The Column Group and Dimension.
Chris Varma
Chris Varma, Ph.D., is Co-Founder, Chairman, and CEO of Frontier Medicines, a clinical-stage biotech attacking cancer's 'undruggable' proteins using chemoproteomics, covalent chemistry, and machine learning. A serial biotech founder with 20+ years in life sciences, he previously co-founded Blueprint Medicines (acquired by Sanofi for $9B+ in 2025) and Warp Drive Bio (acquired by Revolution Medicines in 2018), and held investor roles at Third Rock Ventures, Flagship Pioneering, and MPM Capital. His career spans the FDA, Novartis, and three successful company builds - with Frontier Medicines now advancing FMC-376, a first-in-class dual KRAS G12C inhibitor, through Phase 1/2 clinical trials.