Most venture capitalists sell a version of the same story: find software, watch it scale, ride the margins. Innovation Endeavors sells the opposite. The Palo Alto firm, co-founded in 2010 by former Google CEO Eric Schmidt, spends its time in the parts of the economy that resist software - the refineries, the cell cultures, the machine shops, the launchpads - and bets that they are about to change faster than anyone expects.
The firm calls the change the "Super Evolution." The name sounds grand, but the idea underneath it is specific. Three long technology curves, the partners argue, are crossing at the same moment: data has become cheap and everywhere, computation has become nearly free, and engineering itself - through robotics, 3D printing, and gene editing - has become programmable. When all three cross, a startup can re-architect a century-old industry in months rather than decades. Innovation Endeavors exists to fund the founders doing exactly that.
01What the firm actually does
Innovation Endeavors is an early-stage venture capital firm. In plain terms, it raises money from limited partners - institutions, endowments, family offices - and invests it as seed and Series A equity in young companies, aiming to return the capital many times over when those companies are acquired or go public. It earns a management fee on the money it holds and a share of the gains it produces.
That structure is ordinary. The selection is not. Where a generalist fund might spread dozens of small checks across consumer apps and business software, Innovation Endeavors concentrates on hard, science-heavy companies that most investors find too slow, too capital-hungry, or too technical to underwrite. Fund V, at $630 million, is meant to back only 30 to 35 companies. That is a deliberately narrow aperture - conviction over volume.

02The three forces behind the thesis
Strip away the branding and the Super Evolution is a claim about tools. Each of these forces was, until recently, a bottleneck. Together, they are becoming a launchpad.
Data
Cheap sensors made high-resolution data about the physical world ubiquitous - from satellites to live-cell microscopes.
Computation
Cloud infrastructure and machine learning turned modeling, simulation, and prediction into something close to a commodity.
Engineering
Robotics, 3D printing, and CRISPR made building - in metal, in atoms, in cells - programmable and iterable.
Startups can now re-architect deeply physical industries - agriculture, space, drug discovery - in days rather than years.- The Super Evolution thesis, in the firm's words
03Where it invests
When Innovation Endeavors closed Fund V, it organized its focus into three buckets. The categories are worth reading closely, because they explain why the same firm can hold a lending platform, a metal-forming robotics company, and an antibody discovery lab without contradiction.
The world made of atoms
Energy, climate, infrastructure, and materials - the capital-heavy sectors where software has barely arrived.
Biology as engineering
Therapeutics and diagnostics built on gene editing, computation, and high-resolution biological data.
Selling shovels
The core tools and platforms that scientists and engineers themselves rely on to do the work.
Early and active
Seed and Series A checks, often as lead, with hands-on help recruiting technical talent and raising follow-on capital.
04Who it backs
The firm's customer, in a sense, is a person: the technical founder. Often that founder has just left a PhD program, a national lab, or a research group, and is trying to turn a result on a lab bench into a company. Partner Scott Brady has put the case for backing fresh talent bluntly - by his reckoning, if you finished your doctorate more than five years ago, you are probably no longer current in the fastest-moving technical fields.
That belief shapes how the firm sources deals. It also produced one of its more unusual habits: Curiosity Camp, an invite-only, title-free gathering in the Santa Cruz mountains where physicists, rocket scientists, computational biologists, founders, and policymakers pick sessions by which idea sounds most interesting rather than who is speaking. It is a recruiting tool disguised as a retreat, and a fair summary of the firm's taste.
If you did your PhD more than five years ago, you're really not current in a lot of these technologies.- Scott Brady, Founding Partner
05The track record
Innovation Endeavors is not new, and the portfolio shows it. The firm was an early investor in SoFi and Uber, the rocket company Astra, the delivery platform Slice, and the synthetic biology company Zymergen. Across fifteen years it has backed more than 150 companies, over two dozen of which have reached unicorn valuations.
Fund III and IV figures are approximate, drawn from third-party reporting. Fund V is confirmed.
06How it differs from the alternatives
Innovation Endeavors competes with a small set of firms that also chase hard technology - Lux Capital, DCVC, The Engine, Founders Fund, Khosla Ventures, and 8VC among them. What separates it is less a single tactic than a posture: a willingness to underwrite the long, uncertain gap that deep-tech founders call the "valley of death," the stretch between a scientific breakthrough and a business that can stand on its own. Generalist funds tend to avoid that gap. Innovation Endeavors built its model around crossing it.
The firm's own logo is a quiet tell. It is a ring of radiating lines meant to read as a gear, a motor, or a propeller - something mathematical and stable that is also, always, in motion. That is roughly the kind of company it wants to fund.
07The road so far
The firm is founded
Eric Schmidt co-founds Innovation Endeavors in Palo Alto with Dror Berman, Scott Brady, and Rick Scanlon.
The thesis takes shape
The Super Evolution view is formalized and Curiosity Camp launches as an annual frontier-science gathering.
Deepening the deep-tech focus
Successive funds concentrate the portfolio around the physical economy, life sciences, and enabling infrastructure.
Fund V closes at $630M
The firm raises its largest fund, planning to back 30 to 35 science-driven companies.
Active deployment
Fund V moves into new manufacturing, biotech, and data-infrastructure companies as the thesis plays out.
08Where it fits in the market
Zoom out and Innovation Endeavors occupies a particular seat: an early-stage, science-first fund large enough to lead rounds and patient enough to wait out physical timelines, but focused enough to stay expert in the fields it plays in. It is not trying to be the biggest venture firm, or the fastest. It is trying to be the one technical founders call first when their company is too weird, too hard, and too early for everyone else - and it has fifteen years of results arguing the seat is worth holding.
09Questions people ask
What does Innovation Endeavors invest in?
Early-stage (seed and Series A) deep-tech and science-driven startups across the physical economy - energy, climate, manufacturing, materials - plus life sciences and the enabling infrastructure scientists and engineers rely on.
Who founded it?
It was founded in 2010 by former Google CEO Eric Schmidt with Dror Berman, Scott Brady, and Rick Scanlon. It is based in Palo Alto, California.
What is the "Super Evolution" thesis?
The idea that cheap data, abundant computation, and new engineering tools are converging so completely that startups can re-architect deeply physical industries in months rather than decades.
How big is the latest fund?
Innovation Endeavors closed Fund V at $630 million in January 2024 - its largest fund - and planned to invest it across roughly 30 to 35 companies.
What notable companies has it backed?
Early investments include SoFi, Uber, Astra, Slice, and Zymergen, alongside a broad portfolio of deep-tech and life-sciences companies.