tumor-microenvironment
(4)
Steven Everett
Steven Everett is a biotechnology executive and cancer scientist who founded MaveriX Oncology in Palo Alto, California, where he serves as President and CEO. With a background rooted in more than two decades of cancer research at the University of Oxford, University of Dundee and UCSF, he has built his career around a single idea: making cancer drugs that switch on only inside tumors. At MaveriX he is developing conditionally activated small-molecule therapeutics that exploit hydroxylase biology in the tumor immune microenvironment, aiming to hit cancer hard while sparing healthy tissue.
J. Gene Wang
J. Gene Wang is a physician-scientist and the founder and CEO of Immetas Therapeutics, a biotech he co-founded in 2018 with Harvard's David Sinclair to attack the chronic, low-grade inflammation that drives aging and age-related cancers. Trained with an M.D. from Peking University and a Ph.D. in immunobiology from Yale, Wang spent roughly two decades inside Merck, Abbott, GSK, and Novartis, where he helped move blockbuster drugs like Humira, Gardasil, Zolinza, and Varubi from lab bench to patients. At Immetas he is engineering bispecific antibodies designed to retune inflammation inside the tumor microenvironment and break resistance to checkpoint immunotherapy, backed by an $11M Series A from Morningside Ventures.
Sean McCarthy
Sean McCarthy is the chairman, president and CEO of CytomX Therapeutics, a clinical-stage biopharma in South San Francisco building 'Probody' conditionally activated antibodies that switch on inside the tumor and stay quiet everywhere else. An Oxford-trained cancer biologist turned operator, he has run CytomX since 2011, taking it from a venture-backed startup to a Nasdaq-listed company with partnerships across Bristol Myers Squibb, AbbVie, Amgen, Astellas, Moderna and Regeneron.
Scott Clarke
Scott Clarke is the CEO of CatalYm GmbH, a Munich-based biotech company developing visugromab, a monoclonal antibody targeting GDF-15 to reverse cancer immunotherapy resistance. With over 20 years in biopharmaceuticals - spanning Roche's global oncology partnering, BioMarin, Tizona Therapeutics, and Ambagon Therapeutics - Clarke joined CatalYm in January 2025 to lead the company's $319M-funded push through Phase 2b clinical trials, building on visugromab's striking Phase 1/2a results published in Nature showing durable responses lasting 28-32+ months in multiple solid tumor types.