Supira Medical is a clinical-stage cardiovascular device company in Los Gatos, California, building a next-generation percutaneous ventricular assist device (pVAD). Incubated inside Amr Salahieh's Shifamed innovation hub and led by CEO Nitin Salunke, the Supira System is a low-profile (10F), high-flow heart pump designed to give the heart temporary circulatory support during high-risk coronary interventions and cardiogenic shock, with the goal of moving more blood through a smaller sheath than the incumbent devices. The company raised a $120M oversubscribed Series E in March 2025 and won FDA approval to begin its SUPPORT II pivotal trial in 2026.
Adona Medical is a clinical-stage medical device company in Los Gatos, California developing the Delphi System, a chronically adjustable interatrial shunt with integrated bi-atrial pressure monitoring designed to personalize heart failure therapy over time. A Shifamed portfolio company founded in 2019 by Brian Fahey, Amr Salahieh, and Lewis Schwartz, Adona uses shape memory nitinol and an external induction catheter to resize the shunt after implantation without further invasive procedures.
Siesta Medical, Inc. is a privately held medical device company in Los Gatos, California that builds minimally invasive implants and instruments to treat obstructive sleep apnea (OSA). Its flagship AIRLIFT procedure - performed with the FDA-cleared Encore System and the Revolution Suture Passer - lets ear, nose and throat surgeons pull the hyoid bone and tongue base forward to keep the airway open during sleep. The knotless, fully adjustable approach takes roughly 30 minutes, works regardless of a patient's anatomy, BMI or apnea severity, and has been used in more than 2,000 patients.
Tenon Medical is a Los Gatos, California medical device company that built the Catamaran SI Joint Fusion System, a patented, less-invasive way to fuse the sacroiliac joint with a single titanium implant placed along an inferior-posterior trajectory. Founded in 2012 and public on the Nasdaq since 2022 (TNON), Tenon targets the often-overlooked SI joint, a frequent and hard-to-diagnose source of chronic lower-back pain. In 2025 it expanded into a multi-product sacro-pelvic platform by acquiring the SiVantage SImmetry technology portfolio.
El Camino Health is a not-for-profit healthcare system that has served Silicon Valley and the South Bay for more than 60 years. Born from a 1950s community vote and a tax that residents levied on themselves, it runs two acute care hospitals in Mountain View and Los Gatos plus roughly two dozen care locations across Santa Clara County. With 471 beds, about 4,480 employees and 1,585 physicians, it blends a community-rooted mission with the technology-forward instincts of the valley it sits in.