CardioRenal Systems is a Milford, Massachusetts medical device company developing RenalPro (marketed as RenalGuard outside the US), an automated fluid-management system that prevents acute kidney injury in high-risk hospital settings. By monitoring urine output in real time and matching IV hydration in milliliter increments, the system keeps patients balanced during cardiac surgery, catheter procedures, and ICU care. RenalPro holds FDA Breakthrough Device Designation and a CE Mark, and in a 220-patient randomized UK trial cut AKI by 52% versus standard care.
CoapTech is a Baltimore-based medical technology company that built the world's first ultrasound-guided gastrostomy system. Its FDA-cleared PUMA-G System lets bedside clinicians place feeding tubes using only ultrasound imaging and a patented magnet-aligned catheter, replacing procedures that traditionally required an operating room, endoscopy, or interventional radiology. The approach aims to make feeding-tube placement faster, safer, and cheaper, and has been used in more than 1,000 patients across ICUs, step-down units, and long-term acute care hospitals.
Scott Roth is a cardiologist who spent two decades reading echocardiograms before deciding the ICU needed a faster way to see the heart. As founder and CEO of ImaCor, he built hemodynamic ultrasound (hTEE) around the disposable, pencil-thin ClariTEE probe that stays in a patient for up to 72 hours, giving clinicians a live look at cardiac filling and function instead of waiting on lab results. In 2022 ImaCor and Clarius released the Zura Handheld, billed as the world's first handheld TEE system, putting that view in a 22-ounce device.