general-catalyst
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The Venture Firm That Bought a Hospital
General Catalyst spent 25 years turning startups into giants. Then it did something no venture firm had done before - it bought a hospital.
Yuzu Health
Yuzu Health is a New York-based healthtech company that rebuilds the administrative backbone of health insurance into a single, white-labeled system of record. Operating as a vertically integrated third-party administrator (TPA), Yuzu runs the behind-the-scenes engine for claims processing, payments, and member administration, letting insurers, brokers, and self-funded employers launch highly configurable plan designs - direct provider contracts, cash-pay options, and dynamic copays - without the heavy services burden of legacy administrators. Founded in 2022, the company works with customers across all 50 states and has processed more than $1 billion in claims payment volume.
Chariot Defense
Chariot Defense is a South San Francisco defense-technology company building hybrid-electric power systems for the battlefield. Its Amphora platform delivers quiet, high-density, software-controlled power to distributed military hardware - drones, sensors, radios, electronic-warfare and directed-energy systems - so that energy never becomes the limiting factor in a fight. Founded in 2024 by former Anduril and Archer engineer Adam Warmoth, the company raised a $34M Series A led by Andreessen Horowitz in February 2026, bringing total funding to roughly $41-42M, and has fielded its systems with the U.S. Army and the Defense Innovation Unit.
AfterHour
AfterHour is a San Francisco social trading app that lets retail investors link their real brokerage accounts and post their actual positions - in full dollar amounts - to a public feed under a pseudonym. The twist is verification: you can talk your book, but the app proves you're holding what you claim. Founded by Kevin Xu, the WallStreetBets folk hero known as 'Sir Jack A Lot' who turned roughly $35,000 into millions during the meme-stock era, AfterHour combines verified portfolios, live stock chat rooms, and real-time trade signals into one community. It raised a $4.5M seed round led by Founders Fund and General Catalyst in June 2024.
Aurelius Systems
Aurelius Systems is a San Francisco defense-technology startup building Archimedes, an autonomous, high-powered laser turret that detects, tracks and neutralizes drones in seconds for roughly the cost of electricity. Founded in 2024 by photonics veterans Michael LaFramboise and John Marmaduke, the company fuses commercial off-the-shelf hardware, advanced optics and AI-guided targeting into a compact, low-cost counter-UAS platform aimed at protecting soldiers and critical infrastructure from cheap, swarming aerial threats.
Haize Labs
Haize Labs is a New York-based AI safety and reliability startup that automates the red-teaming, stress-testing, and evaluation of large language models. Founded in 2024 by a trio of Harvard-trained researchers, the company builds algorithms that hunt for the inputs that make AI models misbehave - jailbreaks, failure modes, and edge cases - so they can be fixed before real users find them. Its 'haizing suite' and multi-turn attack engine Cascade are used by frontier model labs including OpenAI and Anthropic, alongside enterprises like Deloitte and MongoDB.
Percepta
Percepta is a New York-based AI transformation company, wholly owned and incubated by venture firm General Catalyst, that embeds teams of researchers, engineers, and product managers directly inside large enterprises to move them past AI pilots and into AI-native operations. Founded in 2025 by CEO Hirsh Jain (a former Palantir SVP) and General Catalyst's Hemant Taneja, the company pairs applied engineering with a frontier research lab to rebuild core workflows in healthcare, financial services, manufacturing, and government - working closely with founding partners Anthropic and AWS.
Fabric
Fabric is a New York-based care enablement company building an AI-powered operating layer that sits on top of hospital and health system technology to automate clinical and administrative work. Its platform spans a Digital Front Door, virtual and in-person care suites, patient engagement, and a 50-state clinical network, all stitched together by a hybrid AI that combines conversational models with clinical logic. Founded by Aniq Rahman, the former Moat president, Fabric grew fast through product plus four acquisitions in 18 months and now reaches more than 75 health systems and roughly 100 million covered lives.
Thatch
Thatch is a San Francisco health benefits platform that lets employers give workers a tax-free monthly healthcare budget instead of a one-size-fits-all group plan. Employees shop a marketplace for their own medical, dental and vision coverage, then spend any leftover budget on care through a Thatch debit card. Built around ICHRA - a 2020-era IRS rule - the company aims to unbundle health insurance from a single employer plan and hand the choice back to individuals. Since launching in 2023 it has served more than 1,000 businesses and raised about $84.5 million across seed, Series A and Series B rounds.
Triumph
Triumph (Triumph Labs) is a San Francisco company that turns ordinary mobile games into real-money skill tournaments. Its plug-and-play SDK lets developers add cash competitions with a single line of code, while Triumph handles the hard parts behind the scenes: payments, KYC identity checks, state-by-state legal compliance, geolocation, matchmaking, anti-cheat, and payouts. Founded in 2021 by Stanford dropouts Jake Brooks and Jared Geller, the company raised $14.1M (a $10.2M Series A led by General Catalyst plus a $3.9M seed) and also runs its own consumer apps - Triumph Arcade for skill games and Rips for card collectibles.
WonderHowTo Network
WonderHowTo Network is a Santa Monica-based digital media company that helps curious people learn how to do almost anything. Founded in 2006 by former TV executive Stephen Chao and technologist Michael Goedecke, it began as a search engine and directory for instructional how-to videos and grew into a network of specialized brands - Gadget Hacks, Null Byte, Next Reality, Food Hacks Daily and more - covering smartphones, white-hat hacking, augmented reality and everyday DIY. At its peak the network reached roughly 12 million monthly unique visitors.
Pallet
Pallet is a San Francisco AI startup building an 'AI workforce' for the physical economy. Its flagship product, CoPallet, automates back-office freight workflows - order entry, quoting, document parsing, portal updates - that have historically required armies of human operators, working inside systems like McLeod, Revenova, Turvo and even legacy AS400 stacks. In 2026 it added Atlas, a data-intelligence layer that surfaces hidden revenue opportunities across a supply chain network.