
After turning a regional distribution operation into a $35 million sales engine, Daniel Pontecorvo spent the next decade building devices, teams and a tightly focused company that sold for up to $75 million.

A planned surgical career became a decade-long lesson in risk, reinvention and patient-centered product design. The result is Alio - and a founder’s playbook built around fast decisions, aligned incentives and the discipline to change course.
Raj Amin is the co-founder and CEO of Arcade Therapeutics, a New York science-first game studio building prescription digital therapeutics that embed clinically proven anxiety-reduction techniques inside mobile games. A University of Pennsylvania-trained engineer and Wharton MBA, he has spent more than two decades building venture-backed companies at the seam of healthcare, media and technology - including HealthiNation, the first on-demand consumer health video network, and Mana Health, a health-data interoperability platform later acquired by Comcast. He is a self-described #GirlDad, a drummer and aspiring guitarist, and a Broadway investor who has backed Tony Award-winning productions.
Robert K. Weigle is a medical device and diagnostics executive with more than 25 years of experience taking healthcare products from pre-clinical research to commercial launch. He is CEO of NOW Diagnostics, an independent board member of Tenon Medical, and a former entrepreneur-in-residence at DigitalDx Ventures. He led Benvenue Medical as CEO for over a decade, raising more than $200 million and launching spine devices in two markets, and later ran saliva-based diagnostics companies focused on cancer detection. His career spans Fortune 500 names like Johnson & Johnson and Baxter as well as a string of venture-backed startups.

Mike Yang is the co-founder and CEO of LuxCreo, the company behind the world's first FDA Class II 510(k)-cleared direct-print clear aligner. A Harvard PhD and Wharton MBA, Yang spent a decade at Bloom Energy raising over $1B in green technology before pivoting to reinvent dentistry with light-based additive manufacturing. Under his leadership LuxCreo secured backing from Kleiner Perkins, achieved FDA clearance in 2022, launched in Europe in 2025, and is pushing same-day, in-clinic aligner production into mainstream dentistry.
Bob Schafer, PhD, is the CEO of Lumos Labs, the company behind Lumosity, the world's largest brain training platform with over 100 million users. A Stanford-trained neuroscientist with postdoctoral work at MIT, Schafer founded Prophecy Sciences (YC W13) before joining Lumos Labs via acquihire in 2015. He rose from Head of Research to Chief Science Officer to President of Lumosity DTx before being named CEO in May 2023. Under his leadership, Lumos Labs achieved FDA 510(k) clearance in December 2025 for LumosityRx (marketed as Prismira), the first prescription digital therapeutic for attention improvement in adults with ADHD — validated by a 500-participant randomized controlled trial.