Dispatch
Co-Founder & CEO, Arcade Therapeutics Three venture-backed companies and counting Wharton + Penn Engineering StarStarter Rx on the FDA clearance track #GirlDad. Drummer. Aspiring guitarist. Broadway investor with two Tony winners Co-Founder & CEO, Arcade Therapeutics Three venture-backed companies and counting Wharton + Penn Engineering StarStarter Rx on the FDA clearance track #GirlDad. Drummer. Aspiring guitarist. Broadway investor with two Tony winners
Raj Amin, co-founder and CEO of Arcade Therapeutics
Profile / Builder at the seam of play and medicine

Raj Amin

He builds video games a doctor can prescribe. The game is the bait. The medicine is hidden inside.

Arcade Therapeutics New York Digital Therapeutics Serial Founder
What he is doing now

A science-first game studio that treats anxiety like an engagement problem.

Two-thirds of Americans play games. Raj Amin looked at that number and saw a waiting room. Arcade Therapeutics, the company he co-founded in 2019, builds mobile games that smuggle a clinically proven psychological technique inside the fun. You think you are playing. You are also, quietly, retraining the way your attention reacts to threat.

The flagship is StarStarter Rx, described as the first game-based treatment for anxiety. It has completed pilot trials and is pursuing clearance from the FDA. The mechanism is attention bias modification, the practice of nudging the unconscious mindsets and cognitive biases that feed anxiety. The wrapper is something people actually want to open. That gap, the distance between treatment that works and treatment that people will use, is the whole point of Raj Amin's career.

His framing is blunt. The hardest part of mental health care is not the science. It is the front door. Therapy works, but getting a human being to walk in and stay is the obstacle that defeats most of it. So he built a door shaped like a game.

What if you could embed a psychological technique into the game that is proven to reduce anxiety symptoms? That is what we have done at Arcade.

- Raj Amin
100M+
HealthiNation monthly viewers
3
Venture-backed companies co-founded
2/3
Of Americans play games
20+
Years in health, media & tech
The pattern
A career, decoded

He keeps finding the format people will use.

Look across two decades and the same instinct repeats. Pick something important but unloved, then deliver it through a channel people already enjoy. Health information became television. Health data became infrastructure. Now therapy becomes a game.

HealthiNation

The first on-demand consumer health video network, co-founded in 2005. It reached more than 100 million monthly viewers and 40 million cable homes - turning dry medical advice into watchable television.

Mana Health

A health-data platform built for record access and interoperability, later acquired by Comcast Connected Health. The unglamorous plumbing of healthcare, made usable.

Arcade Therapeutics

Software as medicine. Evidence-based therapeutic games that a clinician can prescribe and, increasingly, that insurance can reimburse. The format problem, solved with a controller.

The long road

From DVRs to digital medicine.

Before he was prescribing play, he was shipping the gadgets and platforms that taught a generation how to consume media on demand.

Early
Led interactive TV partnerships at Scientific-Atlanta, later acquired by Cisco.
Early
Senior Product Manager at ReplayTV, one of the original DVR pioneers.
Early
VP of Advertising & Content Markets at N2 Broadband, acquired by Ericsson.
2005
Co-founded HealthiNation, the first on-demand consumer health video network.
2010s
Co-founded Mana Health, later acquired by Comcast Connected Health.
2019
Co-founded Arcade Therapeutics with Tracy Dennis-Tiwary.
Now
Founding Partner at Teem Ventures; Partner at OysterLabs; advancing StarStarter Rx toward FDA clearance.
In his own words

The creative side is the actual job.

🎤

The reset

He plays guitar, then shifts back to a business problem. Context-switching, he calls it - a deliberate way to shake an idea loose.

💡

The superpower

"I have a creative side in how I think about new businesses. I've applied that to the problems I see in the world that I feel need solving."

🎬

The conviction

"We need to democratize the way that early-stage companies get built." A builder who wants more builders in the room.

The make-up of a builder

Engineer who reads the balance sheet.

The biography hides a useful clue. Raj Amin holds degrees from both the Wharton School and Penn's Moore School of Engineering and Applied Science. One side of the diploma can read a circuit. The other can read a cap table. That double fluency explains a lot about a person who keeps starting companies where the technology is hard and the business model is harder.

At Arcade he has assembled the unlikely trio that game-based medicine demands: cognitive neuroscience, clinical psychology, and the craft of building a game you do not want to put down. His co-founder, Tracy Dennis-Tiwary, brought the academic spine. He brought the instinct for engagement he had been sharpening since the days of on-demand cable. The result is a category that barely existed a decade ago, prescription digital therapeutics, now buoyed by new CMS billing codes that let digital mental health treatment qualify for reimbursement.

He is candid that the model is unfinished. The science has to clear regulators. The reimbursement has to clear insurers. The game has to clear the highest bar of all, which is a bored teenager deciding to open it again tomorrow. But the thesis is clean: meet people where they already are, and treatment stops being a chore.

There is a civic thread, too. He sits on the board of Musicians on Call, the nonprofit that carries live music to hospital bedsides. He has put money behind early-stage founders through Teem Ventures and OysterLabs, and he talks about crowdfunding less as a fad than as a way to let people back the companies they believe in. The through-line is access. Access to care, access to capital, access to a little joy in a hospital room.

And then there is Broadway. The same man who pitches FDA pathways has invested in Tony Award-winning theater, including revivals of A Raisin in the Sun and the punk-rock musical American Idiot. It is a tell. Whether the medium is a stage, a screen, or a smartphone game, he is drawn to the moment when a story grabs a person and will not let go. That grip, harnessed for health, is the bet of his life right now.

SchoolingWharton (business) and Penn's Moore School (engineering), University of Pennsylvania.
Day jobCo-Founder & CEO, Arcade Therapeutics, New York.
Also buildingFounding Partner, Teem Ventures. Partner, OysterLabs.
Gives backBoard Member, Musicians on Call.
Off the clockSelf-described #GirlDad, drummer, and aspiring guitarist.
Plot twistInvestor in Tony-winning Broadway shows, including American Idiot.

One of the biggest challenges to engaging people is really the format of that engagement. It is a big obstacle to get people into therapy.

- Raj Amin, on why the wrapper matters as much as the medicine
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Sources: digitalraj.com, arcadetherapeutics.com, Superpowers for Good, LinkedIn, ShootOnline, Crunchbase.