brain-health
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Russ Lebovitz
Russ Lebovitz is the co-founder and CEO of Amprion, a precision brain diagnostics company that built the first commercial seed amplification assay for detecting misfolded alpha-synuclein - the protein at the root of Parkinson's disease and other synucleinopathies. An MD/PhD trained at Washington University in St. Louis and a former research physician at Baylor and Fox Chase Cancer Center, Lebovitz spent years chasing prions after the mad cow scare, then pivoted the same detection science toward common neurodegenerative diseases. His SYNTap test won an FDA Breakthrough Device Designation and is now used in clinical trials and patient care to spot brain disease years before symptoms appear.
David Matthews
David Matthews, PhD, is Chief Business Officer at Beacon Biosignals, the computational neurodiagnostics company turning EEG brain data into AI-powered biomarkers for neurological and psychiatric disease. A computational neuroscientist by training, he spent two decades moving between the lab, the boardroom, and the market - from NIH- and NSF-funded research at the Salk Institute to a partnership at Boston Consulting Group to commercial leadership at digital-health platform BrightInsight. He now drives partnerships and commercial growth at a company betting that the brain can be measured at home, at scale.
Jacob Donoghue
Jacob Donoghue is a physician-scientist and the co-founder and CEO of Beacon Biosignals, a Boston company applying machine learning to EEG brain data to build neurobiomarkers for psychiatric, neurological, and sleep disorders. Trained with an MD from Harvard Medical School and a PhD in neuroscience from MIT, he started Beacon in 2019 on the bet that decades of overlooked brainwave recordings could be turned into a precision-medicine engine for drug development and diagnosis. Under his leadership the company has raised over $116M, secured FDA clearance for a wearable EEG headband, acquired home sleep-testing firm CleveMed, and partnered with more than half of the world's top ten biopharma companies.