antibody-engineering

(4)
Legend
Jason Gardner
Executive · Founder · Scientist

Jason Gardner

Jason Gardner is the CEO of Ampersand Biomedicines and a CEO-Partner at Flagship Pioneering, where he leads a Boston-area biotech programming biologic medicines that act only at the site of disease. A Cambridge- and Oxford-trained scientist turned operator, he previously co-founded and ran Magenta Therapeutics through its IPO and spent years building GSK's Regenerative Medicine Unit. He is betting that the next generation of drugs will not just be potent but precise - going exactly where they are needed and nowhere else.

biotech · ceoRead →
Legend
Alexey Lugovskoy
Founder · Executive · Scientist

Alexey Lugovskoy

Alexey 'Alex' Lugovskoy is the co-founder and CEO of Diagonal Therapeutics, a Watertown/Cambridge, Massachusetts biotech building 'clustering' antibodies that switch cellular signaling back on rather than block it. A Harvard-trained biophysicist who left physics after deciding green leaves were more interesting than tau neutrinos, he spent two decades in antibody R&D at Biogen, Merrimack, Morphic, and Dragonfly before launching Diagonal in 2022. He has co-invented an FDA-approved cancer drug, authored more than 100 patents and papers, and edits the antibody journal mAbs. In January 2026 Diagonal closed an oversubscribed $125M Series B co-led by Sanofi Ventures and Janus Henderson to push its lead program, DIAG723, into human trials for hereditary hemorrhagic telangiectasia.

diagonal-therapeutics · clustering-antibodiesRead →
Legend
Jennifer Cygan
Executive · Operator · Advisor

Jennifer Cygan

Jennifer Cygan is a seasoned biotech executive and Chief Business Officer at EpiBiologics, where she helps advance a pipeline of novel bispecific antibodies designed to selectively degrade extracellular protein targets in oncology and immunology. With a Ph.D. from Harvard and over two decades of business leadership in biotechnology, she has been a pivotal force at Genentech, Calico Life Sciences (managing a $2.5B AbbVie alliance), and has co-founded and served as CBO for multiple emerging biotech companies including Broadwing Bio, Eikon Therapeutics, GenEdit, and Plexium. Her career sits at the intersection of science and strategy - translating cutting-edge biology into deals, partnerships, and companies that matter.

biotechnology · biopharmaceuticalsRead →
Legend
Roy Maute
Founder · Executive · Scientist

Roy Maute

Roy Maute is co-founder and CEO of Pheast Therapeutics, a clinical-stage biotech in Redwood City, CA, developing macrophage-targeted cancer immunotherapies. Trained at UC Berkeley, Columbia (PhD, Genetics), and Stanford (postdoc under Irving Weissman), Maute has built a career at the intersection of innate immunology and drug development. Before Pheast, he co-founded Ab Initio Biotherapeutics (acquired by Ligand in 2019) and led translational research at Forty Seven Inc. ahead of its $4.9B acquisition by Gilead in 2020. At Pheast, he is advancing PHST001, a novel anti-CD24 antibody that teaches macrophages to eat cancer cells, currently in Phase 1 clinical trials with FDA Fast Track Designation for ovarian cancer.

biotech · cancer-immunotherapyRead →