als

(7)
Legend
J. Robert Coleman
Founder · Executive · Scientist

J. Robert Coleman

J. Robert Coleman, PhD, MBA, is Chairman and CEO of HERVolution Therapeutics, a Copenhagen-based biotech developing immunotherapies that target human endogenous retroviruses (HERVs) - the ancient viral DNA lodged in the dark genome that reawakens in cancer, aging, and neurodegeneration. A trained virologist, he co-founded Codagenix, where he built a synthetic-biology vaccine platform into a clinical-stage pipeline and raised nearly half a billion dollars before pivoting to HERVs in late 2023.

biotech · dark-genomeRead →
Legend
Stan Abel
Executive · Founder · Operator

Stan Abel

Stan Abel is President and CEO of ProJenX, a clinical-stage biotech spun out of Columbia University research and Project ALS, racing to get its lead drug prosetin - an oral MAP4K inhibitor - into ALS patients after two decades of laboratory work and a $15 million Series A.

biotech · alsRead →
Legend
Alice Zhang
Founder · Executive · Scientist

Alice Zhang

Alice Zhang is the CEO and co-founder of Verge Genomics (now Verge Labs), a San Francisco biotech she started in 2015 after walking away from an MD/PhD program at UCLA. She built a company that pairs machine learning with one of the largest collections of human brain tissue to find drug targets for diseases like ALS, Parkinson's and Alzheimer's. A Princeton molecular biology graduate, Soros Fellow and Forbes 30 Under 30 honoree, Zhang turned her inexperience into what she calls a 'superpower,' raising more than $130 million and partnering with Eli Lilly and AstraZeneca before pivoting the company toward selling its data and insights to pharma in 2025.

alice-zhang · verge-genomicsRead →
Legend
Christopher Reyes
Founder · Scientist · Executive

Christopher Reyes

Christopher Reyes is a biophysicist turned serial biotech entrepreneur and the CEO, co-founder, and director of Bloom Science, a San Diego company developing living medicines that harness the gut-brain axis. Bloom's lead program, BL-001, is a first-in-class oral live biotherapeutic designed to replicate the anti-seizure effects of the ketogenic diet, built on technology licensed from UCLA. With a PhD in biophysics from UCSF and a track record that includes a fast-acquired cancer startup, Reyes is betting that genetically optimized gut bacteria can treat pharmacoresistant neurological diseases.

christopher-reyes · bloom-scienceRead →
Legend
Asa Abeliovich
Founder · Scientist · Executive

Asa Abeliovich

Asa Abeliovich is a physician-scientist turned serial biotech founder who spent two decades at the lab bench at Columbia before deciding the only way to get his ideas into patients was to start companies. He co-founded Alector, founded and sold Prevail Therapeutics to Eli Lilly for about $1 billion, and now runs Leal Therapeutics, a Worcester startup chasing a contrarian idea: that fixing the brain's broken metabolism can treat everything from schizophrenia to ALS to Alzheimer's. Leal spent over two years in stealth before surfacing with a clinical-stage pipeline and roughly $114 million raised.

asa-abeliovich · leal-therapeuticsRead →
Legend
Eric Green
Founder · Executive · Scientist

Eric Green

Eric Green is the Founder and CEO of Trace Neuroscience, a South San Francisco biotech company racing to develop the first effective ASO therapy for ALS. A Harvard-and-Stanford-trained physician-scientist with a background in cardiology, Green co-founded iLab Solutions (acquired by Agilent), Respira Design (Stanford $50K Challenge winner), and Maze Therapeutics before launching Trace with a $101 million Series A in November 2024. Trace's lead program targets UNC13A - a protein lost in ALS patients - using an antisense oligonucleotide designed to restore healthy nerve-muscle communication. With clinical trials targeting early 2026, Green is betting human genetics can do for ALS what it did for heart failure.

als · neuroscienceRead →
Legend
Vishwanath Lingappa
Founder · Executive · Scientist

Vishwanath Lingappa

Vishwanath Lingappa is the CEO and CTO of Prosetta Biosciences, a San Francisco-based biotechnology company he founded in 2003 after 22 years as a faculty member at UCSF. An MD-PhD with a doctorate from The Rockefeller University under Nobel laureate Gunter Blobel, Lingappa developed a proprietary Cell-Free Protein Synthesis System (CFPSS) drug discovery platform that targets transient multi-protein complexes - a class of drug targets largely ignored by traditional pharma. His company is pursuing small-molecule therapeutics across neurodegenerative diseases (Alzheimer's, ALS, Parkinson's), oncology, and infectious diseases (COVID-19, HIV, influenza), and won an ARPA-H Dash competition for a pan-cancer drug candidate. With over 157 publications and 12,800+ citations, Lingappa bridges rigorous academia with commercial biotech ambition.

biotechnology · drug-discoveryRead →