PlenOptika is a Cambridge, Massachusetts medical device company that makes QuickSee, a handheld autorefractor that measures a person's eyeglass prescription in about ten seconds using wavefront aberrometry and machine-learning algorithms. Spun out of the Madrid-MIT M+Vision fellowship in 2014, the company set out to close the gap on uncorrected refractive error, a problem affecting more than a billion people worldwide. Its portable, clinic-quality device has been used by vision professionals and NGOs on over 5 million patients in more than 45 countries - and even flew aboard SpaceX's Polaris Dawn mission as the first handheld autorefraction device used in space.
Liane Clamen is a Harvard-trained ophthalmologist and the founder and CEO of Adaptilens, a Newton, Massachusetts biotech building a biomimetic accommodating intraocular lens that imitates the young human lens so cataract patients can see near, intermediate, and distance without glasses. She sketched the idea more than two decades ago, fought the patent office to a 2019 grant, and in April 2024 closed a $17.5 million Series A to push the device toward its first human trial.