Triplebar

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Maria Cho and the art of thinking small

Maria Cho went from selling knives to leading a company that miniaturizes biological experiments. Her career keeps returning to a practical question: how does a good idea become something people can actually use?

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Legend

Executive · Scientist · Operator

Shawn Manchester

Shawn Manchester is the CEO of Triplebar, an Emeryville-and-Oakland based biotech building generative AI 'genome language models' paired with ultra-high-throughput phenotypic screening to slash the cost of biologic therapeutics and food proteins. A chemical engineer by training (BS Brown, PhD MIT), he was the lead scientist in the first AI-versus-human strain engineering contest at Zymergen before joining Triplebar in 2021, where he rose from VP of Product to COO to CEO in March 2025.

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