It made light bulbs, then TVs, then the CT scanner in your local hospital. The story of how a Dutch electronics giant reinvented itself as a pure health-tech company - and nearly lost the bet.
David Weber, PhD, is the President and CEO of Mosanna Therapeutics, a Redwood City biotech developing MOS118, a bedtime nasal spray for obstructive sleep apnea that aims to restore the body's natural airway reflex during sleep. A biotech operator with more than 30 years in drug development, capital formation, and corporate strategy, he previously led Otonomy through its IPO and multiple clinical programs, and served as CEO of MacuSight and Oculex Pharmaceuticals. He joined Mosanna in June 2025 as the company launched with an $80 million Series A.
Mosanna Therapeutics is a clinical-stage biotech developing MOS118, a bedtime nasal spray for obstructive sleep apnea (OSA). Rather than mechanically forcing the airway open like CPAP, MOS118 is a small molecule pan-K+ channel inhibitor that reactivates the body's own negative pressure reflex - stimulating pressure-sensing nerves in the nasopharynx to increase upper airway muscle tone and reduce apnea episodes. Founded in 2022 and headquartered in Redwood City, California with an office in Basel, Switzerland, the company launched publicly in June 2025 with an $80 million Series A to advance MOS118 through Phase 2.
Wesper is a New York-based sleep-health company that has built a wireless, wearable patch and cloud platform for clinical-grade, at-home sleep apnea testing. Founded in 2017 (originally as Tatch) by Dr. Amir Reuveny and Adi Mordechai, Wesper combines flexible printed electronics, machine learning, and a provider portal to replace the wires and single-night snapshots of traditional sleep labs with comfortable, repeatable, longitudinal testing. The FDA-cleared Wesper Lab lets patients test at home while giving physicians high-resolution data that correlates closely with in-lab polysomnography.
XII Medical is a Union City, California medical device company building a minimally invasive neuromodulation therapy for obstructive sleep apnea (OSA). Founded in 2017 and led by CEO Garrett Schwab, the company is developing an implantable platform designed to be smaller, more flexible and easier to implant than existing nerve-stimulation systems - an alternative for the estimated 425 million people worldwide with moderate-to-severe OSA who struggle with CPAP masks. Backed by Cleveland Clinic, Ajax Health, Omega Funds and Intuitive Ventures, XII Medical closed a $45M Series B in August 2024 to fund product and clinical development.
Neru Health is a Boston-based vertical AI company automating patient support and resupply for durable medical equipment (DME) providers and sleep clinics. Its platform centers on Nora, an AI 'active sleep coach' that texts, calls, and emails patients to troubleshoot CPAP devices, coach therapy adherence, and coordinate supply reorders, backed by a digital-phenotyping engine that personalizes each interaction. Spun out of Harvard's Blavatnik Fellowship in 2023 after co-founder Morgan Moncada struggled to get care for his own sleep apnea, Neru says it now serves 30,000+ patients and cuts provider labor costs by up to 60%.
Vena Vitals is an Irvine, California medical-device startup building a soft, skin-worn sticker sensor that continuously measures blood pressure without a cuff or an arterial line. Spun out of UC Irvine biomedical engineering research, its VeriTrack system uses a patented wrinkled-metal capacitive pressure sensor to capture beat-to-beat data with accuracy validated against arterial lines in operating rooms across the country. Founded in 2019 by Ray Liu, Michelle Khine, and Josh Kim and backed by Y Combinator, the company is pursuing FDA clearance to bring continuous, noninvasive blood pressure monitoring first into hospitals and later into homes.
Siesta Medical, Inc. is a privately held medical device company in Los Gatos, California that builds minimally invasive implants and instruments to treat obstructive sleep apnea (OSA). Its flagship AIRLIFT procedure - performed with the FDA-cleared Encore System and the Revolution Suture Passer - lets ear, nose and throat surgeons pull the hyoid bone and tongue base forward to keep the airway open during sleep. The knotless, fully adjustable approach takes roughly 30 minutes, works regardless of a patient's anatomy, BMI or apnea severity, and has been used in more than 2,000 patients.
Sleep Reset is a San Francisco digital sleep clinic that brings the methods of an in-person sleep center to a phone. Built around Cognitive Behavioral Therapy for Insomnia (CBT-I), it pairs each user with a human sleep coach and a personalized, multi-week program instead of pills. Founded by serial entrepreneur Yunha Kim after her own years-long battle with insomnia and sleep apnea, the program was developed with researchers from Stanford, Yale and other institutions, and is used by thousands of people seeking a no-pill path to better sleep.
CPAP.com is the largest internet retailer of CPAP equipment for sleep apnea treatment, founded in 1999 by Johnny Goodman and his father in Stafford, Texas. The family-owned e-commerce company carries over 1,000 products including CPAP machines, BiPAP machines, masks, and accessories from all major brands, helping more than 2.3 million people find effective sleep apnea therapy. With 25+ years of experience, a community of 40,000+ members on CPAPtalk.com, and institutional backing from Cathay Capital and The Silverfern Group, CPAP.com has become the go-to destination for both new and experienced sleep apnea patients navigating their treatment journey.
Joe Megibow is a serial CEO and digital commerce veteran who has led some of the most recognizable consumer brands in sleep — from Purple Innovation and Casper Sleep to cpap.com — building a career defined by turning legacy industries on their heads through e-commerce, omnichannel strategy, and relentless operational focus. With stops at Expedia, American Eagle Outfitters, and a handful of successful exits along the way, Megibow brings three decades of digital disruption experience to every seat at the table.