protein-dynamics
(2)
Shengfang Jin
Shengfang Jin is a co-founder and the President and CEO of Ensem Therapeutics, a Waltham, Massachusetts biotech developing small-molecule cancer drugs by targeting protein pockets that only exist while the protein is in motion. Under Jin, Ensem built its Kinetic Ensemble platform, took its first CDK2 inhibitor into the clinic, and its ETX-636 breast cancer program earned FDA Fast Track designation. She trained at Tufts and Harvard, spent years at Agios helping deliver first-in-class cancer metabolism drugs, and then ran discovery biology at Editas before starting Ensem.
Huafeng Xu
Huafeng Xu is the founder and CEO of Fathom Therapeutics (formerly AtomMap), a New York drug-design company that simulates protein motion at atomic resolution to design small molecules that work inside living cells. A computational chemist with 25+ years and 10,000+ citations, Xu spent 12 years at D. E. Shaw Research building the free-energy and molecular-dynamics methods now standard across pharma, then served as CTO of Silicon Therapeutics and Roivant Discovery before launching his own company. In April 2026 Fathom closed an oversubscribed $47M Series A led by Sutter Hill Ventures to scale its Microcosmos engine.