protein-design
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Ajay Kshatriya
Ajay Kshatriya is the CEO and co-founder of Aizen Therapeutics, a San Diego biotech that spun out of Caltech to build 'Mirror Peptides' - drugs made entirely of D-amino acids, the mirror image of the proteins nature uses. The company launched from stealth in November 2024 with $13M and a generative-AI platform called DaX. Before Aizen, Ajay founded and ran Biota, an environmental genomics company acquired by Novozymes in 2021 after creating roughly $400M in economic value and saving 1.2 billion gallons of water for industrial clients. A UC Berkeley and Stanford-trained chemical engineer who began his career at Genentech and learned company-building as a seed investor at XSeed Capital, he now also invests in Caltech science startups as a partner at Wilson Hill Ventures.
Deniz Kavi
Deniz Kavi is the co-founder and CEO of Tamarind Bio, a San Francisco company that turns hundreds of complex computational-biology models - AlphaFold, RFdiffusion, OpenFold and more - into a point-and-click web tool and API so scientists can design drug candidates without writing code or wrangling cloud infrastructure. A Stanford computer-science graduate who did computational-biology research and engineered software at Stanford School of Medicine, he started the company in 2023 with co-founder Sherry Liu, went through Y Combinator's W24 batch, and in February 2026 raised a $13.6M Series A led by Dimension Capital. Tamarind now serves 10,000+ scientists, including 8 of the top 20 global pharma companies, and was tapped to run the inference infrastructure behind Eli Lilly's TuneLab 2.0.
Marc Lajoie
Marc Lajoie is a protein designer turned biotech CEO. He co-founded Outpace Bio in 2021 in Seattle, where he is chief executive, building engineered cell therapies that aim to bring the kind of cures seen in blood cancers to the solid tumors that make up the vast majority of cancer cases. Trained in George Church's genome-engineering lab at Harvard and David Baker's Institute for Protein Design at the University of Washington, Lajoie helped pioneer the design of proteins with moving parts - molecules that compute, switch, and make decisions inside living cells. Outpace raised a $144M oversubscribed Series B in 2024 to push its AI-powered, protein-designed therapies toward the clinic.
Ali Madani
Ali Madani is the founder and CEO of Profluent, the AI-first protein design company based in Emeryville, California. A machine learning researcher by training, he holds a PhD from UC Berkeley and pioneered the use of large language models to generate functional proteins from scratch - first at Salesforce AI Research as the architect of ProGen, then at Profluent where his team created OpenCRISPR-1, the world's first AI-designed and open-source gene editor, published in Nature in 2025. With $150M in total funding from Bezos Expeditions, Altimeter Capital, Spark Capital, and Insight Partners, Madani is on a mission to make biology programmable - designing proteins that don't exist in nature to solve the biggest challenges in human health, agriculture, and biomanufacturing.