penn-medicine
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J. Eduardo Rame
J. Eduardo Rame is a Philadelphia cardiologist who treats the sickest hearts in medicine - patients in the final stage of heart failure who depend on pumps, transplants and the chance their own muscle can be coaxed back to life. As the Louis R. Dinon MD Professor and enterprise chief of Advanced Cardiac and Pulmonary Vascular Disease at Jefferson Health, he runs an integrated division built around recovery rather than replacement. Yale-trained in biophysics, Oxford-trained in health economics and Harvard-trained in medicine, he spent a decade founding Penn's mechanical circulatory support program before bringing that work to Jefferson. His research on left ventricular assist devices, including the landmark MOMENTUM 3 trial, has been cited more than 12,000 times.
Justin Bekelman
Justin Bekelman is the co-founder and CEO of Daymark Health, a Philadelphia-based value-based oncology company building a tech-enabled medical group that wraps clinical, mental health, and social support around people facing cancer. A radiation oncologist with roughly 200 published research articles, he spent two decades at the University of Pennsylvania, where he founded the Penn Center for Cancer Care Innovation at the Abramson Cancer Center before leaving to build a company that contracts directly with health plans to take on total cost of care. Daymark launched publicly in 2025 with $11.5M in seed funding and closed a $20M Series A in September 2025.