The company that runs the plumbing behind American medical bills is betting AI can drain billions in administrative waste - and half the country's patients are already in its pipes.
Collectly is a San Francisco-based healthcare fintech that automates the patient side of revenue cycle management. Its AI platform plugs into more than 20 EHR and practice-management systems to run digital billing, eligibility checks, cost estimates, payments and follow-up, so medical groups collect more, faster, with fewer staff hours. Founded in 2017 and a Y Combinator graduate, Collectly says it serves 3,000+ healthcare facilities and has processed over $1 billion in patient payments. In 2025 it launched Billie, a 24/7 AI agent that answers patient billing questions and takes action across voice, chat, text and email.
Mural Health is a Berwyn, Pennsylvania-based clinical research technology company whose Mural Link platform is billed as the industry's first participant management system. It combines patient payments, travel and rideshare booking, two-way messaging, and real-time experience feedback into one participant-first tool aimed at helping people enroll in and stay in clinical trials while easing the administrative burden on research sites and sponsors. Founded in 2022 by Sam Whitaker - the inventor of the original ClinCard payment technology at Greenphire - the company positions itself against legacy prepaid-card systems, notably by eliminating the inactivity fees that quietly drain participant balances.