The New York firm has nearly $900 million, fewer than 10 new bets a year and a taste for founders still sketching the future. Its wager is that operating experience and patient conviction can beat venture capital by trend cycle.
HC9 Ventures built its pitch around a simple diagnosis: healthcare startups rarely fail for lack of software alone. They fail in the maze between a promising product and the institutions that must buy, trust, and deploy it.
Spun out of one of the world's most secretive trading firms, Jump Capital has spent a decade quietly funding the infrastructure that markets, money, and software run on - and it prefers the unglamorous parts.
For 17 years, Simplify Healthcare quietly ran the paperwork behind 70-plus health plans. In late 2025 its founder folded that experience into a four-company group betting that operational scar tissue, not just models, is what makes enterprise AI actually work.
Rule 1 Ventures spent years turning freight, finance and security headaches into B2B software. Now the Atlanta firm is applying the same operator-first logic to aerospace and defense - where access, speed and execution matter as much as capital.
Unlock Venture Partners built its seed strategy around a simple map: two major technology cities, too little early capital, and founders who need more than a wire transfer.