The Bay Area startup tried to replace phone trees and staffing middlemen with a map, a calendar and instant clinician matching. Its short public trail offers a sharper lesson than another tidy startup victory lap.
Halodoc is a Jakarta-based digital health platform that lets Indonesians consult licensed doctors, order medicine for home delivery, book lab tests and appointments, and buy insurance from a single mobile app. Founded in 2016 by Jonathan Sudharta and Doddy Lukito, it connects more than 20 million monthly active users with over 20,000 doctors, 4,000+ pharmacies and 1,400+ hospitals, and has raised roughly US$258 million led by Indonesian conglomerate Astra, Temasek and Novo Holdings.
Transhuman Inc. is a mental health and emotionAI research and development company founded in 2014 by Amanda Johnstone and Dr. Roy Sugarman. Best known for its free peer-support check-in app Be A Looper, which operated in 87 countries, the company builds proprietary EmotionAI technologies at the intersection of artificial intelligence, the Internet of Bodies (IoB), and human emotion. Its focus is on suicide prevention, emotional communication, and human-to-computer relationships.
Azumio is a Redwood City, California digital health company that builds AI-powered mobile apps and developer APIs for tracking heart rate, food, sleep, fitness and diabetes. Founded in 2011 out of the runaway success of its Instant Heart Rate app, Azumio's consumer titles - including Argus, Calorie Mama, Glucose Buddy, Fitness Buddy and Sleep Time - have collectively surpassed 100 million downloads. The company also licenses its computer-vision technology to businesses through the Calorie Mama / Food Lens food-recognition API and its Instant Diabetes Test and health-data platform APIs.
Constant Therapy is a Boston-area digital health company that turns speech, language, and cognitive rehabilitation into an AI-personalized app. Spun out of Boston University's Aphasia Research Laboratory in 2012, its platform delivers more than 100,000 evidence-based exercises across 80-plus task categories to people recovering from stroke, traumatic brain injury, aphasia, dementia, and other neurological conditions - and to the clinicians who treat them. A patented NeuroPerformance Engine adapts each session to the individual, extending therapy beyond the clinic and into daily home practice.
Swing Therapeutics is a San Francisco digital therapeutics company building software-based treatments for chronic illness. Its flagship product, Stanza, is the first FDA-cleared prescription digital therapy for fibromyalgia, delivering acceptance and commitment therapy (ACT) through a smartphone in roughly 15 minutes a day. The company also operates Swing Care, a telehealth clinic that prescribes and supports the therapy across multiple states.
Triple W USA makes DFree, the first wearable ultrasound sensor that predicts when you need to use the bathroom. The matchbox-sized device sits on the lower abdomen, tracks bladder fullness in real time, and sends an alert to a phone or tablet before it is too late. Founded by Atsushi Nakanishi in 2015 and headquartered in San Diego, the company sells to individuals, caregivers, and senior care facilities under the banner of dignity and independent living - 'diaper-free.'
Medisafe is a digital health company that turns the everyday struggle of taking pills on time into a behavior-driven engagement platform. Born from a near-fatal insulin overdose in the founders' own family, it began as a free virtual pillbox app and grew into an enterprise platform - anchored by Medisafe Maestro and its Just-in-Time Interventions (JITI) engine - that pharmaceutical companies use to keep patients on therapy. With more than 13 million users worldwide and 4+ billion doses tracked, Medisafe sits at the intersection of consumer mobile health and the multibillion-dollar problem of medication non-adherence.
HealthTap is a Sunnyvale-based digital health company that connects patients with board-certified physicians 24/7 through video, phone, and text consultations. Founded in 2010, it operates a platform of 105,000 doctors across 141 specialties serving 23 million monthly members. The company pairs AI-powered symptom checking with live clinical consultations, offering affordable virtual primary and urgent care via subscription or per-visit pricing. Recent partnerships with Samsung Health, Eli Lilly's LillyDirect, and Commure signal a shift toward deep integration with major consumer and clinical platforms.
Hello Heart is a Menlo Park-based digital health company exclusively focused on cardiovascular health. Founded in 2013, it offers an AI-powered mobile app paired with a connected blood pressure monitor and smart pill box that helps members understand, track, and improve their heart health. Deployed through employers, health plans, and Medicare Advantage programs, Hello Heart has served users at 150+ Fortune 500 companies and government organizations. Independent peer-reviewed studies - including a JAMA study of 28,000+ participants - show that 84% of high-risk users reduced blood pressure over three years, with average medical cost savings exceeding $1,700 per enrolled member per year. The company has raised $148.5 million in total funding, most recently a $70 million Series D in May 2022.