Marilyn Matz is the CEO and co-founder of Paradigm4, the Waltham, Massachusetts company behind SciDB, an array-native computational database built for the tangled, multi-dimensional data of genomics, clinical research, and imaging. She launched it in 2010 with database legend and Turing Award laureate Mike Stonebraker to move his MIT research into the hands of working scientists. Decades earlier she left MIT to co-found Cognex, now a global machine-vision powerhouse, where she ran worldwide engineering and later a business unit. A two-time technical founder who codes the deep infrastructure and still sells to the customer, Matz has spent a career making impossibly large scientific data explorable, reproducible, and fast.
Qian Li is the co-founder and CEO of DBOS, Inc., a Cambridge- and San Francisco-based company turning a once-academic idea into infrastructure: store a program's execution state inside Postgres so crashed apps and AI agents resume exactly where they left off. A Stanford computer science PhD, she co-founded DBOS in 2023 out of a joint Stanford-MIT research project led by Postgres creator Mike Stonebraker and Spark co-creator Matei Zaharia. She was named to the Silicon Valley Business Journal's 40 Under 40 in 2025, won a USENIX ATC Best Paper award for INFaaS, and is a regular voice on systems podcasts and conference stages on durable, observable, scalable software.