longevity-biotech
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The Cell That Forgot How to Be Young
NewLimit wants to make an old cell useful again without making it forget what kind of cell it is. Its first test of that idea is headed from the liver lab toward human trials.
Zoe Biosciences Found a Longevity Clue in Amish DNA. Now It Has to Turn That Clue Into a Drug
A rare mutation pointed to longer, healthier lives. Zoe's bet is that two drug programs can borrow the biology without borrowing the mutation - and its newest mouse data put obesity, muscle preservation and a very expensive clinical test on the same page.
Adam Freund
Adam Freund is the founder and CEO of Arda Therapeutics, a San Carlos biotech built on a simple, contrarian bet: many chronic diseases are caused by specific cells gone wrong, so the cure is to find and delete those cells while leaving healthy tissue intact. A molecular biologist with a Berkeley PhD and a Stanford postdoc, he spent seven years at Google-backed Calico Life Sciences, where he helped grow the company from roughly 15 to 200-plus people and started its most advanced anti-aging therapeutic program. In late 2021 he left to start Arda as a solo founder with a deck and a thesis, and by October 2024 had raised a $43M Series A led by a16z Bio + Health. His tools are single-cell sequencing to map disease cell-by-cell and antibodies to do the deleting.